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    zyg11l zyg-11 family member, cell cycle regulator, like [ Danio rerio (zebrafish) ]

    Gene ID: 567429, updated on 27-Mar-2024

    Summary

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    Official Symbol
    zyg11lprovided by ZNC
    Official Full Name
    zyg-11 family member, cell cycle regulator, likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5941
    See related
    Ensembl:ENSDARG00000101799 AllianceGenome:ZFIN:ZDB-GENE-030131-5941
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fi26e04; wu:fi26e04; si:ch1073-82l19.1
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of Cul2-RING ubiquitin ligase complex. Orthologous to human ZYG11A (zyg-11 family member A, cell cycle regulator) and ZYG11B (zyg-11 family member B, cell cycle regulator). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See zyg11l in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (2927463..2957459, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (3085574..3115567, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2B, subunit 5 epsilon Neighboring gene leucine-rich repeat-containing protein 38-like Neighboring gene phosphoinositide-3-kinase, regulatory subunit 3a (gamma) Neighboring gene intracisternal A particle-promoted polypeptide

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Functional and genetic analyses of ZYG11B provide evidences for its involvement in OAVS. Tingaud-Sequeira A, et al. Mol Genet Genomic Med, 2020 Oct. PMID 32738032, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    part_of Cul2-RING ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    protein zyg-11 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      2927463..2957459 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009296723.2 → XP_009294998.1  protein zyg-11 homolog isoform X3

      UniProtKB/TrEMBL
      A0A8M3AY84
      Conserved Domains (4) summary
      COG4886
      Location:98 → 269
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00020
      Location:476 → 578
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      cd00116
      Location:70 → 257
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00034
      Location:70 → 98
      LRR_AMN1; leucine-rich repeat [structural motif]

    2. XM_009296721.2 → XP_009294996.1  protein zyg-11 homolog isoform X2

      UniProtKB/TrEMBL
      A0A8M3ANH3
      Conserved Domains (4) summary
      COG4886
      Location:98 → 269
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00020
      Location:504 → 606
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      cd00116
      Location:70 → 257
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00034
      Location:70 → 98
      LRR_AMN1; leucine-rich repeat [structural motif]

    3. XM_690724.8 → XP_695816.5  protein zyg-11 homolog isoform X1

      UniProtKB/TrEMBL
      A0A0R4IGL5, A0A8N7TEE8
      Related
      ENSDARP00000134209.1, ENSDART00000162505.2
      Conserved Domains (4) summary
      COG4886
      Location:98 → 269
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00020
      Location:505 → 607
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      cd00116
      Location:70 → 257
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00034
      Location:70 → 98
      LRR_AMN1; leucine-rich repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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