Zfp738 zinc finger protein 738 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zfp738provided by MGI
Official Full Name: zinc finger protein 738provided by MGI
Primary source: MGI:MGI:3040706
See related: Ensembl:ENSMUSG00000048280 AllianceGenome:MGI:3040706
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 3830402I07Rik; 6720487G11Rik
Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated; negative regulation of transposon integration; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to several human genes including ZNF91 (zinc finger protein 91). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in CNS E18 (RPKM 2.4), CNS E14 (RPKM 2.2) and 23 other tissues See more
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Genomic context

Location:: 13 B3; 13 34.66 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	13	NC_000079.7 (67815560..67831631, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	13	NC_000079.6 (67667441..67683512, complement)

Chromosome 13 - NC_000079.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: zinc finger protein 738

Names: Novel Zinc finger, C2H2 type containing protein (3830402I07Rik)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001001187.3 → NP_001001187.2 zinc finger protein 738

Status: VALIDATED

Source sequence(s)

BC082605, BY752525

Consensus CDS

CCDS36716.2

UniProtKB/TrEMBL

B8JJX8

Related

ENSMUSP00000121275.3, ENSMUST00000137496.10

Conserved Domains (5) summary

smart00349
Location:15 → 73

KRAB; krueppel associated box

COG5048
Location:257 → 642

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:485 → 505

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam01352
Location:15 → 54

KRAB; KRAB box

pfam13465
Location:497 → 522

zf-H2C2_2; Zinc-finger double domain