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Sample GSM27169 Query DataSets for GSM27169
Status Public on Nov 05, 2004
Title A263insGG_mut3b-
Sample type RNA
 
Source name INS-1 cell line #3b with non-induced HNF1b mutant A263insGG
Organism Rattus norvegicus
Extracted molecule total RNA
 
Description A rat insulinoma cell line (INS-1) was generated that contains a FRT site for FLP recombinase mediated site specific integration of specific genes. In addition, the line contains the tetracycline repressor allowing tetracycline (tet) induction of the introduced gene. By comparing the gene expression profiles of uninduced and tet-induced cells, target genes of introduced transcription factors can be identified. This entry corresponds to the RNA isolated from uninduced INS-1 cell line #3b containing MODY5 mutant A263insGG of hepatocyte nuclear factor-1b (HNF1b).
Keywords = INS-1
Keywords = beta-cell
Keywords = HNF1b
Keywords = A263insGG
Keywords = MODY5
Keywords = tetracycline
Keywords = FRT
 
Submission date Jul 21, 2004
Last update date May 27, 2005
Contact name Ludger Klein-Hitpass
E-mail(s) ludger.klein-hitpass@uni-essen.de
Phone +49 201 723 85552
Organization name Institut fuer Zellbiologie
Department Universitaetsklinikum
Lab BioChip Lab
Street address Virchowstr. 173
City Essen
ZIP/Postal code D-45122
Country Germany
 
Platform ID GPL341
Series (2)
GSE1590 Targets of HNF1b mutants in INS-1
GSE6428 HNF1b, HNF4a2 and HNF6 targets

Data table header descriptions
ID_REF
VALUE ‘signal’, a measure of the abundance of the transcript
ABS_CALL the call in an absolute analysis that indicates whether a transcript is reliably detected (Present, P) or not detected (Absent, A)
DETECTION P-VALUE p-value that indicates the significance level of the detection call

Data table
ID_REF VALUE ABS_CALL DETECTION P-VALUE
AFFX-BioB-5_at 248.3 P 0.00141
AFFX-BioB-M_at 530.5 P 0.00011
AFFX-BioB-3_at 156.8 P 0.002867
AFFX-BioC-5_at 664.8 P 0.00006
AFFX-BioC-3_at 385.8 P 0.000052
AFFX-BioDn-5_at 894.1 P 0.000581
AFFX-BioDn-3_at 3649.8 P 0.000225
AFFX-CreX-5_at 5939.6 P 0.000044
AFFX-CreX-3_at 11315.9 P 0.000044
AFFX-DapX-5_at 177.4 P 0.000081
AFFX-DapX-M_at 391.8 P 0.001593
AFFX-DapX-3_at 352.7 P 0.000258
AFFX-LysX-5_at 2904.2 P 0.000044
AFFX-LysX-M_at 4185.1 P 0.000044
AFFX-LysX-3_at 6057.1 P 0.000044
AFFX-PheX-5_at 6305.7 P 0.000044
AFFX-PheX-M_at 7352.3 P 0.000044
AFFX-PheX-3_at 7428.7 P 0.000044
AFFX-ThrX-5_at 1028.8 P 0.000044
AFFX-ThrX-M_at 1398.2 P 0.000044

Total number of rows: 15923

Table truncated, full table size 431 Kbytes.




Supplementary data files not provided

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