McCune-Albright syndrome
- Synonyms
- Albright syndrome; Albright's Syndrome; Albright's disease; McCune-Albright syndrome, somatic, mosaic
- Modes of inheritance
- Not genetically inherited (Orphanet)
Summary
Excerpted from the GeneReview:- Full text of GeneReview (by section):
- Summary
- Diagnosis
- Clinical Characteristics
- Genetically Related (Allelic) Disorders
- Differential Diagnosis
- Management
- Genetic Counseling
- Resources
- Molecular Genetics
- Chapter Notes
- References
- Authors:
- Vivian Szymczuk
- Pablo Florenzano
- Luis F de Castro
- view full author information
Available tests
Check Related conditions for additional relevant tests.
Clinical features
Help- Abnormality of head or neck
- Facial asymmetry
Facial asymmetry
- MedGen UID: 266298
- Concept ID: C1306710
- Finding: Finding
Abnormality of head or neck
- Facial asymmetry
- Abnormality of the digestive system
- Intestinal polyposis
Intestinal polyposis
- MedGen UID: 219797
- Concept ID: C1257915
- Finding: Disease or Syndrome
Abnormality of the digestive system
- Pancreatic intraductal papillary-mucinous neoplasm
Pancreatic intraductal papillary-mucinous neoplasm
- MedGen UID: 1373306
- Concept ID: C4511687
- Finding: Neoplastic Process
Abnormality of the digestive system
- Intestinal polyposis
- Abnormality of the ear
- Hearing impairment
Hearing impairment
- MedGen UID: 235586
- Concept ID: C1384666
- Finding: Disease or Syndrome
Abnormality of the ear
- Hearing impairment
- Abnormality of the endocrine system
- Abnormal circulating aldosterone concentration
Abnormal circulating aldosterone concentration
- MedGen UID: 808216
- Concept ID: C0857898
- Finding: Finding
Abnormality of the endocrine system
- Abnormal circulating renin concentration
Abnormal circulating renin concentration
- MedGen UID: 866691
- Concept ID: C4021038
- Finding: Finding
Abnormality of the endocrine system
- Elevated circulating growth hormone concentration
Elevated circulating growth hormone concentration
- MedGen UID: 66732
- Concept ID: C0235986
- Finding: Finding
Abnormality of the endocrine system
- Hyperparathyroidism
Hyperparathyroidism
- MedGen UID: 6967
- Concept ID: C0020502
- Finding: Disease or Syndrome
Abnormality of the endocrine system
- Hyperthyroidism
Hyperthyroidism
- MedGen UID: 6972
- Concept ID: C0020550
- Finding: Disease or Syndrome
Abnormality of the endocrine system
- Increased circulating cortisol level
Increased circulating cortisol level
- MedGen UID: 871175
- Concept ID: C4025651
- Finding: Finding
Abnormality of the endocrine system
- Precocious puberty
Precocious puberty
- MedGen UID: 18752
- Concept ID: C0034013
- Finding: Disease or Syndrome
Abnormality of the endocrine system
- Abnormal circulating aldosterone concentration
- Abnormality of the eye
- Blindness
Blindness
- MedGen UID: 99138
- Concept ID: C0456909
- Finding: Disease or Syndrome
Abnormality of the eye
- Blindness
- Abnormality of the integument
- Large cafe-au-lait macules with irregular margins
Large cafe-au-lait macules with irregular margins
- MedGen UID: 870720
- Concept ID: C4025174
- Finding: Finding
Abnormality of the integument
- Large cafe-au-lait macules with irregular margins
- Abnormality of the musculoskeletal system
- Craniofacial hyperostosis
Craniofacial hyperostosis
- MedGen UID: 358122
- Concept ID: C1868085
- Finding: Finding
Abnormality of the musculoskeletal system
- Pathologic fracture
Pathologic fracture
- MedGen UID: 42095
- Concept ID: C0016663
- Finding: Pathologic Function
Abnormality of the musculoskeletal system
- Polyostotic fibrous dysplasia of bone
Polyostotic fibrous dysplasia of bone
- MedGen UID: 5180
- Concept ID: C0016065
- Finding: Neoplastic Process
Abnormality of the musculoskeletal system
- Sclerotic ilium
Sclerotic ilium
- MedGen UID: 1053980
- Concept ID: CN378015
- Finding: Finding
Abnormality of the musculoskeletal system
- Craniofacial hyperostosis
- Abnormality of the nervous system
- Increased circulating prolactin concentration
Increased circulating prolactin concentration
- MedGen UID: 1702649
- Concept ID: C5200994
- Finding: Finding
Abnormality of the nervous system
- Increased circulating prolactin concentration
- Constitutional symptom
- Bone pain
Bone pain
- MedGen UID: 57489
- Concept ID: C0151825
- Finding: Sign or Symptom
Constitutional symptom
- Bone pain
- Growth abnormality
- Acral overgrowth
Acral overgrowth
- MedGen UID: 1789172
- Concept ID: C1735881
- Finding: Disease or Syndrome
Growth abnormality
- Acral overgrowth
- Neoplasm
- Pituitary adenoma
Pituitary adenoma
- MedGen UID: 45933
- Concept ID: C0032000
- Finding: Neoplastic Process
Neoplasm
- Pituitary adenoma
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