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Carcinoid Tumor of Uncertain Malignant Potential

MedGen UID:: 109014
•Concept ID:: C0600176
•: Neoplastic Process

Synonyms:

Argentaffinoma; Argentaffinomas

Definition

A carcinoid tumor that shows atypical characteristics and has borderline malignant potential. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVCarcinoid Tumor of Uncertain Malignant Potential

Pathological process
- Disease
  - Neoplasm
    - Neoplasm by Special Category
      - Neoplasm by Obsolete Classification
        Epithelial Neoplasm (Antiquated)
        Carcinoid Tumor of Uncertain Malignant Potential

Professional guidelines

PubMed

Carcinoid Heart Disease: Pathophysiology, Pathology, Clinical Manifestations, and Management.

Jin C, Sharma AN, Thevakumar B, Majid M, Al Chalaby S, Takahashi N, Tanious A, Arockiam AD, Beri N, Amsterdam EA
Cardiology 2021;146(1):65-73. Epub 2020 Oct 16 doi: 10.1159/000507847. PMID: 33070143

Updates and management algorithm for neuroendocrine tumors of the uterine cervix.

Salvo G, Gonzalez Martin A, Gonzales NR, Frumovitz M
Int J Gynecol Cancer 2019 Jul;29(6):986-995. doi: 10.1136/ijgc-2019-000504. PMID: 31263021

Pulmonary neuroendocrine (carcinoid) tumors: European Neuroendocrine Tumor Society expert consensus and recommendations for best practice for typical and atypical pulmonary carcinoids.

Caplin ME, Baudin E, Ferolla P, Filosso P, Garcia-Yuste M, Lim E, Oberg K, Pelosi G, Perren A, Rossi RE, Travis WD; ENETS consensus conference participants
Ann Oncol 2015 Aug;26(8):1604-20. Epub 2015 Feb 2 doi: 10.1093/annonc/mdv041. PMID: 25646366

See all (588)

Recent clinical studies

Etiology

Pulmonary Neuroendocrine Tumors.

Borczuk AC
Surg Pathol Clin 2020 Mar;13(1):35-55. Epub 2019 Nov 29 doi: 10.1016/j.path.2019.10.002. PMID: 32005434

The Problem of Appendiceal Carcinoids.

Galanopoulos M, Toumpanakis C
Endocrinol Metab Clin North Am 2018 Sep;47(3):661-669. Epub 2018 Jul 13 doi: 10.1016/j.ecl.2018.04.004. PMID: 30098722

Bronchial and Thymic Carcinoid Tumors.

Litvak A, Pietanza MC
Hematol Oncol Clin North Am 2016 Feb;30(1):83-102. doi: 10.1016/j.hoc.2015.09.003. PMID: 26614370

Carcinoid and neuroendocrine tumors: building on success.

Kunz PL
J Clin Oncol 2015 Jun 1;33(16):1855-63. Epub 2015 Apr 27 doi: 10.1200/JCO.2014.60.2532. PMID: 25918282

Neuroendocrine tumours.

Barakat MT, Meeran K, Bloom SR
Endocr Relat Cancer 2004 Mar;11(1):1-18. doi: 10.1677/erc.0.0110001. PMID: 15027882

See all (2823)

Diagnosis

Pulmonary Neuroendocrine Tumors.

Borczuk AC
Surg Pathol Clin 2020 Mar;13(1):35-55. Epub 2019 Nov 29 doi: 10.1016/j.path.2019.10.002. PMID: 32005434

Carcinoid-syndrome: recent advances, current status and controversies.

Ito T, Lee L, Jensen RT
Curr Opin Endocrinol Diabetes Obes 2018 Feb;25(1):22-35. doi: 10.1097/MED.0000000000000376. PMID: 29120923 Free PMC Article

Carcinoid tumors.

Robertson RG, Geiger WJ, Davis NB
Am Fam Physician 2006 Aug 1;74(3):429-34. PMID: 16913162

Rectal carcinoids.

Wang AY, Ahmad NA
Curr Opin Gastroenterol 2006 Sep;22(5):529-35. doi: 10.1097/01.mog.0000239868.27328.1d. PMID: 16891885

Carcinoid tumour.

Caplin ME, Buscombe JR, Hilson AJ, Jones AL, Watkinson AF, Burroughs AK
Lancet 1998 Sep 5;352(9130):799-805. doi: 10.1016/S0140-6736(98)02286-7. PMID: 9737302

See all (5184)

Therapy

Carcinoid-syndrome: recent advances, current status and controversies.

Ito T, Lee L, Jensen RT
Curr Opin Endocrinol Diabetes Obes 2018 Feb;25(1):22-35. doi: 10.1097/MED.0000000000000376. PMID: 29120923 Free PMC Article

Bronchial and Thymic Carcinoid Tumors.

Litvak A, Pietanza MC
Hematol Oncol Clin North Am 2016 Feb;30(1):83-102. doi: 10.1016/j.hoc.2015.09.003. PMID: 26614370

Gastric carcinoid.

