ADY3 Ady3p [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: ADY3
Official Full Name: Ady3p
Primary source: SGD:S000002398
Locus tag: YDL239C
See related: AllianceGenome:SGD:S000002398; FungiDB:YDL239C; VEuPathDB:YDL239C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Involved in ascospore wall assembly; ascospore-type prospore membrane formation; and mitochondrion inheritance. Located in peroxisome; prospore membrane leading edge; and spindle pole body. [provided by Alliance of Genome Resources, Nov 2024]
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Chromosome IV - NC_001136.10 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in ascospore wall assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in ascospore-type prospore membrane formation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cell division	IEA Inferred from Electronic Annotation more info
involved_in meiotic cell cycle	IEA Inferred from Electronic Annotation more info
involved_in mitochondrion inheritance	IGI Inferred from Genetic Interaction more info	PubMed
involved_in mitochondrion inheritance	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitotic chromosome condensation	IBA Inferred from Biological aspect of Ancestor more info
involved_in sporulation resulting in formation of a cellular spore	IEA Inferred from Electronic Annotation more info
involved_in sporulation resulting in formation of a cellular spore	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chromatin	IBA Inferred from Biological aspect of Ancestor more info
is_active_in condensed chromosome	IBA Inferred from Biological aspect of Ancestor more info
part_of condensin complex	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in peroxisome	IDA Inferred from Direct Assay more info	PubMed
located_in prospore membrane	IDA Inferred from Direct Assay more info	PubMed
located_in prospore membrane	IEA Inferred from Electronic Annotation more info
located_in prospore membrane leading edge	HDA more info	PubMed
located_in prospore membrane leading edge	IDA Inferred from Direct Assay more info	PubMed
located_in spindle pole body	IDA Inferred from Direct Assay more info	PubMed
located_in spindle pole body	IEA Inferred from Electronic Annotation more info
located_in spindle pole body	IPI Inferred from Physical Interaction more info	PubMed

NP_010042.2

Protein required for spore wall formation; subunit of leading edge protein (LEP) complex (Ssp1-Ady3-Don1-Irc10) that forms ring-like structure at leading edge of prospore membrane during meiosis II; mediates assembly of LEP complex, formation of ring-like structure via interaction with spindle pole body components, and prospore membrane maturation; also detected in peroxisomes; potentially phosphorylated by Cdc28p; ADY3 has a paralog, CNM67, that arose from the whole genome duplication

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