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    CSA1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856304, updated on 11-Sep-2024

    Summary

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    Official Symbol
    CSA1
    Primary source
    SGD:S000006378
    Locus tag
    YPR174C
    See related
    AllianceGenome:SGD:S000006378; FungiDB:YPR174C; VEuPathDB:YPR174C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Acts upstream of or within positive regulation of protein localization to spindle pole body. Located in nuclear envelope and spindle pole body. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (888043..888708, complement)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene pyridoxal 5'-phosphate synthase Neighboring gene AAA family ATPase VPS4 Neighboring gene DNA polymerase epsilon noncatalytic subunit Neighboring gene Rab geranylgeranyltransferase BET2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Long 3'-UTRs target wild-type mRNAs for nonsense-mediated mRNA decay in Saccharomyces cerevisiae. Kebaara BW, et al. Nucleic Acids Res, 2009 May. PMID 19270062, Free PMC Article
    2. Proline-Rich Motifs Control G2-CDK Target Phosphorylation and Priming an Anchoring Protein for Polo Kinase Localization. Örd M, et al. Cell Rep, 2020 Jun 16. PMID 32553169, Free PMC Article
    3. Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae. Philip J, et al. Elife, 2022 Feb 10. PMID 35142288, Free PMC Article
    4. Multisite phosphorylation networks as signal processors for Cdk1. Kõivomägi M, et al. Nat Struct Mol Biol, 2013 Dec. PMID 24186061, Free PMC Article
    5. Localization of proteins that are coordinately expressed with Cln2 during the cell cycle. Sundin BA, et al. Yeast, 2004 Jul 15. PMID 15282802

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of protein localization to spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nuclear membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear periphery HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in spindle pole body IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Csa1p
    NP_015500.1
    • hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery; potential Cdc28p substrate; binds phosphatidylinositols and phosphatidylethanolamine in a large-scale study; relative distribution to foci at the nuclear periphery increases upon DNA replication stress; YPR174C has a paralog, NBP1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      888043..888708 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184271.1 → NP_015500.1  TPA: Csa1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015500.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W4H5, Q06616
      UniProtKB/TrEMBL
      B3LKD4, C8ZJK3, N1P2H6
      Conserved Domains (1) summary
      pfam08537
      Location:94 → 221
      NBP1; Fungal Nap binding protein NBP1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06616.1

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