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Abnormal nail shape

MedGen UID:
1052475
Concept ID:
CN378212
Finding
HPO: HP:0025755

Definition

An abnormality affecting the outline (shape) or contour of the nail. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal nail shape

Professional guidelines

PubMed

Mahmoud R, Leonenko A, Butler MG, Flodman P, Gold JA, Miller JL, Roof E, Dykens E, Driscoll DJ, Kimonis V
Clin Genet 2021 Jul;100(1):29-39. Epub 2021 Mar 13 doi: 10.1111/cge.13947. PMID: 33615449Free PMC Article
Sapundzhieva T, Karalilova R, Batalov A
Rheumatol Int 2020 Jun;40(6):837-848. Epub 2020 Mar 24 doi: 10.1007/s00296-020-04559-8. PMID: 32211929
Di Chiacchio N, Kadunc BV, Trindade de Almeida AR, Madeira CL
J Am Acad Dermatol 2006 Dec;55(6):1081-4. Epub 2006 Sep 6 doi: 10.1016/j.jaad.2006.05.045. PMID: 17097403

Recent clinical studies

Etiology

Kashiyama K, Nakano M, Higashi A, Ashizuka S, Moriuchi Y, Iwao A, Tanaka K
Dermatol Ther 2021 Nov;34(6):e15163. Epub 2021 Oct 25 doi: 10.1111/dth.15163. PMID: 34665925
Mrzljak A, Popić J, Ožanić Bulić S
Acta Dermatovenerol Croat 2021 Apr;291(1):56-57. PMID: 34477067
Kim JY, Park SY, Jin SP, Yoon HS, Cho S, Park HS
Dermatol Surg 2013 Oct;39(10):1520-6. doi: 10.1111/dsu.12312. PMID: 24090262
Goldfarb CA, Wustrack R, Pratt JA, Mender A, Manske PR
J Hand Surg Am 2007 Feb;32(2):157-61. doi: 10.1016/j.jhsa.2006.10.019. PMID: 17275588
Pearson HJ, Bury RN, Wapples J, Watkin DF
J Bone Joint Surg Br 1987 Nov;69(5):840-2. doi: 10.1302/0301-620X.69B5.3680356. PMID: 3680356

Diagnosis

Lazar LT, Guldberg-Møller J, Lazar BT, Mogensen M
Microvasc Res 2023 May;147:104476. Epub 2023 Jan 16 doi: 10.1016/j.mvr.2023.104476. PMID: 36657709
Inamadar AC, Palit A
Indian J Dermatol Venereol Leprol 2012 May-Jun;78(3):271-8. doi: 10.4103/0378-6323.95441. PMID: 22565426
Kim G, Shin H
Dermatol Online J 2004 Nov 30;10(3):23. PMID: 15748593
Gao XH, Li X, Zhao Y, Wang Y, Chen HD
Int J Dermatol 2001 Apr;40(4):290-1. doi: 10.1046/j.1365-4362.2001.01212-5.x. PMID: 11454091
Cohen PR
J Am Acad Dermatol 1996 Jun;34(6):943-53; quiz 954-6. doi: 10.1016/s0190-9622(96)90269-8. PMID: 8647987

