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    APOC1 apolipoprotein C1 [ Canis lupus familiaris (dog) ]

    Gene ID: 476437, updated on 17-Aug-2024

    Summary

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    Official Symbol
    APOC1provided by VGNC
    Official Full Name
    apolipoprotein C1provided by VGNC
    Primary source
    VGNC:VGNC:37999
    See related
    Ensembl:ENSCAFG00845006666
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    Apo-CI; ApoC-I; Apo-CIB; ApoC-IB
    Orthologs
    human mouse all
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    Genomic context

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    See APOC1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (111049949..111052329, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (110001120..110003506, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (111228866..111231250, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (110724595..110726986, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (110360068..110362462, complement)

    Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene apolipoprotein C2 Neighboring gene apolipoprotein C4 Neighboring gene apolipoprotein E Neighboring gene translocase of outer mitochondrial membrane 40

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and expression of dog apolipoprotein A-I, E, and C-I mRNAs: implications for the evolution and functional constraints of apolipoprotein structure. Luo CC, et al. J Lipid Res, 1989 Nov. PMID 2515239

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables fatty acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lipoprotein metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of cholesterol transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of lipoprotein lipase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of very-low-density lipoprotein particle clearance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in triglyceride metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in very-low-density lipoprotein particle clearance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of high-density lipoprotein particle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of very-low-density lipoprotein particle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    apolipoprotein C-I

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001197048.1 → NP_001183977.1  apolipoprotein C-I precursor

      See identical proteins and their annotated locations for NP_001183977.1

      Status: VALIDATED

      Source sequence(s)
      JAAUVH010000354
      UniProtKB/Swiss-Prot
      P56595
      UniProtKB/TrEMBL
      A0A8C0KHJ0
      Related
      ENSCAFP00845009224.1, ENSCAFT00845011823.1
      Conserved Domains (1) summary
      pfam04691
      Location:27 → 86
      ApoC-I; Apolipoprotein C-I (ApoC-1)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051805.1 Reference ROS_Cfam_1.0

      Range
      111049949..111052329 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049261.1 Alternate UMICH_Zoey_3.1

      Range
      110724595..110726986 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

      Range
      110360068..110362462 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

      Range
      111228866..111231250 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      110001120..110003506 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P56595.1 GenPept UniProtKB/Swiss-Prot:P56595

    Gene LinkOut

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