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    btbd6.L BTB (POZ) domain containing 6 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 398279, updated on 4-Nov-2024

    Summary

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    Official Symbol
    btbd6.L
    Official Full Name
    BTB (POZ) domain containing 6 L homeolog
    Primary source
    Xenbase:XB-GENE-6251792
    Locus tag
    XELAEV_18039766mg
    See related
    EnsemblRapid:ENSXLAG00005017379 AllianceGenome:Xenbase:XB-GENE-6251792
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    p7e4; btbd6; xbtbd6
    Summary
    Predicted to act upstream of or within neurogenesis. Predicted to be located in cytosol. Is expressed in cardiovascular system; musculoskeletal system; nervous system; pharyngeal arch; and primary germ layer. Orthologous to human BTBD6 (BTB domain containing 6). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See btbd6.L in Genome Data Viewer
    Location:
    chromosome: 8L
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (92101190..92106889)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (77373636..77379710)

    Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene piggyBac transposable element-derived protein 4-like Neighboring gene uncharacterized LOC121396864 Neighboring gene BRF1 general transcription factor IIIB subunit L homeolog Neighboring gene protein phosphatase 1 regulatory subunit 36 L homeolog Neighboring gene heat shock protein family A (Hsp70) member 2 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Systematic screening and expression analysis of the head organizer genes in Xenopus embryos. Shibata M, et al. Dev Biol, 2001 Nov 15. PMID 11784032
    2. Xenopus BTBD6 and its Drosophila homologue lute are required for neuronal development. Bury FJ, et al. Dev Dyn, 2008 Nov. PMID 18855900
    3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Process Evidence Code Pubs
    acts_upstream_of_or_within neurogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    BTB/POZ domain-containing protein 6
    Names
    BTB domain protein 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001088719.1 → NP_001082188.1  BTB/POZ domain-containing protein 6

      See identical proteins and their annotated locations for NP_001082188.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ327672
      UniProtKB/Swiss-Prot
      Q2LE78
      UniProtKB/TrEMBL
      A0A974H898
      Related
      ENSXLAP00005051277.1, ENSXLAT00005052439.1
      Conserved Domains (4) summary
      smart00225
      Location:128 → 227
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00875
      Location:233 → 339
      BACK; BTB And C-terminal Kelch
      pfam00651
      Location:120 → 223
      BTB; BTB/POZ domain
      pfam08005
      Location:384 → 527
      PHR; PHR domain

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      92101190..92106889
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041571938.1 → XP_041427872.1  BTB/POZ domain-containing protein 6 isoform X1

      UniProtKB/TrEMBL
      A0A8J1LEB5, A8E625
      Conserved Domains (2) summary
      cd18349
      Location:66 → 174
      BTB_POZ_BTBD6; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 6 (BTBD6)
      cd18525
      Location:174 → 268
      BACK_BTBD6; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 6 (BTBD6)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2LE78.1 GenPept UniProtKB/Swiss-Prot:Q2LE78

    Gene LinkOut

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    Other Literature Sources
    Molecular Biology Databases
    Research Materials