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Spermatic cord cancer

MedGen UID:
102278
•Concept ID:
C0153603
•
Neoplastic Process
Synonyms: cancer of spermatic cord; Malignant Neoplasm of Spermatic Cord; malignant neoplasm of spermatic cord; Malignant Neoplasm of the Spermatic Cord; malignant neoplasm of the spermatic cord; Malignant Spermatic Cord Neoplasm; malignant spermatic cord neoplasm; Malignant Spermatic Cord Tumor; malignant spermatic cord tumor; malignant spermatic cord tumour; Malignant tumor of spermatic cord; Malignant Tumor of Spermatic Cord; malignant tumor of spermatic cord; Malignant Tumor of the Spermatic Cord; malignant tumor of the spermatic cord; malignant tumour of spermatic cord; malignant tumour of the spermatic cord; Spermatic cord Ca; spermatic cord Ca; spermatic cord cancer
SNOMED CT: Spermatic cord Ca (363453008); Malignant tumor of spermatic cord (363453008)
 
Monarch Initiative: MONDO:0001654

Definition

A primary or metastatic malignant neoplasm that affects the spermatic cord. [from NCI]

Professional guidelines

PubMed

Diagnosis and management of spermatic cord tumors.
Moschini M, Mattei A
Curr Opin Urol 2017 Jan;27(1):76-79. doi: 10.1097/MOU.0000000000000318. PMID: 27262142
Management of Truncal Sarcoma.
Mullinax JE, Gonzalez RJ
Surg Clin North Am 2016 Oct;96(5):1003-13. doi: 10.1016/j.suc.2016.06.005. PMID: 27542639
Testicular torsion and the acute scrotum: current emergency management.
Ta A, D'Arcy FT, Hoag N, D'Arcy JP, Lawrentschuk N
Eur J Emerg Med 2016 Jun;23(3):160-5. doi: 10.1097/MEJ.0000000000000303. PMID: 26267075

Recent clinical studies

Etiology

Scrotal Masses.
Langan RC, Puente MEE
Am Fam Physician 2022 Aug;106(2):184-189. PMID: 35977130
Men's Health: Scrotal and Testicular Conditions.
Rew KT, Langan RC, Hadj-Moussa M, Heidelbaugh JJ
FP Essent 2021 Apr;503:23-27. PMID: 33856180
Diagnosis and management of spermatic cord tumors.
Moschini M, Mattei A
Curr Opin Urol 2017 Jan;27(1):76-79. doi: 10.1097/MOU.0000000000000318. PMID: 27262142
Undescended Testes: A Clinical and Surgical Review.
Fantasia J, Aidlen J, Lathrop W, Ellsworth P
Urol Nurs 2015 May-Jun;35(3):117-26. PMID: 26298946
Primary spermatic cord tumors: disease characteristics, prognostic factors, and treatment outcomes.
Rodríguez D, Barrisford GW, Sanchez A, Preston MA, Kreydin EI, Olumi AF
Urol Oncol 2014 Jan;32(1):52.e19-25. Epub 2013 Nov 13 doi: 10.1016/j.urolonc.2013.08.009. PMID: 24239475

Diagnosis

Abdominal Pain in the Emergency Department: Missed Diagnoses.
Halsey-Nichols M, McCoin N
Emerg Med Clin North Am 2021 Nov;39(4):703-717. Epub 2021 Sep 9 doi: 10.1016/j.emc.2021.07.005. PMID: 34600632
Diagnosis and management of spermatic cord tumors.
Moschini M, Mattei A
Curr Opin Urol 2017 Jan;27(1):76-79. doi: 10.1097/MOU.0000000000000318. PMID: 27262142
CT of inguinal canal lipomas and fat-containing inguinal hernias.
Fataar S
J Med Imaging Radiat Oncol 2011 Oct;55(5):485-92. doi: 10.1111/j.1754-9485.2011.02288.x. PMID: 22008167
Testicular ultrasound.
Blaivas M, Brannam L
Emerg Med Clin North Am 2004 Aug;22(3):723-48, ix. doi: 10.1016/j.emc.2004.04.002. PMID: 15301848
Testicular masses.
Junnila J, Lassen P
Am Fam Physician 1998 Feb 15;57(4):685-92. PMID: 9490992

Therapy

The role of multiparametric ultrasound in the diagnosis of paediatric scrotal pathology.
Huang DY, Pesapane F, Rafailidis V, Deganello A, Sellars ME, Sidhu PS
Br J Radiol 2020 Jun;93(1110):20200063. Epub 2020 Apr 23 doi: 10.1259/bjr.20200063. PMID: 32271626Free PMC Article
Safety and efficacy of intensity-modulated radiotherapy in the management of spermatic cord sarcoma.
Cerda T, Martin É, Truc G, Créhange G, Maingon P
Cancer Radiother 2017 Feb;21(1):16-20. Epub 2016 Dec 29 doi: 10.1016/j.canrad.2016.07.102. PMID: 28041814
Spermatic cord contamination in testicular cancer.
Nazeer T, Ro JY, Kee KH, Ayala AG
Mod Pathol 1996 Jul;9(7):762-6. PMID: 8832559
Acute scrotal pathology.
Sharer WC
Surg Clin North Am 1982 Dec;62(6):955-70. doi: 10.1016/s0039-6109(16)42877-x. PMID: 6294890
Intrascrotal rhabdomyosarcoma.
Olney LE, Narayana A, Loening S, Culp DA
Urology 1979 Aug;14(2):113-25. doi: 10.1016/0090-4295(79)90142-0. PMID: 112750

