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    SSH1 slingshot protein phosphatase 1 [ Homo sapiens (human) ]

    Gene ID: 54434, updated on 14-Nov-2024

    Summary

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    Official Symbol
    SSH1provided by HGNC
    Official Full Name
    slingshot protein phosphatase 1provided by HGNC
    Primary source
    HGNC:HGNC:30579
    See related
    Ensembl:ENSG00000084112 MIM:606778; AllianceGenome:HGNC:30579
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SSH1L
    Summary
    The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
    Expression
    Ubiquitous expression in gall bladder (RPKM 6.2), endometrium (RPKM 5.8) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See SSH1 in Genome Data Viewer
    Location:
    12q24.11
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (108778191..108857583, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (108752810..108832275, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (109171967..109251359, complement)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene coronin 1C Neighboring gene RNA, U7 small nuclear 169 pseudogene Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:109085249-109085930 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:109085931-109086612 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr12:109087326-109087838 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6976 Neighboring gene Sharpr-MPRA regulatory region 4572 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:109095295-109095827 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6977 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:109108143-109108833 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:109108834-109109524 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr12:109109525-109110214 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4831 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:109125165-109125968 Neighboring gene uncharacterized LOC105369969 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:109128377-109128878 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4833 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:109164153-109164653 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6978 Neighboring gene small nucleolar RNA SNORA40 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:109185940-109186440 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:109187809-109188319 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:109192141-109192642 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr12:109195372-109196325 Neighboring gene uncharacterized LOC101929204 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr12:109199370-109200569 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:109207967-109208570 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6979 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:109221436-109222007 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6980 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr12:109231638-109232837 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:109232831-109233432 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4834 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4835 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4836 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr12:109247741-109248940 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:109250055-109250556 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6982 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4837 Neighboring gene microRNA 619 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:109273628-109274245 Neighboring gene MPRA-validated peak1937 silencer Neighboring gene uncharacterized LOC124903011 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:109300977-109301477 Neighboring gene NANOG hESC enhancer GRCh37_chr12:109311835-109312350 Neighboring gene D-amino acid oxidase Neighboring gene RNA, U6 small nuclear 361, pseudogene Neighboring gene SV2 related protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Dysregulated expression of slingshot protein phosphatase 1 (SSH1) disrupts circadian rhythm and WNT signaling associated to hepatocellular carcinoma pathogenesis.
      Title: Dysregulated expression of slingshot protein phosphatase 1 (SSH1) disrupts circadian rhythm and WNT signaling associated to hepatocellular carcinoma pathogenesis.
    2. Slingshot homolog-1-mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer's disease.
      Title: Slingshot homolog-1-mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer's disease.
    3. SSH1 promotes progression of intrahepatic cholangiocarcinoma via p38 MAPK-CXCL8 axis.
      Title: SSH1 promotes progression of intrahepatic cholangiocarcinoma via p38 MAPK-CXCL8 axis.
    4. Slingshot homolog-1 amplifies mitochondrial abnormalities by distinctly impairing health and clearance of mitochondria.
      Title: Slingshot homolog-1 amplifies mitochondrial abnormalities by distinctly impairing health and clearance of mitochondria.
    5. Role of SSH1 in colorectal cancer prognosis and tumor progression.
      Title: Role of SSH1 in colorectal cancer prognosis and tumor progression.
    6. genetic variants at the genes SSH1 and ST8SIA1 were related to the genetic predisposition to early-onset periodontitis that is in part triggered by smoking
      Title: Smoking Modifies the Genetic Risk for Early-Onset Periodontitis.
    7. SSH1 binds to gelsolin via actin filaments in the cytosolic fraction. Gelsolin promoted solubilization of actin filaments and SSH1 in cell-free assays and in cultured cells.
      Title: Activation of cytosolic Slingshot-1 phosphatase by gelsolin-generated soluble actin filaments.
    8. the N-terminal PH-like domain plays a critical role in F-actin binding and F-actin-mediated activation of the cofilin-phosphatase activity of SSH1
      Title: A pleckstrin homology-like domain is critical for F-actin binding and cofilin-phosphatase activity of Slingshot-1.
    9. Results reveal that SSH1L is upregulated in a subset of PCs and that the SSH1L/cofilin-1 signal pathway is associated positively in PC with cell migration.
      Title: Cofilin-phosphatase slingshot-1L (SSH1L) is over-expressed in pancreatic cancer (PC) and contributes to tumor cell migration.
    10. Authors show that viral penetration-induced calcium release facilitated herpes simplex virus type 1 intracellular trafficking through activating slingshot 1 (SSH), a phosphatase regulating actin filament dynamics.
      Title: Calcium-signal facilitates herpes simplex virus type 1 nuclear transport through slingshot 1 and calpain-1 activation.
    Submit: New GeneRIF Correction See all GeneRIFs (33)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See Variation Viewer (GRCh37.p13)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ21928, FLJ38102, KIAA1298

