DHRS2 dehydrogenase/reductase 2 [Saimiri boliviensis (Bolivian squirrel monkey)] - Gene

Summary

Gene symbol: DHRS2
Gene description: dehydrogenase/reductase 2
See related: EnsemblRapid:ENSSBOG00000022947
Gene type: protein coding
RefSeq status: INFERRED
Organism: Saimiri boliviensis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Saimiriinae; Saimiri
Orthologs: human mouse all
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Genomic context

Location:: chromosome: Un

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
102	current	BCM_Sbol_2.0 (GCF_016699345.1)	Unplaced Scaffold	NW_024100921.1 (61925030..61938997, complement)

NW_024100921.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NW_024100921 Unplaced Scaffold Reference BCM_Sbol_2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

This locus identifies S. boliviensis DHRS2 gene, ortholog of human DHRS2 gene. They have identical exon-intron structure, splicing phases and the rare GC dinucleotide of the splice-donor intron sequence between the 7th and 8th exon; their coded proteins have identical catalytic amino-acid, Rossman fold consensus and the three amino-acid typical of vertebrate DHRS2 enzymes. DHRS2 gene is a duplicate form of the DHRS4 one.
Title: Molecular and functional evolution of human DHRS2 and DHRS4 duplicated genes.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables carbonyl reductase (NADPH) activity	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: dehydrogenase/reductase SDR family member 2, mitochondrial

Names: dehydrogenase/reductase SDR family member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001278540.1 → NP_001265469.1 dehydrogenase/reductase SDR family member 2, mitochondrial

See identical proteins and their annotated locations for NP_001265469.1

Status: INFERRED

Source sequence(s)

JAEKCL010000210

UniProtKB/TrEMBL

A0A2K6SXZ8

Conserved Domains (2) summary

PRK07231
Location:34 → 275

fabG; 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional

cl21454
Location:28 → 275

NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

RefSeqs of Annotated Genomes: Saimiri boliviensis Annotation Release 102 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCM_Sbol_2.0 Primary Assembly

Genomic

NW_024100921.1 Reference BCM_Sbol_2.0 Primary Assembly

Range

61925030..61938997 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_010334927.1 → XP_010333229.1 dehydrogenase/reductase SDR family member 2, mitochondrial isoform X1

See identical proteins and their annotated locations for XP_010333229.1

UniProtKB/TrEMBL

A0A2K6SXZ8

Related

ENSSBOP00000012276.1, ENSSBOT00000029066.2

Conserved Domains (2) summary

PRK07231
Location:34 → 275

fabG; 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional

cl21454
Location:28 → 275

NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins