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    RPL26B ribosomal 60S subunit protein L26B [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852922, updated on 29-Jun-2024

    Summary

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    Gene symbol
    RPL26B
    Gene description
    ribosomal 60S subunit protein L26B
    Primary source
    FungiDB:YGR034W
    Locus tag
    YGR034W
    See related
    SGD:S000003266; AllianceGenome:SGD:S000003266; VEuPathDB:YGR034W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables RNA binding activity. A structural constituent of ribosome. Involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 11. Orthologous to human RPL26 (ribosomal protein L26) and RPL26L1 (ribosomal protein L26 like 1). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RPL26B in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    2
    Sequence:
    Chromosome: VII; NC_001139.9 (555812..556672)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene 1,3-beta-glucan synthase GSC2 Neighboring gene Tim21p Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Saccharomyces cerevisiae ribosomal protein L26 is not essential for ribosome assembly and function. Babiano R, et al. Mol Cell Biol, 2012 Aug. PMID 22688513, Free PMC Article
    2. The Modular Adaptive Ribosome. Yadav A, et al. PLoS One, 2016. PMID 27812193, Free PMC Article
    3. Specialized ribosomes and specific ribosomal protein paralogs control translation of mitochondrial proteins. Segev N, et al. J Cell Biol, 2018 Jan 2. PMID 29118025, Free PMC Article
    4. Proximity of 5.8 S RNA-binding proteins and A-site proteins in yeast ribosomes inferred from cross-linking. Lee JC, et al. J Biol Chem, 1984 Aug 25. PMID 6432786
    5. Ribosomal proteins produced in excess are degraded by the ubiquitin-proteasome system. Sung MK, et al. Mol Biol Cell, 2016 Sep 1. PMID 27385339, Free PMC Article

    See all (76) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Saccharomyces cerevisiae ribosomal protein L26 is not essential for ribosome assembly and function
      Title: Saccharomyces cerevisiae ribosomal protein L26 is not essential for ribosome assembly and function.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cytoplasmic translation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in ribosomal large subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in intracellular organelle IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of protein-containing complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L26B
    NP_011548.2
    • Ribosomal 60S subunit protein L26B; binds to 5.8S rRNA; non-essential even when paralog is also deleted; deletion has minimal affections on ribosome biosynthesis; homologous to mammalian ribosomal protein L26 and bacterial L24; RPL26B has a paralog, RPL26A, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      555812..556672
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181163.1 → NP_011548.2  TPA: ribosomal 60S subunit protein L26B [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011548.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VUH0, P53221, Q06HN2, Q45U50
      UniProtKB/TrEMBL
      A7A1M3, B3RHL4, C7GRX0, C8Z8S9, G2WJG3, N1P9U7
      Conserved Domains (1) summary
      pfam16906
      Location:9 → 122
      Ribosomal_L26; Ribosomal proteins L26 eukaryotic, L24P archaeal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53221.2

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