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Hyper-IgM syndrome type 2

Synonyms
Hyper-IgM Immunodeficiency Syndrome, Type 2; Immunodeficiency with hyper IgM type 2

Summary

Hyper-IgM syndrome type 2 (HIGM2) is a rare immunodeficiency characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE, resulting in a profound susceptibility to bacterial infections. For a discussion of genetic heterogeneity of immunodeficiency with hyper-IgM, see HIGM1 (308230). [from OMIM]

Available tests

31 tests are in the database for this condition.

Check Related conditions for additional relevant tests.

Clinical tests (31 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

  • Also known as: AID, ARP2, CDA2, HEL-S-284, HIGM2, AICDA
    Summary: activation induced cytidine deaminase

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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