Spermatogenic failure-96 (SPGF96) is an autosomal recessive disorder characterized by male infertility due to nonobstructive azoospermia. Spermatogenesis appears to be arrested at the zygotene stage, with reduced numbers of spermatocytes and no spermatids seen in testicular tissue (Yao et al., 2022).
For a general phenotypic description and discussion of genetic heterogeneity of spermatogenic failure, see SPGF1 (258150). [from OMIM]
Also known as: NYD-SP20, NYDSP20, POF25, SPGF96, SPATA22
Summary: spermatogenesis associated 22
IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.
