|
| Status |
Public on Mar 14, 2022 |
| Title |
RNA-Sequencing Characterisation of the Renal Cortical Response to Diet-Induced Weight Loss and Medical Therapy in the Zucker Diabetic Sprague Dawley Rat Model of Diabetic Kidney Disease |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We report results from renal cortical transcriptomic analysis of responses to diet-induced weight loss plus medical therapy in the Zucker Diabetic Sprague Dawley (ZDSD) rat model of diabetic kidney disease.
|
| |
|
| Overall design |
3 study groups: Sprague Dawley rats, SHAM-operated Zucker Diabetic Sprague Dawley (ZDSD) rats, and ZDSD rats treated with diet-induced weight loss plus medical therapy (ramipril, metformin, liraglutide, rosuvastatin, fenofibrate).
|
| Web link |
https://pubmed.ncbi.nlm.nih.gov/36259366/
|
| |
|
| Contributor(s) |
Martin WP, le Roux CW, Docherty NG |
| Citation(s) |
36259366 |
| |
| Submission date |
Mar 17, 2021 |
| Last update date |
Mar 12, 2023 |
| Contact name |
William P. Martin |
| E-mail(s) |
liampvmartin1992@gmail.com, william.martin@ucd.ie
|
| Organization name |
University College Dublin
|
| Street address |
Diabetes Complications Research Centre, Conway Institute, University College Dublin
|
| City |
Dublin |
| State/province |
- Select State/Province - |
| ZIP/Postal code |
Dublin 4 |
| Country |
Ireland |
| |
|
| Platforms (1) |
| GPL25947 |
Illumina NovaSeq 6000 (Rattus norvegicus) |
|
| Samples (21)
|
|
| Relations |
| BioProject |
PRJNA715189 |
| SRA |
SRP311305 |
Less...
More...