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Acute bronchiolitis

MedGen UID:
113
•Concept ID:
C0001311
•
Disease or Syndrome
Synonyms: Acute Bronchiolitis; acute bronchiolitis; acute Bronchiolitis; Acute capillary bronchiolitis; acute capillary bronchiolitis; Capillary pneumonia; capillary pneumonia
SNOMED CT: Acute bronchiolitis (5505005); Capillary pneumonia (5505005); Acute capillary bronchiolitis (5505005)
 
Monarch Initiative: MONDO:0020680

Definition

Acute inflammation of the bronchioles usually caused by the respiratory syncytial virus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcute bronchiolitis

Professional guidelines

PubMed

Expert consensus on the diagnosis, treatment, and prevention of respiratory syncytial virus infections in children.
Zhang XL, Zhang X, Hua W, Xie ZD, Liu HM, Zhang HL, Chen BQ, Chen Y, Sun X, Xu Y, Shu SN, Zhao SY, Shang YX, Cao L, Jia YH, Lin LN, Li J, Hao CL, Dong XY, Lin DJ, Xu HM, Zhao DY, Zeng M, Chen ZM, Huang LS
World J Pediatr 2024 Jan;20(1):11-25. Epub 2023 Dec 8 doi: 10.1007/s12519-023-00777-9. PMID: 38064012Free PMC Article
UPDATE - 2022 Italian guidelines on the management of bronchiolitis in infants.
Manti S, Staiano A, Orfeo L, Midulla F, Marseglia GL, Ghizzi C, Zampogna S, Carnielli VP, Favilli S, Ruggieri M, Perri D, Di Mauro G, Gattinara GC, D'Avino A, Becherucci P, Prete A, Zampino G, Lanari M, Biban P, Manzoni P, Esposito S, Corsello G, Baraldi E
Ital J Pediatr 2023 Feb 10;49(1):19. doi: 10.1186/s13052-022-01392-6. PMID: 36765418Free PMC Article
Acute bronchiolitis: assessment and management in the emergency department.
Joseph MM, Edwards A
Pediatr Emerg Med Pract 2019 Oct;16(10):1-24. Epub 2019 Oct 2 PMID: 31557431

Curated

UK NICE Guideline NG9, Bronchiolitis in children: diagnosis and management, 2021

Recent clinical studies

Etiology

Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old.
Roqué-Figuls M, Giné-Garriga M, Granados Rugeles C, Perrotta C, Vilaró J
Cochrane Database Syst Rev 2023 Apr 3;4(4):CD004873. doi: 10.1002/14651858.CD004873.pub6. PMID: 37010196Free PMC Article
UPDATE - 2022 Italian guidelines on the management of bronchiolitis in infants.
Manti S, Staiano A, Orfeo L, Midulla F, Marseglia GL, Ghizzi C, Zampogna S, Carnielli VP, Favilli S, Ruggieri M, Perri D, Di Mauro G, Gattinara GC, D'Avino A, Becherucci P, Prete A, Zampino G, Lanari M, Biban P, Manzoni P, Esposito S, Corsello G, Baraldi E
Ital J Pediatr 2023 Feb 10;49(1):19. doi: 10.1186/s13052-022-01392-6. PMID: 36765418Free PMC Article
Respiratory Syncytial Virus is the Most Common Causative Agent of Viral Bronchiolitis in Young Children: An Updated Review.
Hon KL, Leung AKC, Wong AHC, Dudi A, Leung KKY
Curr Pediatr Rev 2023;19(2):139-149. doi: 10.2174/1573396318666220810161945. PMID: 35950255
Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old.
Roqué i Figuls M, Giné-Garriga M, Granados Rugeles C, Perrotta C, Vilaró J
Cochrane Database Syst Rev 2016 Feb 1;2(2):CD004873. doi: 10.1002/14651858.CD004873.pub5. PMID: 26833493Free PMC Article
Acute bronchiolitis.
Teshome G, Gattu R, Brown R
Pediatr Clin North Am 2013 Oct;60(5):1019-34. Epub 2013 Jul 24 doi: 10.1016/j.pcl.2013.06.005. PMID: 24093893

