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Malignant Trophoblastic Teratoma

MedGen UID:
137778
•Concept ID:
C0334528
•
Neoplastic Process
Synonyms: Malignant teratoma, trophoblastic; Trophoblastic malignant teratoma
SNOMED CT: Malignant teratoma, trophoblastic (65646006); Trophoblastic malignant teratoma (65646006)

Definition

A malignant germ cell tumor which metastasizes widely and produces high levels of human chorionic gonadotropin. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant Trophoblastic Teratoma

Professional guidelines

PubMed

Ovarian germ cell malignancy: a heterogeneous tumour requiring supra-regional management.
Luis IV, Coleman R
Eur J Gynaecol Oncol 2011;32(4):387-92. PMID: 21941958
Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues.
Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467
Treatment of malignant ovarian germ cell tumors: response to vincristine, dactinomycin, and cyclophosphamide (preliminary report).
Slayton RE, Hreshchyshyn MM, Silverberg SC, Shingleton HM, Park RC, DiSalia PJ, Blessing JA
Cancer 1978 Aug;42(2):390-8. doi: 10.1002/1097-0142(197808)42:2<390::aid-cncr2820420203>3.0.co;2-z. PMID: 679144

Recent clinical studies

Diagnosis

Hurricane growth of malignant trophoblastic teratoma.
Raja MA, Oliver RT, Blomley M
Postgrad Med J 1993 Jun;69(812):472-3. doi: 10.1136/pgmj.69.812.472. PMID: 7516075Free PMC Article

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