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    ATP10 Atp10p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851109, updated on 1-Aug-2024

    Summary

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    Gene symbol
    ATP10
    Gene description
    Atp10p
    Primary source
    FungiDB:YLR393W
    Locus tag
    YLR393W
    See related
    SGD:S000004385; AllianceGenome:SGD:S000004385; VEuPathDB:YLR393W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables unfolded protein binding activity. Involved in mitochondrial proton-transporting ATP synthase complex assembly. Located in mitochondrial inner membrane. Is integral component of mitochondrial membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See ATP10 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (907079..907918)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Ccw14p Neighboring gene Art10p Neighboring gene SUMO ligase CST9 Neighboring gene cytochrome c oxidase subunit VIII

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ATP10, a yeast nuclear gene required for the assembly of the mitochondrial F1-F0 complex. Ackerman SH, et al. J Biol Chem, 1990 Jun 15. PMID 2141026
    2. Atp23p and Atp10p coordinate to regulate the assembly of yeast mitochondrial ATP synthase. Yang G, et al. FASEB J, 2021 Jun. PMID 33956347
    3. Cytochrome c release and mitochondria involvement in programmed cell death induced by acetic acid in Saccharomyces cerevisiae. Ludovico P, et al. Mol Biol Cell, 2002 Aug. PMID 12181332, Free PMC Article
    4. A single amino acid change in subunit 6 of the yeast mitochondrial ATPase suppresses a null mutation in ATP10. Paul MF, et al. J Biol Chem, 2000 Sep 22. PMID 10867012
    5. Prohibitins interact genetically with Atp23, a novel processing peptidase and chaperone for the F1Fo-ATP synthase. Osman C, et al. Mol Biol Cell, 2007 Feb. PMID 17135288, Free PMC Article

    See all (54) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables unfolded protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial proton-transporting ATP synthase complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial proton-transporting ATP synthase complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitochondrial proton-transporting ATP synthase complex assembly IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial inner membrane IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in mitochondrial membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Atp10p
    NP_013497.1
    • Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase; mitochondrial inner membrane protein; interacts genetically with ATP6

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      907079..907918
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182281.1 → NP_013497.1  TPA: Atp10p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013497.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZ28, P18496, Q06020
      UniProtKB/TrEMBL
      A7A1R8, B3RHQ8, C7GXJ7, C8ZE02, G2WJK8, N1NYS5
      Conserved Domains (1) summary
      pfam05176
      Location:25 → 274
      ATP-synt_10; ATP10 protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P18496.2

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