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    vir-1 virus-induced RNA 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34652, updated on 10-May-2024

    Summary

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    Official Symbol
    vir-1provided by FlyBase
    Official Full Name
    virus-induced RNA 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0043841
    Locus tag
    Dmel_CG31764
    See related
    AllianceGenome:FB:FBgn0043841
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BEST:GH02216; CG15493; CG31764; CG5453; Dmel\CG31764; Vir-1; vir1; Vir1
    Summary
    Involved in defense response to virus. Is expressed in several structures, including embryonic/larval nervous system; embryonic/larval oenocyte; embryonic/larval posterior spiracle; presumptive embryonic/larval system; and ventral midline of embryo. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See vir-1 in Genome Data Viewer
    Location:
    33E3-33E4; 2-46 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (12403270..12423439, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (12403270..12423439, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene bruno 2 Neighboring gene uncharacterized protein Neighboring gene Polycystic kidney disease 2 Neighboring gene uncharacterized protein Neighboring gene Fam92

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nora Virus VP4b and ORF1 Circulate in Hemolymph of Infected D. melanogaster with Coordinate Expression of Vago and Vir-1. Macke A, et al. Vaccines (Basel), 2020 Aug 31. PMID 32878003, Free PMC Article
    2. Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila. Galiana-Arnoux D, et al. Nat Immunol, 2006 Jun. PMID 16554838
    3. Induction of host defence responses by Drosophila C virus. Hedges LM, et al. J Gen Virol, 2008 Jun. PMID 18474566
    4. DIP1 plays an antiviral role against DCV infection in Drosophila melanogaster. Zhang Q, et al. Biochem Biophys Res Commun, 2015 May 1. PMID 25770426
    5. Interactive effects of social environment, age and sex on immune responses in Drosophila melanogaster. Leech T, et al. J Evol Biol, 2019 Oct. PMID 31313398

    See all (96) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in defense response to virus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    virus-induced RNA 1
    Names
    CG31764-PA
    CG31764-PB
    CG31764-PC
    CG31764-PD
    CG31764-PE
    CG31764-PG
    CG31764-PH
    vir-1-PA
    vir-1-PB
    vir-1-PC
    vir-1-PD
    vir-1-PE
    vir-1-PG
    vir-1-PH
    virus induced RNA-1
    virus-induced 1
    virus-induced RNA1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      12403270..12423439 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273483.1 → NP_001260412.1  virus-induced RNA 1, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260412.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PFQ2, Q8SZ36
      Conserved Domains (1) summary
      PTZ00121
      Location:263 → 391
      PTZ00121; MAEBL; Provisional

    2. NM_165011.3 → NP_723747.1  virus-induced RNA 1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723747.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8R1, Q8SZ36
      Related
      FBpp0079970

    3. NM_165010.3 → NP_723746.1  virus-induced RNA 1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723746.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8R1, Q8SZ36
      Related
      FBpp0079971

    4. NM_001259074.2 → NP_001246003.1  virus-induced RNA 1, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246003.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q3YBY4

    5. NM_001038812.2 → NP_001033901.1  virus-induced RNA 1, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033901.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q3YBY4

    6. NM_001259075.2 → NP_001246004.2  virus-induced RNA 1, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246004.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SXD5

    7. NM_205966.2 → NP_995688.1  virus-induced RNA 1, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995688.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SXD5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PFQ2 M9PFQ2
    Q0E8R1 Q0E8R1
    Q3YBY4 Q3YBY4
    Q8SXD5 Q8SXD5
    Q8SZ36 Q8SZ36

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