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Abnormal cell morphology

MedGen UID:
1371574
•Concept ID:
C4476793
•
Anatomical Abnormality
HPO: HP:0025461

Definition

Any anomaly of cell structure. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal cell morphology

Professional guidelines

PubMed

Therapy-related myeloid neoplasms after treatment for ovarian cancer: A retrospective single-center case series.
Matsuoka A, Tate S, Nishikimi K, Otsuka S, Usui H, Tajima S, Habu Y, Nakamura N, Okuya R, Katayama E, Shozu M, Inaba Y, Koga K
J Obstet Gynaecol Res 2024 Jul;50(7):1148-1154. Epub 2024 Apr 17 doi: 10.1111/jog.15954. PMID: 38634254

Recent clinical studies

Etiology

Therapy-related myeloid neoplasms after treatment for ovarian cancer: A retrospective single-center case series.
Matsuoka A, Tate S, Nishikimi K, Otsuka S, Usui H, Tajima S, Habu Y, Nakamura N, Okuya R, Katayama E, Shozu M, Inaba Y, Koga K
J Obstet Gynaecol Res 2024 Jul;50(7):1148-1154. Epub 2024 Apr 17 doi: 10.1111/jog.15954. PMID: 38634254
DNA Methylation in Ovarian Tumors-a Comparison Between Fresh Tissue and FFPE Samples.
Oliveira DVNP, Hentze J, O'Rourke CJ, Andersen JB, Høgdall C, Høgdall EV
Reprod Sci 2021 Nov;28(11):3212-3218. Epub 2021 Apr 23 doi: 10.1007/s43032-021-00589-0. PMID: 33891290Free PMC Article
Genetic basis of myelodysplastic syndromes.
Ogawa S
Proc Jpn Acad Ser B Phys Biol Sci 2020;96(3):107-121. doi: 10.2183/pjab.96.009. PMID: 32161209Free PMC Article
TMEM10 Promotes Oligodendrocyte Differentiation and is Expressed by Oligodendrocytes in Human Remyelinating Multiple Sclerosis Plaques.
de Faria O Jr, Dhaunchak AS, Kamen Y, Roth AD, Kuhlmann T, Colman DR, Kennedy TE
Sci Rep 2019 Mar 5;9(1):3606. doi: 10.1038/s41598-019-40342-x. PMID: 30837646Free PMC Article
Hydroxycamptothecin-induced apoptosis in hepatoma SMMC-7721 cells and the role of mitochondrial pathway.
Fu YR, Yi ZJ, Yan YR, Qiu ZY
Mitochondrion 2006 Aug;6(4):211-7. Epub 2006 Aug 1 doi: 10.1016/j.mito.2006.07.005. PMID: 16926123

Diagnosis

The role of blood cell morphology in understanding and diagnosing severe fever with thrombocytopenia syndrome (SFTS): Insights from a case report.
Gu K, Gao J, He L, Lu Z, Zhang Y
Medicine (Baltimore) 2024 Nov 8;103(45):e40502. doi: 10.1097/MD.0000000000040502. PMID: 39533577Free PMC Article
Therapy-related myeloid neoplasms after treatment for ovarian cancer: A retrospective single-center case series.
Matsuoka A, Tate S, Nishikimi K, Otsuka S, Usui H, Tajima S, Habu Y, Nakamura N, Okuya R, Katayama E, Shozu M, Inaba Y, Koga K
J Obstet Gynaecol Res 2024 Jul;50(7):1148-1154. Epub 2024 Apr 17 doi: 10.1111/jog.15954. PMID: 38634254
Circ_0004535/miR-1827/CASP8 network involved in type 2 diabetes mellitus with nonalcoholic fatty liver disease.
Li M, Zeng A, Tang X, Xu H, Xiong W, Guo Y
Sci Rep 2023 Nov 13;13(1):19807. doi: 10.1038/s41598-023-47189-3. PMID: 37957232Free PMC Article
Surface chemistry but not aspect ratio mediates the biological toxicity of gold nanorods in vitro and in vivo.
Wan J, Wang JH, Liu T, Xie Z, Yu XF, Li W
Sci Rep 2015 Jun 22;5:11398. doi: 10.1038/srep11398. PMID: 26096816Free PMC Article
Monocytes and macrophages as biomarkers for the diagnosis of megalencephalic leukoencephalopathy with subcortical cysts.
Petrini S, Minnone G, Coccetti M, Frank C, Aiello C, Cutarelli A, Ambrosini E, Lanciotti A, Brignone MS, D'Oria V, Strippoli R, De Benedetti F, Bertini E, Bracci-Laudiero L
Mol Cell Neurosci 2013 Sep;56:307-21. Epub 2013 Jul 10 doi: 10.1016/j.mcn.2013.07.001. PMID: 23851226

