DTR1 Dtr1p [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: DTR1
Official Full Name: Dtr1p
Primary source: SGD:S000000384
Locus tag: YBR180W
See related: AllianceGenome:SGD:S000000384; FungiDB:YBR180W; VEuPathDB:YBR180W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables amine transmembrane transporter activity. Involved in amine transport; ascospore wall assembly; and transmembrane transport. Located in prospore membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Chromosome II - NC_001134.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Both the carboxyl transmembrane domain and the C-terminal tail of Dtr1 are important for Golgi complex-to-prospore membrane transport.
Title: Sorting signals within the Saccharomyces cerevisiae sporulation-specific dityrosine transporter, Dtr1p, C terminus promote Golgi-to-prospore membrane transport.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables amine transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables amine transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in amine transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in amine transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in ascospore wall assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in sporulation resulting in formation of a cellular spore	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cell periphery	HDA more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in prospore membrane	IDA Inferred from Direct Assay more info	PubMed
located_in prospore membrane	IEA Inferred from Electronic Annotation more info

NP_009739.1

Putative dityrosine transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; required for spore wall synthesis; sequence similarity to QDR1 and QDR3, and the triple mutant dtr1 qdr1 qdr3 exhibits reduced dityrosine fluorescence relative to the single mutants; expressed during sporulation

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The following sections contain reference sequences that belong to a specific genome build. Explain