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GTR Home > Conditions/Phenotypes > Obesity due to leptin receptor gene deficiency

Obesity due to leptin receptor gene deficiency

Synonyms
Leptin receptor deficiency
Modes of inheritance
Autosomal recessive inheritance (Orphanet)

Summary

Leptin receptor deficiency is characterized by severe early-onset obesity, major hyperphagia, hypogonadotropic hypogonadism, and neuroendocrine/metabolic dysfunction (summary by Dehghani et al., 2018). [from OMIM]

Available tests

34 tests are in the database for this condition.

Check Related conditions for additional relevant tests.

Clinical tests (34 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

  • Also known as: CD295, LEP-R, LEPRD, OB-R, OBR, LEPR
    Summary: leptin receptor

Clinical features

Help
Imported from Human Phenotype Ontology (HPO)

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