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables MAP kinase serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables actin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables actin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables calmodulin-dependent protein phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H2AXS140 phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H2AXY142 phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables non-membrane spanning protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphoprotein phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphoprotein phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphoprotein phosphatase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein tyrosine phosphatase activity, metal-dependent IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in actin cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to ATP IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in excitatory chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of actin filament polymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of AMPA glutamate receptor clustering IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of excitatory postsynaptic potential IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of synaptic plasticity IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of vascular associated smooth muscle cell migration IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein dephosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of protein metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cleavage furrow IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in growth cone IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in lamellipodium IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein phosphatase Slingshot homolog 1
    Names
    SSH-like protein 1
    hSSH-1L
    slingshot homolog 1
    NP_001154802.1
    NP_001154803.1
    NP_061857.3
    XP_005269041.1
    XP_005269042.1
    XP_011536799.1
    XP_011536801.1
    XP_011536802.1
    XP_011536803.1
    XP_016874980.1
    XP_047284977.1
    XP_047284978.1
    XP_047284979.1
    XP_047284980.1
    XP_047284981.1
    XP_047284982.1
    XP_054228292.1
    XP_054228293.1
    XP_054228294.1
    XP_054228295.1
    XP_054228296.1
    XP_054228297.1
    XP_054228298.1
    XP_054228299.1
    XP_054228300.1
    XP_054228301.1
    XP_054228302.1
    XP_054228303.1
    XP_054228304.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029846.2 RefSeqGene

      Range
      5000..84392
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001161330.2 → NP_001154802.1  protein phosphatase Slingshot homolog 1 isoform 2

      See identical proteins and their annotated locations for NP_001154802.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs at the 3' end compared to variant 1. This results in a shorter isoform (2, also known as SSH-1S) with a distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AB072356, BP363810
      Consensus CDS
      CCDS55882.1
      UniProtKB/Swiss-Prot
      Q8WYL5
      Related
      ENSP00000448824.1, ENST00000551165.5
      Conserved Domains (3) summary
      cd11652
      Location:3 → 237
      SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
      cd00127
      Location:308 → 444
      DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
      pfam08766
      Location:252 → 303
      DEK_C; DEK C terminal domain

    2. NM_001161331.1 → NP_001154803.1  protein phosphatase Slingshot homolog 1 isoform 3

      See identical proteins and their annotated locations for NP_001154803.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) contains an alternative 5' terminal exon, and differs at the 3' end compared to variant 1. This results in a shorter isoform (3) with distinct N- and C-termini compared to isoform 1.
      Source sequence(s)
      AB072356, AK095421
      Consensus CDS
      CCDS53825.1
      UniProtKB/Swiss-Prot
      Q8WYL5
      Related
      ENSP00000326107.5, ENST00000326470.9
      Conserved Domains (3) summary
      cd11652
      Location:41 → 248
      SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
      cd00127
      Location:319 → 455
      DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
      pfam08766
      Location:263 → 314
      DEK_C; DEK C terminal domain

    3. NM_018984.4 → NP_061857.3  protein phosphatase Slingshot homolog 1 isoform 1

      See identical proteins and their annotated locations for NP_061857.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1, also known as SSH-1L). This isoform has been shown to be enzymatically active (PMID:11832213).
      Source sequence(s)
      AB072355, AC087893, AI621348, BC020243, BP363810
      Consensus CDS
      CCDS9121.1
      UniProtKB/Swiss-Prot
      Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q8WYL5, Q9P2P8
      Related
      ENSP00000315713.5, ENST00000326495.10
      Conserved Domains (3) summary
      cd11652
      Location:3 → 237
      SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
      cd00127
      Location:308 → 444
      DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
      pfam08766
      Location:252 → 303
      DEK_C; DEK C terminal domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      108778191..108857583 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047429022.1 → XP_047284978.1  protein phosphatase Slingshot homolog 1 isoform X4

