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    pgp phosphoglycolate phosphatase [ Danio rerio (zebrafish) ]

    Gene ID: 792824, updated on 12-Sep-2024

    Summary

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    Official Symbol
    pgpprovided by ZNC
    Official Full Name
    phosphoglycolate phosphataseprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-6240
    See related
    Ensembl:ENSDARG00000029695 AllianceGenome:ZFIN:ZDB-GENE-030131-6240
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb241; sb:cb241; zgc:56011; wu:fb92c03; wu:fi40b02
    Summary
    Predicted to enable glycerol-3-phosphatase activity. Predicted to be active in cytoplasm. Is expressed in adaxial cell; otic placode; and somite. Orthologous to human PGP (phosphoglycolate phosphatase). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See pgp in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (18565553..18568847, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (18443679..18446973, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene meiosis specific with OB-fold Neighboring gene MTOR associated protein, LST8 homolog (S. cerevisiae) Neighboring gene BRICHOS domain containing 5 Neighboring gene zinc finger DHHC-type palmitoyltransferase 4 Neighboring gene glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Ablation of Mto1 in zebrafish exhibited hypertrophic cardiomyopathy manifested by mitochondrion RNA maturation deficiency. Zhang Q, et al. Nucleic Acids Res, 2021 May 7. PMID 33836087, Free PMC Article
    2. Dhrs3a regulates retinoic acid biosynthesis through a feedback inhibition mechanism. Feng L, et al. Dev Biol, 2010 Feb 1. PMID 19874812, Free PMC Article
    3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC56011

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables glycerol-1-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycerol-3-phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphoglycolate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    glycerol-3-phosphate phosphatase
    NP_997891.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212726.2 → NP_997891.2  glycerol-3-phosphate phosphatase

      Status: VALIDATED

      Source sequence(s)
      CT009714
      UniProtKB/TrEMBL
      A0A8M1PI24, F1QGU0
      Related
      ENSDARP00000039692.6, ENSDART00000039693.7
      Conserved Domains (3) summary
      TIGR01452
      Location:21 → 300
      PGP_euk; phosphoglycolate/pyridoxal phosphate phosphatase family
      pfam13242
      Location:217 → 299
      Hydrolase_like; HAD-hyrolase-like
      pfam13344
      Location:24 → 125
      Hydrolase_6; Haloacid dehalogenase-like hydrolase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      18565553..18568847 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394835.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      531937..535353 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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