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Malignant superior sulcus neoplasm

MedGen UID:
107810
•Concept ID:
C0549471
•
Neoplastic Process
Synonyms: Pancoast Tumor; Tumor, Pancoast
SNOMED CT: Superior sulcus tumor (254638002); Pancoast tumor (254638002)
 
Monarch Initiative: MONDO:0006883

Definition

A malignant neoplasm originating from the apical lung. Most malignant superior sulcus neoplasms are bronchogenic carcinomas. This tumor may be associated with Pancoast syndrome. It is also known as Pancoast tumor. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant superior sulcus neoplasm

Professional guidelines

PubMed

Management of Lung Cancer Invading the Superior Sulcus.
Kratz JR, Woodard G, Jablons DM
Thorac Surg Clin 2017 May;27(2):149-157. doi: 10.1016/j.thorsurg.2017.01.008. PMID: 28363369
Cubital tunnel syndrome - a review and management guidelines.
Assmus H, Antoniadis G, Bischoff C, Hoffmann R, Martini AK, Preissler P, Scheglmann K, Schwerdtfeger K, Wessels KD, Wüstner-Hofmann M
Cent Eur Neurosurg 2011 May;72(2):90-8. Epub 2011 May 4 doi: 10.1055/s-0031-1271800. PMID: 21547883
Treatment of superior sulcus non-small cell lung cancer.
Millward M
Asia Pac J Clin Oncol 2010 Mar;6(1):1-2. doi: 10.1111/j.1743-7563.2010.01280.x. PMID: 20398031

Recent clinical studies

Etiology

Pancoast tumor: a modern perspective on an old problem.
Glassman LR, Hyman K
Curr Opin Pulm Med 2013 Jul;19(4):340-3. doi: 10.1097/MCP.0b013e3283621b31. PMID: 23702478
Cubital tunnel syndrome - a review and management guidelines.
Assmus H, Antoniadis G, Bischoff C, Hoffmann R, Martini AK, Preissler P, Scheglmann K, Schwerdtfeger K, Wessels KD, Wüstner-Hofmann M
Cent Eur Neurosurg 2011 May;72(2):90-8. Epub 2011 May 4 doi: 10.1055/s-0031-1271800. PMID: 21547883
Resection of superior sulcus carcinomas (anterior approach).
Macchiarini P
Thorac Surg Clin 2004 May;14(2):229-40. doi: 10.1016/S1547-4127(04)00008-8. PMID: 15382299
Resection of superior sulcus tumors (posterior approach).
Kent MS, Bilsky MH, Rusch VW
Thorac Surg Clin 2004 May;14(2):217-28. doi: 10.1016/S1547-4127(04)00013-1. PMID: 15382298
Carcinoma in the superior pulmonary sulcus.
Paulson DL
Ann Thorac Surg 1979 Jul;28(1):3-4. doi: 10.1016/s0003-4975(10)63381-4. PMID: 454041

Diagnosis

Pancoast tumour: current therapeutic options.
Palumbo VD, Fazzotta S, Fatica F, D'Orazio B, Caronia FP, Cajozzo M, Damiano G, Maffongelli A, Cudia BM, Messina M, Lo Monte AI
Clin Ter 2019 Jul-Aug;170(4):e291-e294. doi: 10.7417/CT.2019.2150. PMID: 31304518
Management of Lung Cancer Invading the Superior Sulcus.
Kratz JR, Woodard G, Jablons DM
Thorac Surg Clin 2017 May;27(2):149-157. doi: 10.1016/j.thorsurg.2017.01.008. PMID: 28363369
Diagnosing and treating pancoast tumors.
Zarogoulidis K, Porpodis K, Domvri K, Eleftheriadou E, Ioannidou D, Zarogoulidis P
Expert Rev Respir Med 2016 Dec;10(12):1255-1258. Epub 2016 Oct 27 doi: 10.1080/17476348.2017.1246964. PMID: 27786592
Cubital tunnel syndrome - a review and management guidelines.
Assmus H, Antoniadis G, Bischoff C, Hoffmann R, Martini AK, Preissler P, Scheglmann K, Schwerdtfeger K, Wessels KD, Wüstner-Hofmann M
Cent Eur Neurosurg 2011 May;72(2):90-8. Epub 2011 May 4 doi: 10.1055/s-0031-1271800. PMID: 21547883
Superior sulcus tumors.
Wright CD, Mathisen DJ
Curr Treat Options Oncol 2001 Feb;2(1):43-9. doi: 10.1007/s11864-001-0015-7. PMID: 12057139

