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Adult Acute Basophilic Leukemia

MedGen UID:
124637
•Concept ID:
C0279631
•
Neoplastic Process

Definition

An acute basophilic leukemia occurring in adults. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdult Acute Basophilic Leukemia

Recent clinical studies

Etiology

The tryptase positive compact round cell infiltrate of the bone marrow (TROCI-BM): a novel histopathological finding requiring the application of lineage specific markers.
Horny HP, Sotlar K, Stellmacher F, Krokowski M, Agis H, Schwartz LB, Valent P
J Clin Pathol 2006 Mar;59(3):298-302. doi: 10.1136/jcp.2005.028738. PMID: 16505282Free PMC Article
Acute erythroid neoplastic proliferations. A biological study based on 62 patients.
Domingo-Claros A, Larriba I, Rozman M, Irriguible D, Vallespí T, Aventin A, Ayats R, Millá F, Solé F, Florensa L, Gallart M, Tuset E, Lopez C, Woessner S
Haematologica 2002 Feb;87(2):148-53. PMID: 11836165
Morphology of acute promyelocytic leukemia with cytogenetic or molecular evidence for the diagnosis: characterization of additional microgranular variants.
Neame PB, Soamboonsrup P, Leber B, Carter RF, Sunisloe L, Patterson W, Orzel A, Bates S, McBride JA
Am J Hematol 1997 Nov;56(3):131-42. doi: 10.1002/(sici)1096-8652(199711)56:3<131::aid-ajh1>3.0.co;2-z. PMID: 9371524
Acute megakaryoblastic leukemia.
Gassmann W, Löffler H
Leuk Lymphoma 1995;18 Suppl 1:69-73. doi: 10.3109/10428199509075307. PMID: 7496359
Morphologic, immunologic and cytogenetic studies in erythroleukaemia: evidence for multilineage involvement and identification of two distinct cytogenetic-clinicopathological types.
Cuneo A, Van Orshoven A, Michaux JL, Boogaerts M, Louwagie A, Doyen C, Dal Cin P, Fagioli F, Castoldi G, Van den Berghe H
Br J Haematol 1990 Jul;75(3):346-54. doi: 10.1111/j.1365-2141.1990.tb04347.x. PMID: 2386768

Diagnosis

Diagnosis of rare subtypes of acute myeloid leukaemia and related neoplasms.
George TI, Bajel A
Pathology 2021 Apr;53(3):312-327. Epub 2021 Mar 4 doi: 10.1016/j.pathol.2021.02.001. PMID: 33676766
Use of a rat basophil leukemia (RBL) cell-based immunological assay for allergen identification, clinical diagnosis of allergy, and identification of anti-allergy agents for use in immunotherapy.
Sun N, Zhou C, Zhou X, Sun L, Che H
J Immunotoxicol 2015 Apr-Jun;12(2):199-205. Epub 2014 Jun 12 doi: 10.3109/1547691X.2014.920063. PMID: 24920006
Acute erythroid neoplastic proliferations. A biological study based on 62 patients.
Domingo-Claros A, Larriba I, Rozman M, Irriguible D, Vallespí T, Aventin A, Ayats R, Millá F, Solé F, Florensa L, Gallart M, Tuset E, Lopez C, Woessner S
Haematologica 2002 Feb;87(2):148-53. PMID: 11836165
Acute megakaryoblastic leukemia.
Gassmann W, Löffler H
Leuk Lymphoma 1995;18 Suppl 1:69-73. doi: 10.3109/10428199509075307. PMID: 7496359
Morphology and cytochemistry of acute lymphoblastic leukaemia.
Löffler H, Gassmann W
Baillieres Clin Haematol 1994 Jun;7(2):263-72. doi: 10.1016/s0950-3536(05)80202-1. PMID: 7803901