Diagnosis

UPDATE - 2022 Italian guidelines on the management of bronchiolitis in infants.
Manti S, Staiano A, Orfeo L, Midulla F, Marseglia GL, Ghizzi C, Zampogna S, Carnielli VP, Favilli S, Ruggieri M, Perri D, Di Mauro G, Gattinara GC, D'Avino A, Becherucci P, Prete A, Zampino G, Lanari M, Biban P, Manzoni P, Esposito S, Corsello G, Baraldi E
Ital J Pediatr 2023 Feb 10;49(1):19. doi: 10.1186/s13052-022-01392-6. PMID: 36765418Free PMC Article
Respiratory Syncytial Virus is the Most Common Causative Agent of Viral Bronchiolitis in Young Children: An Updated Review.
Hon KL, Leung AKC, Wong AHC, Dudi A, Leung KKY
Curr Pediatr Rev 2023;19(2):139-149. doi: 10.2174/1573396318666220810161945. PMID: 35950255
Acute bronchiolitis: assessment and management in the emergency department.
Joseph MM, Edwards A
Pediatr Emerg Med Pract 2019 Oct;16(10):1-24. Epub 2019 Oct 2 PMID: 31557431
Acute bronchiolitis.
Teshome G, Gattu R, Brown R
Pediatr Clin North Am 2013 Oct;60(5):1019-34. Epub 2013 Jul 24 doi: 10.1016/j.pcl.2013.06.005. PMID: 24093893
Respiratory syncytial virus--a comprehensive review.
Borchers AT, Chang C, Gershwin ME, Gershwin LJ
Clin Rev Allergy Immunol 2013 Dec;45(3):331-79. doi: 10.1007/s12016-013-8368-9. PMID: 23575961Free PMC Article

Therapy

Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old.
Roqué-Figuls M, Giné-Garriga M, Granados Rugeles C, Perrotta C, Vilaró J
Cochrane Database Syst Rev 2023 Apr 3;4(4):CD004873. doi: 10.1002/14651858.CD004873.pub6. PMID: 37010196Free PMC Article
UPDATE - 2022 Italian guidelines on the management of bronchiolitis in infants.
Manti S, Staiano A, Orfeo L, Midulla F, Marseglia GL, Ghizzi C, Zampogna S, Carnielli VP, Favilli S, Ruggieri M, Perri D, Di Mauro G, Gattinara GC, D'Avino A, Becherucci P, Prete A, Zampino G, Lanari M, Biban P, Manzoni P, Esposito S, Corsello G, Baraldi E
Ital J Pediatr 2023 Feb 10;49(1):19. doi: 10.1186/s13052-022-01392-6. PMID: 36765418Free PMC Article
Respiratory Syncytial Virus is the Most Common Causative Agent of Viral Bronchiolitis in Young Children: An Updated Review.
Hon KL, Leung AKC, Wong AHC, Dudi A, Leung KKY
Curr Pediatr Rev 2023;19(2):139-149. doi: 10.2174/1573396318666220810161945. PMID: 35950255
Acute bronchiolitis: assessment and management in the emergency department.
Joseph MM, Edwards A
Pediatr Emerg Med Pract 2019 Oct;16(10):1-24. Epub 2019 Oct 2 PMID: 31557431
Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old.
Roqué i Figuls M, Giné-Garriga M, Granados Rugeles C, Perrotta C, Vilaró J
Cochrane Database Syst Rev 2016 Feb 1;2(2):CD004873. doi: 10.1002/14651858.CD004873.pub5. PMID: 26833493Free PMC Article