Therapy

Therapy-related myeloid neoplasms after treatment for ovarian cancer: A retrospective single-center case series.
Matsuoka A, Tate S, Nishikimi K, Otsuka S, Usui H, Tajima S, Habu Y, Nakamura N, Okuya R, Katayama E, Shozu M, Inaba Y, Koga K
J Obstet Gynaecol Res 2024 Jul;50(7):1148-1154. Epub 2024 Apr 17 doi: 10.1111/jog.15954. PMID: 38634254
The adverse effect of anticancer drug toremifene on vascular smooth muscle cells is an important aspect of its tumor growth inhibition.
Wang H, Liu J, Wang M, Yang C, Wang G, Hu T
J Cancer Res Clin Oncol 2023 Aug;149(10):7837-7848. Epub 2023 Apr 10 doi: 10.1007/s00432-023-04744-9. PMID: 37036506
Different cell death mechanisms are induced by a hydrophobic flavin in human tumor cells after visible light irradiation.
Muñoz MA, Pacheco A, Becker MI, Silva E, Ebensperger R, Garcia AM, De Ioannes AE, Edwards AM
J Photochem Photobiol B 2011 Apr 4;103(1):57-67. Epub 2011 Jan 19 doi: 10.1016/j.jphotobiol.2011.01.012. PMID: 21306911
Therapy-related myelodysplastic syndrome following cyclophosphamide pulse and/or methotrexate therapy in a patient with systemic lupus erythematosus.
Iwadate H, Kobayashi H, Yano K, Watanabe H, Ikeda K, Ogawa K, Ohira H
Fukushima J Med Sci 2010 Dec;56(2):121-7. doi: 10.5387/fms.56.121. PMID: 21502712
Aneuploidy, the somatic mutation that makes cancer a species of its own.
Duesberg P, Rasnick D
Cell Motil Cytoskeleton 2000 Oct;47(2):81-107. doi: 10.1002/1097-0169(200010)47:2<81::AID-CM1>3.0.CO;2-#. PMID: 11013390

Prognosis

The role of blood cell morphology in understanding and diagnosing severe fever with thrombocytopenia syndrome (SFTS): Insights from a case report.
Gu K, Gao J, He L, Lu Z, Zhang Y
Medicine (Baltimore) 2024 Nov 8;103(45):e40502. doi: 10.1097/MD.0000000000040502. PMID: 39533577Free PMC Article
Therapy-related myeloid neoplasms after treatment for ovarian cancer: A retrospective single-center case series.
Matsuoka A, Tate S, Nishikimi K, Otsuka S, Usui H, Tajima S, Habu Y, Nakamura N, Okuya R, Katayama E, Shozu M, Inaba Y, Koga K
J Obstet Gynaecol Res 2024 Jul;50(7):1148-1154. Epub 2024 Apr 17 doi: 10.1111/jog.15954. PMID: 38634254
Circ_0004535/miR-1827/CASP8 network involved in type 2 diabetes mellitus with nonalcoholic fatty liver disease.
Li M, Zeng A, Tang X, Xu H, Xiong W, Guo Y
Sci Rep 2023 Nov 13;13(1):19807. doi: 10.1038/s41598-023-47189-3. PMID: 37957232Free PMC Article
Genetic basis of myelodysplastic syndromes.
Ogawa S
Proc Jpn Acad Ser B Phys Biol Sci 2020;96(3):107-121. doi: 10.2183/pjab.96.009. PMID: 32161209Free PMC Article
A unifying model for reconstructing radiosensitivity from micronucleus formation, apoptosis and abnormal morphology.
Akudugu JM, Abend M, Böhm L
Radiat Environ Biophys 2002 Dec;41(4):267-74. Epub 2002 Dec 20 doi: 10.1007/s00411-002-0176-1. PMID: 12541072

Clinical prediction guides

Circ_0004535/miR-1827/CASP8 network involved in type 2 diabetes mellitus with nonalcoholic fatty liver disease.
Li M, Zeng A, Tang X, Xu H, Xiong W, Guo Y
Sci Rep 2023 Nov 13;13(1):19807. doi: 10.1038/s41598-023-47189-3. PMID: 37957232Free PMC Article
Antimicrobial and anti-biofilm activity of thymoquinone against Shigella flexneri.
Fan Q, Yuan Y, Jia H, Zeng X, Wang Z, Hu Z, Gao Z, Yue T
Appl Microbiol Biotechnol 2021 Jun;105(11):4709-4718. Epub 2021 May 20 doi: 10.1007/s00253-021-11295-x. PMID: 34014346
Pbx proteins in Cryptococcus neoformans cell wall remodeling and capsule assembly.
Kumar P, Heiss C, Santiago-Tirado FH, Black I, Azadi P, Doering TL
Eukaryot Cell 2014 May;13(5):560-71. Epub 2014 Feb 28 doi: 10.1128/EC.00290-13. PMID: 24585882Free PMC Article
Monocytes and macrophages as biomarkers for the diagnosis of megalencephalic leukoencephalopathy with subcortical cysts.
Petrini S, Minnone G, Coccetti M, Frank C, Aiello C, Cutarelli A, Ambrosini E, Lanciotti A, Brignone MS, D'Oria V, Strippoli R, De Benedetti F, Bertini E, Bracci-Laudiero L
Mol Cell Neurosci 2013 Sep;56:307-21. Epub 2013 Jul 10 doi: 10.1016/j.mcn.2013.07.001. PMID: 23851226
Different cell death mechanisms are induced by a hydrophobic flavin in human tumor cells after visible light irradiation.
Muñoz MA, Pacheco A, Becker MI, Silva E, Ebensperger R, Garcia AM, De Ioannes AE, Edwards AM
J Photochem Photobiol B 2011 Apr 4;103(1):57-67. Epub 2011 Jan 19 doi: 10.1016/j.jphotobiol.2011.01.012. PMID: 21306911

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