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    BBP1 Bbp1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855820, updated on 17-May-2024

    Summary

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    Gene symbol
    BBP1
    Gene description
    Bbp1p
    Primary source
    FungiDB:YPL255W
    Locus tag
    YPL255W
    See related
    SGD:S000006176; AllianceGenome:SGD:S000006176; VEuPathDB:YPL255W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables structural molecule activity. Involved in protein localization to spindle pole body and spindle pole body duplication. Located in central plaque of spindle pole body. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See BBP1 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (67725..68882)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene cyclin CLN2 Neighboring gene Hfi1p Neighboring gene Vik1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Yeast mutants that produce a novel type of ascus containing asci instead of spores. Xue Z, et al. Genetics, 1996 Nov. PMID 8913743, Free PMC Article
    2. Requirement for Bbp1p in the proper mitotic functions of Cdc5p in Saccharomyces cerevisiae. Park CJ, et al. Mol Biol Cell, 2004 Apr. PMID 14767068, Free PMC Article
    3. Specific coiled-coil interactions contribute to a global model of the structure of the spindle pole body. Zizlsperger N, et al. J Struct Biol, 2010 May. PMID 20139001
    4. The Bbp1p-Mps2p complex connects the SPB to the nuclear envelope and is essential for SPB duplication. Schramm C, et al. EMBO J, 2000 Feb 1. PMID 10654940, Free PMC Article
    5. Yeast centrosome components form a noncanonical LINC complex at the nuclear envelope insertion site. Chen J, et al. J Cell Biol, 2019 May 6. PMID 30862629, Free PMC Article

    See all (49) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural molecule activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein localization to spindle pole body IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in spindle pole body duplication IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in spindle pole body duplication IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in central plaque of spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spindle pole body IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Bbp1p
    NP_015068.1
    • Protein required for the spindle pole body (SPB) duplication; localizes at the cytoplasmic side of the central plaque periphery of the SPB; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      67725..68882
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184069.1 → NP_015068.1  TPA: Bbp1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015068.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3LKH7, B5VST2, C8ZIC3, D6W3B6, E7KV71, E7QLJ6, Q12365
      UniProtKB/TrEMBL
      A0A8H4BUR5, N1NW40
      Conserved Domains (2) summary
      pfam15271
      Location:10 → 170
      BBP1_N; Spindle pole body component BBP1, Mps2-binding protein
      pfam15272
      Location:218 → 383
      BBP1_C; Spindle pole body component BBP1, C-terminal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12365.1

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