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Mitral opening snap

MedGen UID:
1054425
•Concept ID:
CN377514
•
Finding
HPO: HP:6000685

Definition

Opening snap is an additional sound heard in the diastole that is related to the opening of a stenotic but mobile mitral valve. It is described as an early diastolic, high-pitched sound, which is associated with opening of the mitral and/or tricuspid valve. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMitral opening snap

Professional guidelines

PubMed

Percutaneous balloon mitral valvuloplasty by the Inoue balloon technique: the procedure of choice for treatment of mitral stenosis.
Cheng TO, Holmes DR Jr
Am J Cardiol 1998 Mar 1;81(5):624-8. doi: 10.1016/s0002-9149(97)00978-8. PMID: 9514461

Recent clinical studies

Etiology

Late results following closed mitral valvotomy in isolated mitral valve stenosis: analysis of thirty-five years of follow-up in 240 patients using Cox regression.
Ravkilde JL, Hansen PS
Thorac Cardiovasc Surg 1991 Jun;39(3):133-9. doi: 10.1055/s-2007-1013949. PMID: 1715614
Opening snap and isovolumic relaxation period in relation to mitral valve flow in patients with mitral stenosis. Significance of A2--OS interval.
Kalmanson D, Veyrat C, Bernier A, Witchitz S, Chiche P
Br Heart J 1976 Feb;38(2):135-46. doi: 10.1136/hrt.38.2.135. PMID: 1259828Free PMC Article

Diagnosis

Mitral stenosis: mitral dome excursion at M1 and the mitral opening snap--the concept of reciprocal heart sounds.
Barrington WW, Boudoulas H, Bashore T, Olson S, Wooley CF
Am Heart J 1988 Jun;115(6):1280-90. doi: 10.1016/0002-8703(88)90022-1. PMID: 3376846
Nonobstructive hypertrophic cardiomyopathy mimicking mitral stenosis. Documentation by echocardiography, phonocardiography and intracardiac pressure and sound recordings.
Smith MR, Agruss NS, Levenson NI, Adolph RJ
Am J Cardiol 1975 Jan;35(1):89-96. doi: 10.1016/0002-9149(75)90564-0. PMID: 122786
The second sound-mitral opening snap (A2-OS) interval during exercise in the evaluation of mitral stenosis.
Delman AJ, Gordon GM, Stein E, Escher DJ
Circulation 1966 Mar;33(3):399-403. doi: 10.1161/01.cir.33.3.399. PMID: 5904417
The mitral opening snap in the quantitative diagnosis of mitral stenosis.
BAYER O, LOOGEN F, WOLTER HH
Am Heart J 1956 Feb;51(2):234-45. doi: 10.1016/0002-8703(56)90084-9. PMID: 13282841

Prognosis

Late results following closed mitral valvotomy in isolated mitral valve stenosis: analysis of thirty-five years of follow-up in 240 patients using Cox regression.
Ravkilde JL, Hansen PS
Thorac Cardiovasc Surg 1991 Jun;39(3):133-9. doi: 10.1055/s-2007-1013949. PMID: 1715614

Clinical prediction guides

Late results following closed mitral valvotomy in isolated mitral valve stenosis: analysis of thirty-five years of follow-up in 240 patients using Cox regression.
Ravkilde JL, Hansen PS
Thorac Cardiovasc Surg 1991 Jun;39(3):133-9. doi: 10.1055/s-2007-1013949. PMID: 1715614
Mitral stenosis: mitral dome excursion at M1 and the mitral opening snap--the concept of reciprocal heart sounds.
Barrington WW, Boudoulas H, Bashore T, Olson S, Wooley CF
Am Heart J 1988 Jun;115(6):1280-90. doi: 10.1016/0002-8703(88)90022-1. PMID: 3376846

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