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    CTSD cathepsin D [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703534, updated on 5-Mar-2024

    Summary

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    Gene symbol
    CTSD
    Gene description
    cathepsin D
    See related
    Ensembl:ENSMMUG00000003874
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See CTSD in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (1831927..1867517, complement)
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (15285166..15296969)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (1590284..1631888, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (15507837..15540978)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene keratin-associated protein 5-6 Neighboring gene interferon induced transmembrane protein 10 Neighboring gene 60S ribosomal protein L36a Neighboring gene actin, cytoplasmic 1-like

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene meiosis regulator and mRNA stability factor 1 Neighboring gene microRNA mir-484 Neighboring gene nudE neurodevelopment protein 1 Neighboring gene myosin heavy chain 11 Neighboring gene U6 spliceosomal RNA Neighboring gene centrosomal protein 20 Neighboring gene 60S ribosomal protein L15 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables aspartic-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cathepsin D
    Names
    cathepsin D preproprotein
    NP_001247483.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260554.1 → NP_001247483.1  cathepsin D precursor

      See identical proteins and their annotated locations for NP_001247483.1

      Status: PROVISIONAL

      Source sequence(s)
      JV043195
      UniProtKB/TrEMBL
      A0A5F8ABN7, A0A5F8AGH6
      Related
      ENSMMUP00000075290.1, ENSMMUT00000092989.1
      Conserved Domains (2) summary
      cd05490
      Location:73 → 408
      Cathepsin_D2; pepsin family of proteinases
      pfam07966
      Location:22 → 49
      A1_Propeptide; A1 Propeptide

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      1831927..1867517 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      15285166..15296969
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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