Therapy

Secondary basophilic leukemia in Ph-negative myeloid neoplasms: A distinct subset with poor prognosis.
Berger D, Bauer K, Kornauth C, Gamperl S, Stefanzl G, Smiljkovic D, Sillaber C, Bettelheim P, Knöbl P, Schiefer AI, Greiner G, Thalhammer R, Hoermann G, Schwarzinger I, Staber PB, Sperr WR, Valent P
Neoplasia 2021 Dec;23(12):1183-1191. Epub 2021 Oct 31 doi: 10.1016/j.neo.2021.09.010. PMID: 34731787Free PMC Article
Myeloid tumors accompanying systemic mastocytosis, basophilia, and abnormal platelet-derived growth factor receptor β: A case report.
Li Y, Jing Y, Wan H, Liu D
Medicine (Baltimore) 2021 Feb 26;100(8):e24707. doi: 10.1097/MD.0000000000024707. PMID: 33663081Free PMC Article
Acute basophilic leukemia.
Eveillard M, Desjonqueres A
Blood 2014 May 15;123(20):3071. doi: 10.1182/blood-2014-02-555698. PMID: 24949509
Acute basophilic leukemia.
Giagounidis AA, Hildebrandt B, Heinsch M, Germing U, Aivado M, Aul C
Eur J Haematol 2001 Aug;67(2):72-6. doi: 10.1034/j.1600-0609.2001.t01-1-00487.x. PMID: 11722593
A case of basophilic leukemia bearing simultaneous translocations t(8;21) and t(9;22).
Xue YQ, Guo Y, Lu DR, Gu J, Lu DW, Gong JX, Wang MH, Zhu WY, Lin BJ
Cancer Genet Cytogenet 1991 Feb;51(2):215-21. doi: 10.1016/0165-4608(91)90134-g. PMID: 1993306

Prognosis

Secondary basophilic leukemia in Ph-negative myeloid neoplasms: A distinct subset with poor prognosis.
Berger D, Bauer K, Kornauth C, Gamperl S, Stefanzl G, Smiljkovic D, Sillaber C, Bettelheim P, Knöbl P, Schiefer AI, Greiner G, Thalhammer R, Hoermann G, Schwarzinger I, Staber PB, Sperr WR, Valent P
Neoplasia 2021 Dec;23(12):1183-1191. Epub 2021 Oct 31 doi: 10.1016/j.neo.2021.09.010. PMID: 34731787Free PMC Article
Diagnosis of rare subtypes of acute myeloid leukaemia and related neoplasms.
George TI, Bajel A
Pathology 2021 Apr;53(3):312-327. Epub 2021 Mar 4 doi: 10.1016/j.pathol.2021.02.001. PMID: 33676766
Myeloid tumors accompanying systemic mastocytosis, basophilia, and abnormal platelet-derived growth factor receptor β: A case report.
Li Y, Jing Y, Wan H, Liu D
Medicine (Baltimore) 2021 Feb 26;100(8):e24707. doi: 10.1097/MD.0000000000024707. PMID: 33663081Free PMC Article
Acute basophilic leukemia.
Giagounidis AA, Hildebrandt B, Heinsch M, Germing U, Aivado M, Aul C
Eur J Haematol 2001 Aug;67(2):72-6. doi: 10.1034/j.1600-0609.2001.t01-1-00487.x. PMID: 11722593
CD56+CD7+ stem cell leukemia/lymphoma with D2-Jdelta1 rearrangement.
Yoshida T, Kimura N, Sawada H, Suematsu E, Nagano M, Akiyoshi T, Motomura S, Kikuchi M, Nishimura J, Tamura K
Intern Med 1999 Jul;38(7):547-55. PMID: 10435360

Clinical prediction guides

Myeloid tumors accompanying systemic mastocytosis, basophilia, and abnormal platelet-derived growth factor receptor β: A case report.
Li Y, Jing Y, Wan H, Liu D
Medicine (Baltimore) 2021 Feb 26;100(8):e24707. doi: 10.1097/MD.0000000000024707. PMID: 33663081Free PMC Article
Acute erythroid neoplastic proliferations. A biological study based on 62 patients.
Domingo-Claros A, Larriba I, Rozman M, Irriguible D, Vallespí T, Aventin A, Ayats R, Millá F, Solé F, Florensa L, Gallart M, Tuset E, Lopez C, Woessner S
Haematologica 2002 Feb;87(2):148-53. PMID: 11836165
Acute basophilic leukemia.
Giagounidis AA, Hildebrandt B, Heinsch M, Germing U, Aivado M, Aul C
Eur J Haematol 2001 Aug;67(2):72-6. doi: 10.1034/j.1600-0609.2001.t01-1-00487.x. PMID: 11722593
Acute promyelocytic leukemia: morphological and clinical features.
Invernizzi R, Iannone AM, Bernuzzi S, D'Alessio A, Fiamenghi C, Ippoliti G, Scagliosi S, Ascari E
Haematologica 1993 May-Jun;78(3):156-61. PMID: 8375744
Terminal deoxynucleotidyl transferase positive lymphoblastic lymphoma: a study of 15 cases.
Long JC, McCaffrey RP, Aisenberg AC, Marks SM, Kung PC
Cancer 1979 Dec;44(6):2127-39. doi: 10.1002/1097-0142(197912)44:6<2127::aid-cncr2820440625>3.0.co;2-g. PMID: 315816

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