Prognosis

Comparison of severity scales for acute bronchiolitis in real clinical practice.
Granda E, Urbano M, Andrés P, Corchete M, Cano A, Velasco R
Eur J Pediatr 2023 Apr;182(4):1619-1626. Epub 2023 Jan 27 doi: 10.1007/s00431-023-04840-5. PMID: 36702906
Acute bronchiolitis during the COVID-19 pandemic.
Flores-Pérez P, Gerig N, Cabrera-López MI, de Unzueta-Roch JL, Del Rosal T, Calvo C; COVID-19 Study Group in Children
Enferm Infecc Microbiol Clin (Engl Ed) 2022 Dec;40(10):572-575. doi: 10.1016/j.eimce.2021.06.005. PMID: 36464475Free PMC Article
The relationship between immature platelet fraction and severity of acute bronchiolitis.
Doğan M, Köse M, Öztürk MA, Hangül M, Aslaner H
Turk J Pediatr 2021;63(6):1056-1063. doi: 10.24953/turkjped.2021.06.014. PMID: 35023656
'They said it was bronchiolitis; is it going to turn into asthma doctor?'.
Gidaris D, Urquhart D, Anthracopoulos MB
Respirology 2014 Nov;19(8):1158-64. Epub 2014 Aug 19 doi: 10.1111/resp.12371. PMID: 25138566
Bronchiolitis: update 2001.
Schlesinger C, Koss MN
Curr Opin Pulm Med 2002 Mar;8(2):112-6. doi: 10.1097/00063198-200203000-00006. PMID: 11845006

Clinical prediction guides

Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old.
Roqué-Figuls M, Giné-Garriga M, Granados Rugeles C, Perrotta C, Vilaró J
Cochrane Database Syst Rev 2023 Apr 3;4(4):CD004873. doi: 10.1002/14651858.CD004873.pub6. PMID: 37010196Free PMC Article
Comparison of severity scales for acute bronchiolitis in real clinical practice.
Granda E, Urbano M, Andrés P, Corchete M, Cano A, Velasco R
Eur J Pediatr 2023 Apr;182(4):1619-1626. Epub 2023 Jan 27 doi: 10.1007/s00431-023-04840-5. PMID: 36702906
Respiratory Syncytial Virus is the Most Common Causative Agent of Viral Bronchiolitis in Young Children: An Updated Review.
Hon KL, Leung AKC, Wong AHC, Dudi A, Leung KKY
Curr Pediatr Rev 2023;19(2):139-149. doi: 10.2174/1573396318666220810161945. PMID: 35950255
Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old.
Roqué i Figuls M, Giné-Garriga M, Granados Rugeles C, Perrotta C, Vilaró J
Cochrane Database Syst Rev 2016 Feb 1;2(2):CD004873. doi: 10.1002/14651858.CD004873.pub5. PMID: 26833493Free PMC Article
Bronchodilators for bronchiolitis.
Gadomski AM, Scribani MB
Cochrane Database Syst Rev 2014 Jun 17;2014(6):CD001266. doi: 10.1002/14651858.CD001266.pub4. PMID: 24937099Free PMC Article

Recent systematic reviews

Nebulised hypertonic saline solution for acute bronchiolitis in infants.
Zhang L, Mendoza-Sassi RA, Wainwright CE, Aregbesola A, Klassen TP
Cochrane Database Syst Rev 2023 Apr 4;4(4):CD006458. doi: 10.1002/14651858.CD006458.pub5. PMID: 37014057Free PMC Article
Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old.
Roqué-Figuls M, Giné-Garriga M, Granados Rugeles C, Perrotta C, Vilaró J
Cochrane Database Syst Rev 2023 Apr 3;4(4):CD004873. doi: 10.1002/14651858.CD004873.pub6. PMID: 37010196Free PMC Article
Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old.
Roqué i Figuls M, Giné-Garriga M, Granados Rugeles C, Perrotta C, Vilaró J
Cochrane Database Syst Rev 2016 Feb 1;2(2):CD004873. doi: 10.1002/14651858.CD004873.pub5. PMID: 26833493Free PMC Article
Bronchodilators for bronchiolitis.
Gadomski AM, Scribani MB
Cochrane Database Syst Rev 2014 Jun 17;2014(6):CD001266. doi: 10.1002/14651858.CD001266.pub4. PMID: 24937099Free PMC Article
Bronchodilators for bronchiolitis.
Gadomski AM, Brower M
Cochrane Database Syst Rev 2010 Dec 8;(12):CD001266. doi: 10.1002/14651858.CD001266.pub2. PMID: 21154348

Supplemental Content

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    Clinical resources

    Practice guidelines

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    Curated

    • NICE, 2021
      UK NICE Guideline NG9, Bronchiolitis in children: diagnosis and management, 2021

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
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      Related literature resources in PubMed

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