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    cd99l2 CD99 molecule-like 2 [ Danio rerio (zebrafish) ]

    Gene ID: 323266, updated on 2-Nov-2024

    Summary

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    Official Symbol
    cd99l2provided by ZNC
    Official Full Name
    CD99 molecule-like 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-1986
    See related
    Ensembl:ENSDARG00000056722 AllianceGenome:ZFIN:ZDB-GENE-030131-1986
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb969; mic2l1; fb93g04; wu:fb93g04
    Summary
    Predicted to act upstream of or within cell adhesion. Predicted to be located in anchoring junction and plasma membrane. Is expressed in nervous system; neural plate; pharyngeal arch 3-7 skeleton; tail bud; and trigeminal placode. Orthologous to human CD99L2 (CD99 molecule like 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See cd99l2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (25878553..25895354, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (25607360..25624271, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene myotubularin 1 Neighboring gene myotubularin related protein 1a Neighboring gene uncharacterized LOC108190781 Neighboring gene high mobility group box 3a Neighboring gene arrestin, beta 2b Neighboring gene uncharacterized LOC137496167

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Cloning, genomic organization, alternative transcripts and expression analysis of CD99L2, a novel paralog of human CD99, and identification of evolutionary conserved motifs. Suh YH, et al. Gene, 2003 Mar 27. PMID 12706889
    2. In vivo protein trapping produces a functional expression codex of the vertebrate proteome. Clark KJ, et al. Nat Methods, 2011 Jun. PMID 21552255, Free PMC Article
    3. Single cell sequencing of radial glia progeny reveals the diversity of newborn neurons in the adult zebrafish brain. Lange C, et al. Development, 2020 Jan 9. PMID 31908317, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in anchoring junction IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    CD99 antigen-like protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001328523.1 → NP_001315452.1  CD99 antigen-like protein 2 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      BX005022, EH433396, EH459401, EH591607
      UniProtKB/TrEMBL
      A0A0H2UKE9, A0A8M1P513
      Related
      ENSDARP00000073701.4, ENSDART00000079245.5
      Conserved Domains (1) summary
      pfam12301
      Location:39 → 232
      CD99L2; CD99 antigen like protein 2

    2. NM_001328524.1 → NP_001315453.1  CD99 antigen-like protein 2 isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      BX005022, EH433396, EH459401, EH591607
      UniProtKB/Swiss-Prot
      Q6DBW9, Q8QFW9
      Related
      ENSDARP00000073691.6, ENSDART00000079235.7
      Conserved Domains (1) summary
      pfam12301
      Location:39 → 231
      CD99L2; CD99 antigen like protein 2

    3. NM_001328525.1 → NP_001315454.1  CD99 antigen-like protein 2 isoform 4 precursor

      Status: VALIDATED

      Source sequence(s)
      BX005022, EH433396, EH459401, EH591607
      UniProtKB/TrEMBL
      A0A2R8Q1M7, A0A8M1P3Y8
      Related
      ENSDARP00000147027.1, ENSDART00000187568.1

    4. NM_194369.2 → NP_919350.2  CD99 antigen-like protein 2 isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      BX005022, EH433396, EH459401, EH591607
      UniProtKB/Swiss-Prot
      Q6DBW9
      Related
      ENSDARP00000142717.1, ENSDART00000173505.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      25878553..25895354 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005172253.5 → XP_005172310.1  CD99 antigen-like protein 2 isoform X7

      UniProtKB/TrEMBL
      A0A8M2BJM1
      Conserved Domains (1) summary
      pfam12301
      Location:39 → 213
      CD99L2; CD99 antigen like protein 2

    2. XM_005172252.5 → XP_005172309.1  CD99 antigen-like protein 2 isoform X6

      UniProtKB/TrEMBL
      A0A8M2BJJ6
      Conserved Domains (1) summary
      pfam12301
      Location:39 → 230
      CD99L2; CD99 antigen like protein 2

    3. XM_009303031.4 → XP_009301306.1  CD99 antigen-like protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A8M3BAU8
      Conserved Domains (1) summary
      pfam12301
      Location:39 → 231
      CD99L2; CD99 antigen like protein 2

    4. XM_009303030.4 → XP_009301305.1  CD99 antigen-like protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8M3AU10
      Conserved Domains (1) summary
      pfam12301
      Location:86 → 267
      CD99L2; CD99 antigen like protein 2

    5. XM_017356813.3 → XP_017212302.1  CD99 antigen-like protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8M6Z7M7
      Related
      ENSDARP00000142684.1, ENSDART00000173786.2

    6. XM_009303029.4 → XP_009301304.1  CD99 antigen-like protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M3B105
      Conserved Domains (1) summary
      pfam12301
      Location:87 → 267
      CD99L2; CD99 antigen like protein 2

    7. XM_009303028.4 → XP_009301303.1  CD99 antigen-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5NSB9, A0A8M3B3X2
      Related
      ENSDARP00000142732.1, ENSDART00000173602.2
      Conserved Domains (1) summary
      pfam12301
      Location:87 → 268
      CD99L2; CD99 antigen like protein 2
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6DBW9.1 GenPept UniProtKB/Swiss-Prot:Q6DBW9

    Gene LinkOut

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