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Status |
Public on Oct 25, 2016 |
Title |
Exogenous expression of Lox, Loxl1 and Loxl2 regulate gene expression in primary murine lung fibroblasts. |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Primary murine lung fibroblasts were transfected with either control (scrambled) or sequence-specific siRNA against Lysyl oxidase (Lox), Lysyl oxidase-like (Loxl1) or Lysyl oxidase-like 2 (Loxl2) genes. Cells were harvested 48 hours after the transfection. Multiple changes in gene expression were found in the corrected p values in this microarray study.
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Overall design |
Four control (scrambled), four siLox, four siLoxl1 and four siLoxl2 transfected samples were used for this microarray study.
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Contributor(s) |
Mižíková I, Morty RE |
Citation missing |
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Submission date |
Oct 24, 2016 |
Last update date |
Feb 02, 2018 |
Contact name |
Rory Morty |
Organization name |
MPI für Herz- und Lungenforschung
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Department |
W.G. Kerckhoff-Institut
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Street address |
Parkstr. 1
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City |
Bad Nauheim |
ZIP/Postal code |
61231 |
Country |
Germany |
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Platforms (1) |
GPL10787 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Probe Name version) |
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Samples (16)
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GSM2359128 |
primary lung fibroblasts_scr. RNA_rep.1 |
GSM2359129 |
primary lung fibroblasts_ scr. RNA_rep.2 |
GSM2359130 |
primary lung fibroblasts_ scr. RNA_rep.3 |
GSM2359131 |
primary lung fibroblasts_ scr. RNA_rep.4 |
GSM2359132 |
primary lung fibroblasts_siLox_rep.1 |
GSM2359133 |
primary lung fibroblasts_ siLox _rep.2 |
GSM2359134 |
primary lung fibroblasts_ siLox _rep.3 |
GSM2359135 |
primary lung fibroblasts_ siLox _rep.4 |
GSM2359136 |
primary lung fibroblasts_siLoxL1_rep.1 |
GSM2359137 |
primary lung fibroblasts_ siLoxL1 _rep.2 |
GSM2359138 |
primary lung fibroblasts_ siLoxL1 _rep.3 |
GSM2359139 |
primary lung fibroblasts_ siLoxL1 _rep.4 |
GSM2359140 |
primary lung fibroblasts_siLoxL2_rep.1 |
GSM2359141 |
primary lung fibroblasts_ siLoxL2 _rep.2 |
GSM2359142 |
primary lung fibroblasts_ siLoxL2 _rep.3 |
GSM2359143 |
primary lung fibroblasts_ siLoxL2 _rep.4 |
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Relations |
BioProject |
PRJNA350326 |