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| Status |
Public on Apr 28, 2023 |
| Title |
RNA-seq of in vitro differentiated naïve and Th9 cells |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To investigate changes in gene expression over time, we differentiated Th9 cells in vitro from naïve T cells from human and murine sources, and followed them over an extended time course, during which they gained and then lost capacity for IL-9 production
We then performed gene expression profiling analysis using data obtained from RNA-seq in cells from 2 different human donors and from 2 mice at 4 time points.
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| |
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for d0 (naïve), d3, d4. and d8 Th9 cells (mouse) or d0 (naïve), d5, d8, and d15 Th9 cells (human)
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| |
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| Contributor(s) |
Schwartz DM, Son A |
| Citation(s) |
37106040 |
| |
| Submission date |
Jan 14, 2023 |
| Last update date |
Apr 28, 2023 |
| Contact name |
Daniella Schwartz |
| E-mail(s) |
Daniella.Schwartz@pitt.edu
|
| Organization name |
University of Pittsburgh
|
| Street address |
200 Lothrop St
|
| City |
Pittsburgh |
| State/province |
PA |
| ZIP/Postal code |
15216 |
| Country |
USA |
| |
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| Platforms (2) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (28)
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| This SubSeries is part of SuperSeries: |
| GSE222910 |
ATAC-seq, ChIP-seq and RNA-seq of in vitro differentiated naïve, Th1, and Th9 cells |
|
| Relations |
| BioProject |
PRJNA923819 |
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