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    CGR1 Cgr1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852854, updated on 29-Jun-2024

    Summary

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    Gene symbol
    CGR1
    Gene description
    Cgr1p
    Primary source
    FungiDB:YGL029W
    Locus tag
    YGL029W
    See related
    SGD:S000002997; AllianceGenome:SGD:S000002997; VEuPathDB:YGL029W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in rRNA processing. Located in nucleolus. Part of preribosome, large subunit precursor. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See CGR1 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (440063..440425)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene ribosomal 60S subunit protein L24A Neighboring gene ribosomal 60S subunit protein L30 Neighboring gene tRNA-Phe Neighboring gene putative glucan endo-1,3-beta-D-glucosidase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning of cgrA, the gene encoding the Aspergillus nidulans ortholog of Saccharomyces cerevisiae CGR1. Sun J, et al. Curr Microbiol, 2001 Jun. PMID 11381331
    2. Cgr1p, a novel nucleolar protein encoded by Saccharomyces cerevisiae orf YGL0292w. Sun J, et al. Curr Microbiol, 2001 Jan. PMID 11116400
    3. Identification of a role for Saccharomyces cerevisiae Cgr1p in pre-rRNA processing and 60S ribosome subunit synthesis. Moy TI, et al. Microbiology (Reading), 2002 Apr. PMID 11932453
    4. Differentiating mechanisms of toxicity using global gene expression analysis in Saccharomyces cerevisiae. Caba E, et al. Mutat Res, 2005 Aug 4. PMID 15878181
    5. Differential subcellular localization of ribosomal protein L7 paralogs in Saccharomyces cerevisiae. Kim TY, et al. Mol Cells, 2009 May 31. PMID 19466602

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in rRNA processing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosome biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of preribosome, large subunit precursor HDA PubMed 

    General protein information

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    Preferred Names
    Cgr1p
    NP_011486.1
    • Protein involved in nucleolar integrity and processing of pre-rRNA; has a role in processing rRNA for the 60S ribosome subunit; transcript is induced in response to cytotoxic stress but not genotoxic stress; relocalizes from nucleus to nucleolus upon DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      440063..440425
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180894.1 → NP_011486.1  TPA: Cgr1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011486.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VUA9, P53188
      UniProtKB/TrEMBL
      A0A6A5PUZ0, A6ZUW5, B3LIP2, C7GS96, C8Z8L3, G2WE65, N1P1Z1
      Conserved Domains (1) summary
      pfam03879
      Location:12 → 119
      Cgr1; Cgr1 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53188.1

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