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    Spdye4c speedy/RINGO cell cycle regulator family, member E4C [ Mus musculus (house mouse) ]

    Gene ID: 241634, updated on 9-Aug-2024

    Summary

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    Official Symbol
    Spdye4cprovided by MGI
    Official Full Name
    speedy/RINGO cell cycle regulator family, member E4Cprovided by MGI
    Primary source
    MGI:MGI:2685201
    See related
    Ensembl:ENSMUSG00000074812 AllianceGenome:MGI:2685201
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm355; SpyB3; SpeedyB3
    Summary
    Predicted to enable protein kinase binding activity. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 5.1) See more
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    Genomic context

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    See Spdye4c in Genome Data Viewer
    Location:
    2 F1; 2 62.63 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (128433121..128443483)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (128591201..128601662)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 36203 Neighboring gene STARR-seq mESC enhancer starr_05648 Neighboring gene non-histone chromosomal protein HMG-17 pseudogene Neighboring gene predicted gene, 39929 Neighboring gene protein transport protein Sec61 subunit gamma pseudogene Neighboring gene anaphase promoting complex subunit 1 Neighboring gene STARR-positive B cell enhancer ABC_E4498

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Evolution of the Cdk-activator Speedy/RINGO in vertebrates. Chauhan S, et al. Cell Mol Life Sci, 2012 Nov. PMID 22763696, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    speedy/RINGO cell cycle regulator family, member E4C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310641.1 → NP_001297570.1  speedy/RINGO cell cycle regulator family, member E4C

      See identical proteins and their annotated locations for NP_001297570.1

      Status: VALIDATED

      Source sequence(s)
      JQ023159
      Consensus CDS
      CCDS79844.1
      UniProtKB/TrEMBL
      A2AQG6, I6XKQ3, J3KMS1
      Related
      ENSMUSP00000117916.3, ENSMUST00000155430.9
      Conserved Domains (1) summary
      pfam11357
      Location:207 → 335
      Spy1; Cell cycle regulatory protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      128433121..128443483
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017318199.3 → XP_017173688.1  speedy/RINGO cell cycle regulator family, member E4C isoform X1

      UniProtKB/TrEMBL
      A2AQG6, I6XKQ3, J3KMS1
      Conserved Domains (1) summary
      pfam11357
      Location:207 → 335
      Spy1; Cell cycle regulatory protein

    2. XM_017318198.2 → XP_017173687.1  speedy/RINGO cell cycle regulator family, member E4C isoform X1

      UniProtKB/TrEMBL
      A2AQG6, I6XKQ3, J3KMS1
      Conserved Domains (1) summary
      pfam11357
      Location:207 → 335
      Spy1; Cell cycle regulatory protein
    Nucleotide Protein Strain
    Heading Accession and Version

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