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Charles bonnet syndrome

MedGen UID:
137926
Concept ID:
C0339731
Disease or Syndrome
Synonym: Charles Bonnet Syndrome
SNOMED CT: Charles Bonnet syndrome (193756007)
 
Monarch Initiative: MONDO:0022140

Definition

Charles Bonnet syndrome (CBS) refers to the presenceof visual hallucinations in individuals with visual acuity loss without havingpsychosis or dementia. The condition is likely caused by the brain continuing to interpret images, even in their absence. Underlying conditions of vision loss associated with Charles Bonnet syndrome are diverse (including conditions such as macular degeneration and stroke) and may affect the eye, optic nerve, or brain. Hallucinations often resolve if the underlying vision deficit is corrected and can also remit in some individuals with static or progressive vision loss. Treatment is individualized. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCharles bonnet syndrome

Professional guidelines

PubMed

Eren OE, Wilhelm H, Schankin CJ, Straube A
Dtsch Arztebl Int 2021 Oct 1;118(39):647-653. doi: 10.3238/arztebl.m2021.0287. PMID: 34636719Free PMC Article
Santos-Bueso E, Porta-Etessam J
Arch Soc Esp Oftalmol 2016 Nov;91(11):511-512. Epub 2016 Aug 16 doi: 10.1016/j.oftal.2016.07.005. PMID: 27542522
Hughes DF
J Psychiatr Ment Health Nurs 2013 Mar;20(2):169-75. Epub 2012 Mar 27 doi: 10.1111/j.1365-2850.2012.01904.x. PMID: 22452327

Recent clinical studies

Therapy

Risi E, Bagla P, Allen L, Das A
Prim Care Companion CNS Disord 2023 Nov 9;25(6) doi: 10.4088/PCC.23cr03545. PMID: 37976227
Marmamula S, Sumalini R, Reddy TK, Brahmanandam SM, Satgunam P
Clin Exp Optom 2020 Nov;103(6):865-869. Epub 2019 Dec 3 doi: 10.1111/cxo.13015. PMID: 31797429
Cammaroto S, D'Aleo G, Smorto C, Bramanti P
Funct Neurol 2008 Jul-Sep;23(3):123-7. PMID: 19152731
Evers S
Curr Psychiatry Rep 2006 Jun;8(3):205-10. doi: 10.1007/s11920-006-0024-0. PMID: 19817070
Bhatia MS, Khastgir U, Malik SC
Br J Psychiatry 1992 Sep;161:409-10. doi: 10.1192/bjp.161.3.409. PMID: 1393314

Prognosis

Christoph SEG, Boden KT, Pütz A, Januschowski K, Siegel R, Seitz B, Szurman P, Schulz A
Int Ophthalmol 2024 Sep 10;44(1):375. doi: 10.1007/s10792-024-03298-0. PMID: 39256212Free PMC Article
Carpenter K, Jolly JK, Bridge H
Ophthalmic Physiol Opt 2019 Nov;39(6):414-421. Epub 2019 Oct 8 doi: 10.1111/opo.12645. PMID: 31591762
Russell G, Harper R, Allen H, Baldwin R, Burns A
Int J Geriatr Psychiatry 2018 Jan;33(1):39-46. Epub 2017 Jan 24 doi: 10.1002/gps.4665. PMID: 28117918
Stojanov O
Vojnosanit Pregl 2016 Sep;73(9):881-4. doi: 10.2298/VSP150321140S. PMID: 29320624
Cox TM, ffytche DH
Br J Ophthalmol 2014 Sep;98(9):1236-9. Epub 2014 May 13 doi: 10.1136/bjophthalmol-2014-304920. PMID: 24825847Free PMC Article

Clinical prediction guides

Dhooge PPA, Teunisse RJ, Liefers B, Lambertus S, Bax NM, Hoyng CB, Cruysberg JRM, Klevering BJ
Br J Ophthalmol 2023 Feb;107(2):248-253. Epub 2021 Aug 4 doi: 10.1136/bjophthalmol-2021-319525. PMID: 34348923
Firbank MJ, daSilva Morgan K, Collerton D, Elder GJ, Parikh J, Olsen K, Schumacher J, Ffytche D, Taylor JP
Neuroimage Clin 2022;35:103041. Epub 2022 May 11 doi: 10.1016/j.nicl.2022.103041. PMID: 35576854Free PMC Article
Stojanov O
Vojnosanit Pregl 2016 Sep;73(9):881-4. doi: 10.2298/VSP150321140S. PMID: 29320624
Lapid MI, Burton MC, Chang MT, Rummans TA, Cha SS, Leavitt JA, Boeve BF
J Geriatr Psychiatry Neurol 2013 Mar;26(1):3-9. Epub 2013 Feb 4 doi: 10.1177/0891988712473800. PMID: 23385362
Pliskin NH, Kiolbasa TA, Towle VL, Pankow L, Ernest JT, Noronha A, Luchins DJ
J Am Geriatr Soc 1996 Sep;44(9):1055-61. doi: 10.1111/j.1532-5415.1996.tb02937.x. PMID: 8790230

Recent systematic reviews

Blom JD
Neurosci Biobehav Rev 2021 Jun;125:627-636. Epub 2021 Mar 4 doi: 10.1016/j.neubiorev.2021.03.002. PMID: 33676962
Subhi Y, Schmidt DC, Bach-Holm D, Kolko M, Singh A
Acta Ophthalmol 2021 Mar;99(2):128-133. Epub 2020 Aug 4 doi: 10.1111/aos.14567. PMID: 32749787
Niazi S, Krogh Nielsen M, Singh A, Sørensen TL, Subhi Y
Acta Ophthalmol 2020 Mar;98(2):121-131. Epub 2019 Oct 26 doi: 10.1111/aos.14287. PMID: 31654492

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