Therapy

POINT: Is N2 Disease a Contraindication for Surgical Resection for Superior Sulcus Tumors? Yes.
Tanner NT, Silvestri GA
Chest 2015 Dec;148(6):1373-1375. doi: 10.1378/chest.15-1194. PMID: 26110373
Pancoast tumor: a modern perspective on an old problem.
Glassman LR, Hyman K
Curr Opin Pulm Med 2013 Jul;19(4):340-3. doi: 10.1097/MCP.0b013e3283621b31. PMID: 23702478
Cubital tunnel syndrome - a review and management guidelines.
Assmus H, Antoniadis G, Bischoff C, Hoffmann R, Martini AK, Preissler P, Scheglmann K, Schwerdtfeger K, Wessels KD, Wüstner-Hofmann M
Cent Eur Neurosurg 2011 May;72(2):90-8. Epub 2011 May 4 doi: 10.1055/s-0031-1271800. PMID: 21547883
Superior sulcus tumors.
Wright CD, Mathisen DJ
Curr Treat Options Oncol 2001 Feb;2(1):43-9. doi: 10.1007/s11864-001-0015-7. PMID: 12057139
Pancoast tumors.
Vallières E, Karmy-Jones R, Mulligan MS, Wood DE
Curr Probl Surg 2001 May;38(5):293-376. doi: 10.1067/msg.2001.113528. PMID: 11332249

Prognosis

Harlequin sign in Pancoast tumor.
Kumar R, Bhandari S, Kloecker GH
Curr Probl Cancer 2020 Apr;44(2):100506. Epub 2019 Nov 1 doi: 10.1016/j.currproblcancer.2019.100506. PMID: 31732238
Cubital tunnel syndrome - a review and management guidelines.
Assmus H, Antoniadis G, Bischoff C, Hoffmann R, Martini AK, Preissler P, Scheglmann K, Schwerdtfeger K, Wessels KD, Wüstner-Hofmann M
Cent Eur Neurosurg 2011 May;72(2):90-8. Epub 2011 May 4 doi: 10.1055/s-0031-1271800. PMID: 21547883
Management of Pancoast tumours.
Rusch VW
Lancet Oncol 2006 Dec;7(12):997-1005. doi: 10.1016/S1470-2045(06)70974-3. PMID: 17138221
Pancoast tumors.
Vallières E, Karmy-Jones R, Mulligan MS, Wood DE
Curr Probl Surg 2001 May;38(5):293-376. doi: 10.1067/msg.2001.113528. PMID: 11332249
Superior pulmonary sulcus tumors and Pancoast's syndrome.
Arcasoy SM, Jett JR
N Engl J Med 1997 Nov 6;337(19):1370-6. doi: 10.1056/NEJM199711063371907. PMID: 9358132

Clinical prediction guides

Horner's syndrome and epidural anesthesia in labor and cesarean section.
Vogiatzaki T, Tsikouras P, Tsoleridis T, Bachar M, Christofis C, Liberis A, Galazios G
Clin Exp Obstet Gynecol 2017;44(3):337-340. PMID: 29949268
Surgical Treatment of Superior Sulcus Tumors: A 15-Year Single-center Experience.
Solli P, Casiraghi M, Brambilla D, Maisonneuve P, Spaggiari L
Semin Thorac Cardiovasc Surg 2017 Spring;29(1):79-88. Epub 2017 Feb 22 doi: 10.1053/j.semtcvs.2017.01.010. PMID: 28684003
Hybrid video-assisted and limited open (VALO) resection of superior sulcus tumors.
Nun AB, Simansky D, Rokah M, Zeitlin N, Avi RB, Soudack M, Golan N, Apel S, Bar J, Yelin A
Surg Today 2016 Jun;46(6):686-90. Epub 2015 Jul 22 doi: 10.1007/s00595-015-1225-0. PMID: 26198898
Eponyms in cardiothoracic radiology: Part I. Neoplasms.
Mohammed TL, Saettele MR, Saettele T, Patel V, Kanne JP
Curr Probl Diagn Radiol 2014 Mar-Apr;43(2):91-8. doi: 10.1067/j.cpradiol.2013.12.003. PMID: 24629662
Superior sulcus tumors.
Beyer DC, Weisenburger T
Am J Clin Oncol 1986 Apr;9(2):156-61. doi: 10.1097/00000421-198604000-00011. PMID: 3087154

Recent systematic reviews

Management of locally advanced pancoast (superior sulcus) tumors with spine involvement.
Setzer M, Robinson LA, Vrionis FD
Cancer Control 2014 Apr;21(2):158-67. doi: 10.1177/107327481402100209. PMID: 24667403

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