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    Gxylt2 glucoside xylosyltransferase 2 [ Mus musculus (house mouse) ]

    Gene ID: 232313, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Gxylt2provided by MGI
    Official Full Name
    glucoside xylosyltransferase 2provided by MGI
    Primary source
    MGI:MGI:2682940
    See related
    Ensembl:ENSMUSG00000030074 AllianceGenome:MGI:2682940
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm152; Glt8d4
    Summary
    Predicted to enable UDP-xylosyltransferase activity. Predicted to be involved in O-glycan processing. Predicted to be located in membrane. Is expressed in aorta; embryo mesenchyme; incisor; and musculoskeletal system. Orthologous to human GXYLT2 (glucoside xylosyltransferase 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in ovary adult (RPKM 8.5), limb E14.5 (RPKM 8.0) and 13 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Gxylt2 in Genome Data Viewer
    Location:
    6 D3; 6 46.9 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (100681638..100787738)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (100704672..100810888)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700049E22 gene Neighboring gene STARR-seq mESC enhancer starr_16870 Neighboring gene SHQ1 homolog (S. cerevisiae) Neighboring gene ubiquitin-conjugating enzyme E2 variant 2 pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr6:100621045-100621346 Neighboring gene high mobility group box 3 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E1325 Neighboring gene STARR-positive B cell enhancer ABC_E2197 Neighboring gene STARR-seq mESC enhancer starr_16873 Neighboring gene protein phosphatase 4, regulatory subunit 2 Neighboring gene STARR-seq mESC enhancer starr_16877 Neighboring gene STARR-seq mESC enhancer starr_16880 Neighboring gene transmembrane protein 258 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

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    Homology

    Clone Names

    • MGC59592

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables UDP-xylosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-xylosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables UDP-xylosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in O-glycan processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in O-glycan processing ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in O-glycan processing ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glucoside xylosyltransferase 2
    Names
    glycosyltransferase 8 domain containing 4
    glycosyltransferase 8 domain-containing protein 4
    NP_941014.1
    XP_006506070.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198612.2 → NP_941014.1  glucoside xylosyltransferase 2

      See identical proteins and their annotated locations for NP_941014.1

      Status: PROVISIONAL

      Source sequence(s)
      AC121925, AC155648
      Consensus CDS
      CCDS20390.1
      UniProtKB/Swiss-Prot
      Q810K9
      Related
      ENSMUSP00000032157.8, ENSMUST00000032157.9
      Conserved Domains (2) summary
      cd06430
      Location:111 → 414
      GT8_like_2; GT8_like_2 represents a subfamily of GT8 with unknown function
      COG1442
      Location:127 → 396
      RfaJ; Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      100681638..100787738
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006506007.5 → XP_006506070.1  glucoside xylosyltransferase 2 isoform X1

      Conserved Domains (2) summary
      PHA03247
      Location:30 → 110
      PHA03247; large tegument protein UL36; Provisional
      cl11394
      Location:111 → 370
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q810K9.1 GenPept UniProtKB/Swiss-Prot:Q810K9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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