    2. XM_005268985.3 → XP_005269042.1  protein phosphatase Slingshot homolog 1 isoform X7

      See identical proteins and their annotated locations for XP_005269042.1

      Conserved Domains (3) summary
      cd11652
      Location:1 → 157
      SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
      cd00127
      Location:228 → 364
      DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
      pfam08766
      Location:172 → 223
      DEK_C; DEK C terminal domain

    3. XM_047429023.1 → XP_047284979.1  protein phosphatase Slingshot homolog 1 isoform X6

    4. XM_047429021.1 → XP_047284977.1  protein phosphatase Slingshot homolog 1 isoform X4

    5. XM_005268984.5 → XP_005269041.1  protein phosphatase Slingshot homolog 1 isoform X2

      Conserved Domains (3) summary
      cd11652
      Location:11 → 237
      SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
      cd00127
      Location:308 → 444
      DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
      pfam08766
      Location:252 → 303
      DEK_C; DEK C terminal domain

    6. XM_011538499.2 → XP_011536801.1  protein phosphatase Slingshot homolog 1 isoform X5

      Conserved Domains (3) summary
      cd11652
      Location:41 → 248
      SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
      pfam08766
      Location:263 → 314
      DEK_C; DEK C terminal domain
      cl21483
      Location:320 → 401
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

    7. XM_011538497.2 → XP_011536799.1  protein phosphatase Slingshot homolog 1 isoform X1

      Conserved Domains (3) summary
      cd11652
      Location:41 → 248
      SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
      cd00127
      Location:319 → 455
      DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
      pfam08766
      Location:263 → 314
      DEK_C; DEK C terminal domain

    8. XM_047429024.1 → XP_047284980.1  protein phosphatase Slingshot homolog 1 isoform X8

    9. XM_017019491.3 → XP_016874980.1  protein phosphatase Slingshot homolog 1 isoform X3

    10. XM_011538501.4 → XP_011536803.1  protein phosphatase Slingshot homolog 1 isoform X7

      See identical proteins and their annotated locations for XP_011536803.1

      Conserved Domains (3) summary
      cd11652
      Location:1 → 157
      SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
      cd00127
      Location:228 → 364
      DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
      pfam08766
      Location:172 → 223
      DEK_C; DEK C terminal domain

    11. XM_011538500.4 → XP_011536802.1  protein phosphatase Slingshot homolog 1 isoform X7

      See identical proteins and their annotated locations for XP_011536802.1

      Conserved Domains (3) summary
      cd11652
      Location:1 → 157
      SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
      cd00127
      Location:228 → 364
      DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
      pfam08766
      Location:172 → 223
      DEK_C; DEK C terminal domain

    12. XM_047429025.1 → XP_047284981.1  protein phosphatase Slingshot homolog 1 isoform X9

    13. XM_047429026.1 → XP_047284982.1  protein phosphatase Slingshot homolog 1 isoform X10

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      108752810..108832275 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054372321.1 → XP_054228296.1  protein phosphatase Slingshot homolog 1 isoform X4

    2. XM_054372326.1 → XP_054228301.1  protein phosphatase Slingshot homolog 1 isoform X7

    3. XM_054372323.1 → XP_054228298.1  protein phosphatase Slingshot homolog 1 isoform X6

    4. XM_054372320.1 → XP_054228295.1  protein phosphatase Slingshot homolog 1 isoform X4

    5. XM_054372318.1 → XP_054228293.1  protein phosphatase Slingshot homolog 1 isoform X2

    6. XM_054372322.1 → XP_054228297.1  protein phosphatase Slingshot homolog 1 isoform X5

    7. XM_054372317.1 → XP_054228292.1  protein phosphatase Slingshot homolog 1 isoform X1

    8. XM_054372327.1 → XP_054228302.1  protein phosphatase Slingshot homolog 1 isoform X8

    9. XM_054372319.1 → XP_054228294.1  protein phosphatase Slingshot homolog 1 isoform X3

    10. XM_054372325.1 → XP_054228300.1  protein phosphatase Slingshot homolog 1 isoform X7

    11. XM_054372324.1 → XP_054228299.1  protein phosphatase Slingshot homolog 1 isoform X7

    12. XM_054372328.1 → XP_054228303.1  protein phosphatase Slingshot homolog 1 isoform X9

    13. XM_054372329.1 → XP_054228304.1  protein phosphatase Slingshot homolog 1 isoform X10

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8WYL5.2 GenPept UniProtKB/Swiss-Prot:Q8WYL5

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