Pancreatic cancer, susceptibility to, 3

Synonyms: Pancreatic Cancer Susceptibility 3; Pancreatic cancer 3

Summary

Individuals with mutation in the PALB2 gene have an increased risk of developing pancreatic cancer. In addition, PALB2 variants increase susceptibility to several other cancers, e.g., familial breast-ovarian cancer (BROVCA5; 620422) (Jones et al., 2009; Yang et al., 2020). For background, phenotypic description, and a discussion of genetic heterogeneity of pancreatic carcinoma, see 260350. [from OMIM]

Available tests

95 tests are in the database for this condition.

Clinical tests (95 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

Associated genes Help
Genes reported to contribute to the condition.

PALB2
400 tests
Also known as: BROVCA5, FANCN, PNCA3, PALB2
Summary: partner and localizer of BRCA2

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Clinical resources

Molecular resources

Consumer resources

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