U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Bone marrow granuloma

MedGen UID:
1053460
•Concept ID:
CN376667
•
Finding
HPO: HP:6000154

Definition

A granuloma (a focal aggregate of immune cells that forms in response to a persistent inflammatory stimulus) localiyed to the bone marrow. A granuloma characteristically demonstrates the compact organization of mature macrophages, which may or may not be associated with other inflammatory cell types. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBone marrow granuloma

Professional guidelines

PubMed

Haematological profiles after Intensive phase of Anti Koch Treatment with special emphasis on bone marrow changes.
Basu D, Biswas S, Ray R
Indian J Tuberc 2021 Apr;68(2):201-204. Epub 2020 Aug 12 doi: 10.1016/j.ijtb.2020.08.006. PMID: 33845952

Recent clinical studies

Etiology

Hidden tuberculosis revealed by bone marrow biopsy as cause of fever of unknown origin.
Roelandt PR, Dendooven M, De Groef K, Van Couter A
Acta Clin Belg 2006 Nov-Dec;61(6):363-6. doi: 10.1179/acb.2006.058. PMID: 17323848

Diagnosis

Bone marrow granuloma in a child with pyrexia of unknown origin: A clue for diagnosis of brucellosis.
Suthar R, Bansal D, Suri D, Sharma P, Ray P
Indian J Pathol Microbiol 2019 Jul-Sep;62(3):493-494. doi: 10.4103/IJPM.IJPM_7_18. PMID: 31361252
Fever of unknown origin and isolated noncaseating granuloma of the marrow: could this be sarcoidosis?
Miller AC, Chacko T, Rashid RM, Ledford DK
Allergy Asthma Proc 2007 Mar-Apr;28(2):230-5. doi: 10.2500/aap.2007.28.2982. PMID: 17479610
Disseminated Mycobacterium kansasii infection in an HIV-negative patient presenting with mimicking multiple bone metastases.
Tsai CW, Wang JT, Tsai CC, Yeh KH
Diagn Microbiol Infect Dis 2006 Mar;54(3):211-6. Epub 2006 Jan 19 doi: 10.1016/j.diagmicrobio.2005.09.010. PMID: 16423487
Differential diagnoses of bone marrow granuloma.
Eid A, Carion W, Nystrom JS
West J Med 1996 Jun;164(6):510-5. PMID: 8764626Free PMC Article

Therapy

Haematological profiles after Intensive phase of Anti Koch Treatment with special emphasis on bone marrow changes.
Basu D, Biswas S, Ray R
Indian J Tuberc 2021 Apr;68(2):201-204. Epub 2020 Aug 12 doi: 10.1016/j.ijtb.2020.08.006. PMID: 33845952
Fever of unknown origin and isolated noncaseating granuloma of the marrow: could this be sarcoidosis?
Miller AC, Chacko T, Rashid RM, Ledford DK
Allergy Asthma Proc 2007 Mar-Apr;28(2):230-5. doi: 10.2500/aap.2007.28.2982. PMID: 17479610
Amiodarone-associated granuloma in bone marrow.
Rosenbaum H, Ben-Arie Y, Azzam ZS, Krivoy N
Ann Pharmacother 1998 Jan;32(1):60-2. doi: 10.1345/aph.17061. PMID: 9475823
Differential diagnoses of bone marrow granuloma.
Eid A, Carion W, Nystrom JS
West J Med 1996 Jun;164(6):510-5. PMID: 8764626Free PMC Article

Prognosis

Haematological profiles after Intensive phase of Anti Koch Treatment with special emphasis on bone marrow changes.
Basu D, Biswas S, Ray R
Indian J Tuberc 2021 Apr;68(2):201-204. Epub 2020 Aug 12 doi: 10.1016/j.ijtb.2020.08.006. PMID: 33845952
Granulomatous bone marrow disease. A review of the literature and clinicopathologic analysis of 58 cases.
Bodem CR, Hamory BH, Taylor HM, Kleopfer L
Medicine (Baltimore) 1983 Nov;62(6):372-83. PMID: 6314087

Clinical prediction guides

Haematological profiles after Intensive phase of Anti Koch Treatment with special emphasis on bone marrow changes.
Basu D, Biswas S, Ray R
Indian J Tuberc 2021 Apr;68(2):201-204. Epub 2020 Aug 12 doi: 10.1016/j.ijtb.2020.08.006. PMID: 33845952

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...