Therapy

Lazar LT, Guldberg-Møller J, Lazar BT, Mogensen M
Microvasc Res 2023 May;147:104476. Epub 2023 Jan 16 doi: 10.1016/j.mvr.2023.104476. PMID: 36657709
Mahmoud R, Leonenko A, Butler MG, Flodman P, Gold JA, Miller JL, Roof E, Dykens E, Driscoll DJ, Kimonis V
Clin Genet 2021 Jul;100(1):29-39. Epub 2021 Mar 13 doi: 10.1111/cge.13947. PMID: 33615449Free PMC Article
Jain A, Stokes J, Gardiner MD, Cook JA, Jones A, Cooper C, Shirkey B, Sierakowski A, Beard D, Greig AVH, Dupré S, Adami RZ, Baker B, Fleet M, Miles D, Nicholas R, Nicola A, Plonczak A, Sleiwah A, Williams G; NINJA Collaborative; NINJA Collaborative
J Plast Reconstr Aesthet Surg 2021 Jan;74(1):94-100. Epub 2020 Aug 5 doi: 10.1016/j.bjps.2020.08.002. PMID: 32917568
Dikmen A, Ozer K, Ulusoy MG, Gursoy K, Koçer U
Dermatol Surg 2017 Dec;43(12):1474-1482. doi: 10.1097/DSS.0000000000001252. PMID: 28857941
Piraccini BM, Parente GL, Varotti E, Tosti A
Pediatr Dermatol 2000 Sep-Oct;17(5):348-51. doi: 10.1046/j.1525-1470.2000.017005348.x. PMID: 11085659

Prognosis

Bergendal B, Norderyd J, Zhou X, Klar J, Dahl N
BMC Med Genet 2016 Nov 24;17(1):88. doi: 10.1186/s12881-016-0349-4. PMID: 27881089Free PMC Article
Kantaputra P, Kaewgahya M, Jotikasthira D, Kantaputra W
Am J Med Genet A 2014 Apr;164A(4):1041-8. Epub 2014 Jan 23 doi: 10.1002/ajmg.a.36388. PMID: 24458874
Fuchsbauer M, Ozdemir C, Scharffetter-Kochanek K
J Cosmet Dermatol 2007 Mar;6(1):27-30. doi: 10.1111/j.1473-2165.2007.00263.x. PMID: 17348992
Lim TW, Paik JH, Kim NI
J Dermatol 1999 Oct;26(10):677-81. doi: 10.1111/j.1346-8138.1999.tb02071.x. PMID: 10554435
Dumontier C, Gilbert A, Tubiana R
J Hand Surg Br 1995 Dec;20(6):830-5. doi: 10.1016/s0266-7681(95)80057-3. PMID: 8770751

Clinical prediction guides

Jain A, Stokes J, Gardiner MD, Cook JA, Jones A, Cooper C, Shirkey B, Sierakowski A, Beard D, Greig AVH, Dupré S, Adami RZ, Baker B, Fleet M, Miles D, Nicholas R, Nicola A, Plonczak A, Sleiwah A, Williams G; NINJA Collaborative; NINJA Collaborative
J Plast Reconstr Aesthet Surg 2021 Jan;74(1):94-100. Epub 2020 Aug 5 doi: 10.1016/j.bjps.2020.08.002. PMID: 32917568
Kantaputra P, Kaewgahya M, Jotikasthira D, Kantaputra W
Am J Med Genet A 2014 Apr;164A(4):1041-8. Epub 2014 Jan 23 doi: 10.1002/ajmg.a.36388. PMID: 24458874
Kim JY
J Am Podiatr Med Assoc 2012 May-Jun;102(3):198-204. doi: 10.7547/1020198. PMID: 22659762
Perrin C, Baran R, Balaguer T, Chignon-Sicard B, Cannata GE, Petrella T, Michiels JF
Am J Dermatopathol 2010 Feb;32(1):1-8. doi: 10.1097/DAD.0b013e3181af8516. PMID: 20098079
Herzberg AJ
Clin Podiatr Med Surg 1995 Apr;12(2):309-18. PMID: 7600505

Recent systematic reviews

Lazar LT, Guldberg-Møller J, Lazar BT, Mogensen M
Microvasc Res 2023 May;147:104476. Epub 2023 Jan 16 doi: 10.1016/j.mvr.2023.104476. PMID: 36657709
Sapundzhieva T, Karalilova R, Batalov A
Rheumatol Int 2020 Jun;40(6):837-848. Epub 2020 Mar 24 doi: 10.1007/s00296-020-04559-8. PMID: 32211929

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