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Downgaze palsy

MedGen UID:
1369087
•Concept ID:
C4476704
•
Disease or Syndrome
Synonyms: Downgaze paresis; Supranuclear downgaze palsy
 
HPO: HP:0025330

Definition

A limitation of the ability to direct one's gaze below the horizontal meridian. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDowngaze palsy

Professional guidelines

PubMed

The diagnosis and surgical management of acquired bilateral superior oblique palsy.
Price NC, Vickers S, Lee JP, Fells P
Eye (Lond) 1987;1 ( Pt 1):78-85. doi: 10.1038/eye.1987.12. PMID: 3556663
Diagnosis and treatment of thyroid myopathy.
Scott WE, Thalacker JA
Ophthalmology 1981 Jun;88(6):493-8. doi: 10.1016/s0161-6420(81)34988-4. PMID: 7267024

Recent clinical studies

Etiology

Neuro-Ophthalmologic Features and Outcomes of Thalamic Infarction: A Single-Institutional 10-Year Experience.
Moon Y, Eah KS, Lee EJ, Kang DW, Kwon SU, Kim JS, Lim HT
J Neuroophthalmol 2021 Mar 1;41(1):29-36. doi: 10.1097/WNO.0000000000000864. PMID: 31851027
Transient selective downward gaze paralysis complicating posterior fossa tumor resection in children. Report of 2 cases.
Chern JJ, Relyea K, Edmond JC, Whitehead WE, Curry DJ, Luerssen TG, Jea A
J Neurosurg Pediatr 2009 Jun;3(6):467-71. doi: 10.3171/2009.2.PEDS08446. PMID: 19485729

Diagnosis

Using Downgaze Palsy Progression Rate to Model Survival in Progressive Supranuclear Palsy-Richardson Syndrome.
Xie T, Wills AM, Liao C, Dale ML, Ramsden DB, Padmanaban M, Abou Chaar W, Pantelyat A, Golbe LI
Mov Disord 2023 Feb;38(2):304-312. Epub 2022 Dec 27 doi: 10.1002/mds.29299. PMID: 36573662
Neuro-Ophthalmologic Features and Outcomes of Thalamic Infarction: A Single-Institutional 10-Year Experience.
Moon Y, Eah KS, Lee EJ, Kang DW, Kwon SU, Kim JS, Lim HT
J Neuroophthalmol 2021 Mar 1;41(1):29-36. doi: 10.1097/WNO.0000000000000864. PMID: 31851027
Transient selective downward gaze paralysis complicating posterior fossa tumor resection in children. Report of 2 cases.
Chern JJ, Relyea K, Edmond JC, Whitehead WE, Curry DJ, Luerssen TG, Jea A
J Neurosurg Pediatr 2009 Jun;3(6):467-71. doi: 10.3171/2009.2.PEDS08446. PMID: 19485729
Neuro-ophthalmic findings in progressive supranuclear palsy.
Friedman DI, Jankovic J, McCrary JA 3rd
J Clin Neuroophthalmol 1992 Jun;12(2):104-9. PMID: 1629370
Impairment of vertical motion detection and downgaze palsy due to rostral midbrain infarction.
Heide W, Fahle M, Koenig E, Dichgans J, Schroth G
J Neurol 1990 Nov;237(7):432-40. doi: 10.1007/BF00314736. PMID: 2273413

Prognosis

Using Downgaze Palsy Progression Rate to Model Survival in Progressive Supranuclear Palsy-Richardson Syndrome.
Xie T, Wills AM, Liao C, Dale ML, Ramsden DB, Padmanaban M, Abou Chaar W, Pantelyat A, Golbe LI
Mov Disord 2023 Feb;38(2):304-312. Epub 2022 Dec 27 doi: 10.1002/mds.29299. PMID: 36573662
Neuro-Ophthalmologic Features and Outcomes of Thalamic Infarction: A Single-Institutional 10-Year Experience.
Moon Y, Eah KS, Lee EJ, Kang DW, Kwon SU, Kim JS, Lim HT
J Neuroophthalmol 2021 Mar 1;41(1):29-36. doi: 10.1097/WNO.0000000000000864. PMID: 31851027

Clinical prediction guides

Using Downgaze Palsy Progression Rate to Model Survival in Progressive Supranuclear Palsy-Richardson Syndrome.
Xie T, Wills AM, Liao C, Dale ML, Ramsden DB, Padmanaban M, Abou Chaar W, Pantelyat A, Golbe LI
Mov Disord 2023 Feb;38(2):304-312. Epub 2022 Dec 27 doi: 10.1002/mds.29299. PMID: 36573662

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