Prognosis

Primary intratesticular rhabdomyosarcoma in children: a case report and review of the literature.
Yahaya JJ, Mremi A
J Med Case Rep 2021 Jan 31;15(1):37. doi: 10.1186/s13256-020-02599-z. PMID: 33516251Free PMC Article
Para-spermatic cord proximal-type epithelioid sarcoma.
Farnan J, Morrison E, Hennessey DB
BMJ Case Rep 2021 Jan 7;14(1) doi: 10.1136/bcr-2019-232385. PMID: 33414109Free PMC Article
Undescended Testes: A Clinical and Surgical Review.
Fantasia J, Aidlen J, Lathrop W, Ellsworth P
Urol Nurs 2015 May-Jun;35(3):117-26. PMID: 26298946
Primary spermatic cord tumors: disease characteristics, prognostic factors, and treatment outcomes.
Rodríguez D, Barrisford GW, Sanchez A, Preston MA, Kreydin EI, Olumi AF
Urol Oncol 2014 Jan;32(1):52.e19-25. Epub 2013 Nov 13 doi: 10.1016/j.urolonc.2013.08.009. PMID: 24239475
Paratesticular rhabdomyoma.
Kurzrock EA, Busby JE, Gandour-Edwards R
J Pediatr Surg 2003 Oct;38(10):1546-7. doi: 10.1016/s0022-3468(03)00513-x. PMID: 14577086

Clinical prediction guides

Reprint of: Updates in 2022 on the staging of testicular germ cell tumors.
Canete Portillo S, Rais-Bahrami S, Magi-Galluzzi C
Hum Pathol 2023 Mar;133:153-161. Epub 2023 Mar 8 doi: 10.1016/j.humpath.2023.02.010. PMID: 36898947
Scrotal Masses.
Langan RC, Puente MEE
Am Fam Physician 2022 Aug;106(2):184-189. PMID: 35977130
Updates in 2022 on the staging of testicular germ cell tumors.
Canete Portillo S, Rais-Bahrami S, Magi-Galluzzi C
Hum Pathol 2022 Oct;128:152-160. Epub 2022 Aug 1 doi: 10.1016/j.humpath.2022.07.009. PMID: 35926809
Safety and efficacy of intensity-modulated radiotherapy in the management of spermatic cord sarcoma.
Cerda T, Martin É, Truc G, Créhange G, Maingon P
Cancer Radiother 2017 Feb;21(1):16-20. Epub 2016 Dec 29 doi: 10.1016/j.canrad.2016.07.102. PMID: 28041814
Primary spermatic cord tumors: disease characteristics, prognostic factors, and treatment outcomes.
Rodríguez D, Barrisford GW, Sanchez A, Preston MA, Kreydin EI, Olumi AF
Urol Oncol 2014 Jan;32(1):52.e19-25. Epub 2013 Nov 13 doi: 10.1016/j.urolonc.2013.08.009. PMID: 24239475

Recent systematic reviews

Liposarcoma of spermatic cord mimicking an inguinal hernia A case report and review of the literature.
Tinozzi FP, Calì B, Bertolami M, Rebba A, Morone G, Albertario S, Abbiati F, Osman N, Ruggiero R
Ann Ital Chir 2023 Oct 10;12 PMID: 37990578
Orchidopexy for Testicular Torsion: A Systematic Review of Surgical Technique.
Moore SL, Chebbout R, Cumberbatch M, Bondad J, Forster L, Hendry J, Lamb B, MacLennan S, Nambiar A, Shah TT, Stavrinides V, Thurtle D, Pearce I, Kasivisvanathan V
Eur Urol Focus 2021 Nov;7(6):1493-1503. Epub 2020 Aug 27 doi: 10.1016/j.euf.2020.07.006. PMID: 32863201
Sertoli Cell Tumors of the Testes: Systematic Literature Review and Meta-Analysis of Outcomes in 435 Patients.
Grogg J, Schneider K, Bode PK, Kranzbühler B, Eberli D, Sulser T, Lorch A, Beyer J, Hermanns T, Fankhauser CD
Oncologist 2020 Jul;25(7):585-590. Epub 2020 Feb 11 doi: 10.1634/theoncologist.2019-0692. PMID: 32043680Free PMC Article
Near-infrared spectroscopy in the diagnosis of testicular torsion: valuable modality or waste of valuable time? A systematic review.
Laher A, Swart M, Honiball J, Perera M, Lawrentschuk N, Adam A
ANZ J Surg 2020 May;90(5):708-714. Epub 2019 Sep 11 doi: 10.1111/ans.15402. PMID: 31512384
Paratesticular seminoma: echographic features and histological diagnosis with review of the literature.
Palicelli A, Neri P, Marchioro G, De Angelis P, Bondonno G, Ramponi A
APMIS 2018 Mar;126(3):267-272. Epub 2018 Feb 7 doi: 10.1111/apm.12806. PMID: 29411910

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