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    PEX25 Pex25p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855991, updated on 1-Aug-2024

    Summary

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    Gene symbol
    PEX25
    Gene description
    Pex25p
    Primary source
    FungiDB:YPL112C
    Locus tag
    YPL112C
    See related
    SGD:S000006033; AllianceGenome:SGD:S000006033; VEuPathDB:YPL112C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in protein import into peroxisome matrix. Located in peroxisomal membrane. Colocalizes with peroxisome. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See PEX25 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (337436..338620, complement)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene GTPase-activating protein BEM3 Neighboring gene glyoxylate reductase Neighboring gene tRNA-Met Neighboring gene arginase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Increased peroxisome proliferation is associated with early yeast replicative ageing. Deb R, et al. Curr Genet, 2022 Apr. PMID 35220444
    2. A combined approach of quantitative interaction proteomics and live-cell imaging reveals a regulatory role for endoplasmic reticulum (ER) reticulon homology proteins in peroxisome biogenesis. David C, et al. Mol Cell Proteomics, 2013 Sep. PMID 23689284, Free PMC Article
    3. A subtle interplay between three Pex11 proteins shapes de novo formation and fission of peroxisomes. Huber A, et al. Traffic, 2012 Jan. PMID 21951626, Free PMC Article
    4. Conserved function of pex11p and the novel pex25p and pex27p in peroxisome biogenesis. Rottensteiner H, et al. Mol Biol Cell, 2003 Oct. PMID 14517338, Free PMC Article
    5. Pex11-related proteins in peroxisome dynamics: a role for the novel peroxin Pex27p in controlling peroxisome size and number in Saccharomyces cerevisiae. Tam YY, et al. Mol Biol Cell, 2003 Oct. PMID 14517321, Free PMC Article

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in peroxisome fission IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in peroxisome organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in peroxisome organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein import into peroxisome matrix IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in peroxisomal membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in peroxisomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Pex25p
    NP_015213.1
    • Peripheral peroxisomal membrane peroxin; required for the regulation of peroxisome size and maintenance, recruits GTPase Rho1p to peroxisomes, induced by oleate, interacts with Pex27p; PEX25 has a paralog, PEX27, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      337436..338620 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183926.1 → NP_015213.1  TPA: Pex25p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015213.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3Q5, Q02969, Q6B2A9
      UniProtKB/TrEMBL
      B3LKW1, C7GJ66, C8ZIR8, G2WP69, N1P1J7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q02969.1

    Gene LinkOut

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