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    tmem35 transmembrane protein 35 [ Danio rerio (zebrafish) ]

    Gene ID: 791920, updated on 2-Nov-2024

    Summary

    Official Symbol
    tmem35provided by ZNC
    Official Full Name
    transmembrane protein 35provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030815-1
    See related
    Ensembl:ENSDARG00000052567 AllianceGenome:ZFIN:ZDB-GENE-030815-1
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    Xp18; tmem35a; flj14084; wu:fc41e12; zgc:110832
    Summary
    Predicted to enable acetylcholine receptor regulator activity. Predicted to be involved in chaperone-mediated protein complex assembly and positive regulation of protein localization to cell surface. Predicted to be located in cytoplasmic vesicle; endoplasmic reticulum membrane; and peroxisomal membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human TMEM35A (transmembrane protein 35A). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See tmem35 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (41279520..41285392, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (40912266..40918138, complement)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene dystrophin related protein 2 Neighboring gene centromere protein I Neighboring gene ADP-ribosylation factor-like 13A Neighboring gene XK related X-linked

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC110832

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables acetylcholine receptor regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in chaperone-mediated protein complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in chaperone-mediated protein complex assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of protein localization to cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of protein localization to cell surface ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in peroxisomal membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    novel acetylcholine receptor chaperone
    Names
    transmembrane protein 35A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014313.2NP_001014335.2  novel acetylcholine receptor chaperone

      Status: VALIDATED

      Source sequence(s)
      CR354605
      UniProtKB/TrEMBL
      A0A8M1N4V6, F1QZJ9
      Related
      ENSDARP00000117700.1, ENSDART00000147389.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      41279520..41285392 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)