Mulkeen A, Cha C
Curr Opin Oncol 2005 Jan;17(1):1-6. doi: 10.1097/01.cco.0000147899.04701.c6. PMID: 15608504

Carcinoid tumor.

Kinova S, Duris I
Bratisl Lek Listy 2001;102(11):495-504. PMID: 11901706

Carcinoid tumours.

Janmohamed S, Bloom SR
Postgrad Med J 1997 Apr;73(858):207-14. doi: 10.1136/pgmj.73.858.207. PMID: 9156122 Free PMC Article

See all (1904)

Prognosis

Characterization, Prognosis, and Treatment of Patients With Metastatic Lung Carcinoid Tumors.

Robelin P, Hadoux J, Forestier J, Planchard D, Hervieu V, Berdelou A, Scoazec JY, Valette PJ, Leboulleux S, Ducreux M, Lombard-Bohas C, Baudin E, Walter T
J Thorac Oncol 2019 Jun;14(6):993-1002. Epub 2019 Feb 13 doi: 10.1016/j.jtho.2019.02.002. PMID: 30771520

Carcinoid tumors.

Pinchot SN, Holen K, Sippel RS, Chen H
Oncologist 2008 Dec;13(12):1255-69. Epub 2008 Dec 17 doi: 10.1634/theoncologist.2008-0207. PMID: 19091780 Free PMC Article

One hundred years after "carcinoid": epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United States.

Yao JC, Hassan M, Phan A, Dagohoy C, Leary C, Mares JE, Abdalla EK, Fleming JB, Vauthey JN, Rashid A, Evans DB
J Clin Oncol 2008 Jun 20;26(18):3063-72. doi: 10.1200/JCO.2007.15.4377. PMID: 18565894

Rectal carcinoids.

Wang AY, Ahmad NA
Curr Opin Gastroenterol 2006 Sep;22(5):529-35. doi: 10.1097/01.mog.0000239868.27328.1d. PMID: 16891885

Carcinoid tumours.

Tiensuu Janson EM, Oberg KE
Baillieres Clin Gastroenterol 1996 Dec;10(4):589-601. doi: 10.1016/s0950-3528(96)90015-9. PMID: 9113314

See all (3019)

Clinical prediction guides

Cardiac Imaging in Carcinoid Heart Disease.

Baron T, Bergsten J, Albåge A, Lundin L, Sörensen J, Öberg K, Flachskampf FA
JACC Cardiovasc Imaging 2021 Nov;14(11):2240-2253. Epub 2021 Apr 14 doi: 10.1016/j.jcmg.2020.12.030. PMID: 33865761

Appendix Tumor Microenvironment.

Roncati L, Gasparri P, Gallo G, Bernardelli G, Zanelli G, Manenti A
Adv Exp Med Biol 2020;1226:87-95. doi: 10.1007/978-3-030-36214-0_7. PMID: 32030678

Characterization, Prognosis, and Treatment of Patients With Metastatic Lung Carcinoid Tumors.

Carcinoid and neuroendocrine tumors: building on success.

Kunz PL
J Clin Oncol 2015 Jun 1;33(16):1855-63. Epub 2015 Apr 27 doi: 10.1200/JCO.2014.60.2532. PMID: 25918282

Rectal carcinoids.

Wang AY, Ahmad NA
Curr Opin Gastroenterol 2006 Sep;22(5):529-35. doi: 10.1097/01.mog.0000239868.27328.1d. PMID: 16891885

See all (1867)

Recent systematic reviews

A Systematic Review of Economic and Quality-of-Life Research in Carcinoid Syndrome.

Pan IW, Halperin DM, Kim B, Yao JC, Shih YT
Pharmacoeconomics 2021 Nov;39(11):1271-1297. Epub 2021 Aug 11 doi: 10.1007/s40273-021-01071-0. PMID: 34378163 Free PMC Article

Management and outcome of middle ear adenomatous neuroendocrine tumours: A systematic review.

Engel MSD, van der Lans RJL, Jansen JC, Leemans CR, Bloemena E, Lissenberg-Witte BI, Rijken JA, Smit CF, Hensen EF
Oral Oncol 2021 Oct;121:105465. Epub 2021 Aug 2 doi: 10.1016/j.oraloncology.2021.105465. PMID: 34352556

Endometriosis and its correlation with carcinoid tumor of the appendix: a systematic review.

Villaescusa M, Andres MP, Amaral AC, Barbosa RN, Abrão MS
Minerva Obstet Gynecol 2021 Oct;73(5):606-613. Epub 2021 Apr 27 doi: 10.23736/S2724-606X.21.04792-4. PMID: 33904692

Pulmonary neuroendocrine (carcinoid) tumors: European Neuroendocrine Tumor Society expert consensus and recommendations for best practice for typical and atypical pulmonary carcinoids.

Ectopic ACTH syndrome.

Isidori AM, Lenzi A
Arq Bras Endocrinol Metabol 2007 Nov;51(8):1217-25. doi: 10.1590/s0004-27302007000800007. PMID: 18209859

See all (45)

MedGen

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Carcinoid Tumor of Uncertain Malignant Potential

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Recent activity