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Accommodative esotropia

MedGen UID:
102331
Concept ID:
C0155336
Disease or Syndrome
Synonyms: Accommodative component in esotropia; accommodative esotropia; Esotropia with accommodative compensation
SNOMED CT: Accommodative esotropia (419494007); Accommodative component in esotropia (419494007); Esotropia with accommodative compensation (194112008)
 
HPO: HP:0020046
Monarch Initiative: MONDO:0004895

Definition

A form of esotropia (convergent deviation of the eyes) associated with activation of the accommodative reflex. [from HPO]

Term Hierarchy

Conditions with this feature

DiGeorge syndrome
MedGen UID:
4297
Concept ID:
C0012236
Disease or Syndrome
Individuals with 22q11.2 deletion syndrome (22q11.2DS) can present with a wide range of features that are highly variable, even within families. The major clinical manifestations of 22q11.2DS include congenital heart disease, particularly conotruncal malformations (ventricular septal defect, tetralogy of Fallot, interrupted aortic arch, and truncus arteriosus), palatal abnormalities (velopharyngeal incompetence, submucosal cleft palate, bifid uvula, and cleft palate), immune deficiency, characteristic facial features, and learning difficulties. Hearing loss can be sensorineural and/or conductive. Laryngotracheoesophageal, gastrointestinal, ophthalmologic, central nervous system, skeletal, and genitourinary anomalies also occur. Psychiatric illness and autoimmune disorders are more common in individuals with 22q11.2DS.
Developmental delay, language impairment, and ocular abnormalities
MedGen UID:
1824035
Concept ID:
C5774262
Disease or Syndrome
Developmental delay, language impairment, and ocular abnormalities (DEVLO) is characterized by delayed acquisition of skills particularly affecting speech and language development, although many patients show mild motor delay. Most affected individuals also have a small head circumference (down to -3 SD) and may have mild dysmorphic features. Variable ocular anomalies include strabismus, cataracts, and cortical visual impairment. Older patients require special schooling and often demonstrate behavioral abnormalities (Laboy Cintron et al., 2022).

Professional guidelines

PubMed

Eustis HS, Shah P
Am J Ophthalmol 2018 Mar;187:125-129. Epub 2018 Jan 12 doi: 10.1016/j.ajo.2018.01.005. PMID: 29339065
Gilbert AL, Koo EB, Heidary G
Semin Ophthalmol 2017;32(1):8-13. Epub 2016 Oct 11 doi: 10.1080/08820538.2016.1228398. PMID: 27726470
Wright KW
Curr Opin Ophthalmol 1994 Oct;5(5):25-9. PMID: 10150811

Recent clinical studies

Etiology

Yulek F, Yuzbasioglu S, Eyidogan D
Arq Bras Oftalmol 2021 Mar-Apr;84(2):128-132. doi: 10.5935/0004-2749.20210020. PMID: 33567009
Hutchinson AK
Eur J Ophthalmol 2012 Nov-Dec;22(6):871-7. Epub 2012 Oct 10 doi: 10.5301/ejo.5000210. PMID: 23097019
Birch EE, Wang J
Optom Vis Sci 2009 Jun;86(6):647-52. doi: 10.1097/OPX.0b013e3181a6168d. PMID: 19390468Free PMC Article
Havertape SA, Whitfill CR, Cruz OA
J Pediatr Ophthalmol Strabismus 1999 Mar-Apr;36(2):69-73. doi: 10.3928/0191-3913-19990301-05. PMID: 10204132
Baker JD, Parks MM
Am J Ophthalmol 1980 Jul;90(1):11-8. doi: 10.1016/s0002-9394(14)75070-6. PMID: 7395949

Diagnosis

Brodsky MC, Jung J
Ophthalmology 2015 Aug;122(8):1543-6. doi: 10.1016/j.ophtha.2015.03.004. PMID: 26210597
Lambert SR
Ophthalmol Clin North Am 2001 Sep;14(3):425-32. doi: 10.1016/s0896-1549(05)70240-6. PMID: 11705142
Carruthers J
Curr Opin Ophthalmol 1996 Oct;7(5):3-7. doi: 10.1097/00055735-199610000-00002. PMID: 10165105
Spiritus M
Curr Opin Ophthalmol 1994 Oct;5(5):11-6. PMID: 10150808
Nelson LB, Wagner RS, Simon JW, Harley RD
Surv Ophthalmol 1987 May-Jun;31(6):363-83. doi: 10.1016/0039-6257(87)90030-0. PMID: 3303394

Therapy

Finlay AL
Cont Lens Anterior Eye 2007 May;30(2):76-83. doi: 10.1016/j.clae.2007.02.009. PMID: 17448926
Wright KW
Curr Opin Ophthalmol 1994 Oct;5(5):25-9. PMID: 10150811
Hiatt RL
Curr Opin Ophthalmol 1991 Feb;2(1):63-8. doi: 10.1097/00055735-199102000-00009. PMID: 10149291
Nelson LB, Wagner RS, Simon JW, Harley RD
Surv Ophthalmol 1987 May-Jun;31(6):363-83. doi: 10.1016/0039-6257(87)90030-0. PMID: 3303394
Baker JD, Parks MM
Am J Ophthalmol 1980 Jul;90(1):11-8. doi: 10.1016/s0002-9394(14)75070-6. PMID: 7395949

Prognosis

Zakher M, Simon JW, Zobal-Ratner J
J Binocul Vis Ocul Motil 2019 Jan-Mar;69(1):24-25. Epub 2019 Feb 26 doi: 10.1080/2576117X.2019.1565906. PMID: 30806582
Finlay AL
Cont Lens Anterior Eye 2007 May;30(2):76-83. doi: 10.1016/j.clae.2007.02.009. PMID: 17448926
Lambert SR
Ophthalmol Clin North Am 2001 Sep;14(3):425-32. doi: 10.1016/s0896-1549(05)70240-6. PMID: 11705142
Carruthers J
Curr Opin Ophthalmol 1996 Oct;7(5):3-7. doi: 10.1097/00055735-199610000-00002. PMID: 10165105
Baker JD, Parks MM
Am J Ophthalmol 1980 Jul;90(1):11-8. doi: 10.1016/s0002-9394(14)75070-6. PMID: 7395949

Clinical prediction guides

Finlay AL
Cont Lens Anterior Eye 2007 May;30(2):76-83. doi: 10.1016/j.clae.2007.02.009. PMID: 17448926
Lowery RS, Hutchinson A, Lambert SR
Compr Ophthalmol Update 2006 May-Jun;7(3):145-9. PMID: 16882403
Carruthers J
Curr Opin Ophthalmol 1996 Oct;7(5):3-7. doi: 10.1097/00055735-199610000-00002. PMID: 10165105
Raab EL, Spierer A
Arch Ophthalmol 1986 Dec;104(12):1777-9. doi: 10.1001/archopht.1986.01050240051038. PMID: 3789977
Raab EL
J Pediatr Ophthalmol Strabismus 1985 Mar-Apr;22(2):58-9. doi: 10.3928/0191-3913-19850301-06. PMID: 3989640

Recent systematic reviews

Ferreira A, Marta A, Baptista PM, Caiado F, Abreu AC, Maia S, Miranda V, Pinto MC, Parreira R, Menéres P
Ophthalmic Res 2022;65(4):361-376. Epub 2022 Feb 28 doi: 10.1159/000523816. PMID: 35226900

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