Juvenile arthritis due to defect in LACC1

Synonyms: Juvenile arthritis

Summary

Juvenile arthritis (JUVAR) is characterized by onset in early childhood of symmetric arthritis in multiple joints, associated with a marked increase in inflammatory markers. Some patients exhibit systemic symptoms, including quotidian fever, erythematous rash, generalized lymphadenopathy, hepatomegaly, and/or splenomegaly. There is high clinical variability, even within the same family (Karacan et al., 2018). [from OMIM]

Available tests

2 tests are in the database for this condition.

Clinical tests (2 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

Associated genes Help
Genes reported to contribute to the condition.

LACC1
3 tests
Also known as: C13orf31, FAMIN, JUVAR, LACC1
Summary: laccase domain containing 1

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Clinical resources

Molecular resources

Consumer resources

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