ERLNC1 estrogen receptor responsive lncRNA 1 [Homo sapiens (human)] - Gene

Summary

Official Symbol: ERLNC1provided by HGNC
Official Full Name: estrogen receptor responsive lncRNA 1provided by HGNC
Primary source: HGNC:HGNC:41109
See related: Ensembl:ENSG00000230550 AllianceGenome:HGNC:41109
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: ElncRNA1; TC0101441
Expression: Biased expression in liver (RPKM 7.1), testis (RPKM 6.6) and 9 other tissues See more
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Genomic context

Location:: 1q32.1

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	1	NC_000001.11 (204141408..204143009)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	1	NC_060925.1 (203405563..203407164)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	1	NC_000001.10 (204110536..204112137)

Chromosome 1 - NC_000001.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Analysis of Long Non-Coding RNA (lncRNA) UCA1, MALAT1, TC0101441, and H19 Expression in Endometriosis.
Title: Analysis of Long Non-Coding RNA (lncRNA) UCA1, MALAT1, TC0101441, and H19 Expression in Endometriosis.
High TC0101441 expression is associated with induction of epithelial-mesenchymal transition in epithelial ovarian cancer metastasis.
Title: Long noncoding RNA TC0101441 induces epithelial-mesenchymal transition in epithelial ovarian cancer metastasis by downregulating KiSS1.
Study provides the first evidence that E2 transcriptionally upregulates ElncRNA1 through the ERalpha-ERE pathway and that this novel E2-upregulated lncRNA has an oncogenic role in epithelial ovarian cancer (EOC) growth. The addition of ElncRNA1 to the E2-ERalpha-ERE signaling pathway may provide greater insight into the oestrogenic effects on EOC progression.
Title: ElncRNA1, a long non-coding RNA that is transcriptionally induced by oestrogen, promotes epithelial ovarian cancer cell proliferation.

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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General gene information

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NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.