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Cutaneous granular cell tumor

MedGen UID:
138035
•Concept ID:
C0346060
•
Neoplastic Process
Synonyms: Abrikossoff's tumor of skin; Cutaneous Granular Cell Neoplasm; cutaneous granular cell neoplasm; Cutaneous Granular Cell Tumor; cutaneous granular cell tumor; Granular cell myoblastoma of skin; Granular Cell Neoplasm of Skin; granular cell neoplasm of skin; Granular Cell Neoplasm of the Skin; granular cell neoplasm of the skin; Granular Cell Skin Tumor; granular cell skin tumor; granular cell skin tumour; Granular cell tumor of skin; Granular Cell Tumor of Skin; granular cell tumor of skin; Granular Cell Tumor of the Skin; granular cell tumor of the skin; granular cell tumor of zone of skin; granular cell tumour of skin; granular cell tumour of the skin; granular cell tumour of zone of skin; Skin Granular Cell Neoplasm; skin granular cell neoplasm; skin granular cell tumor; skin granular cell tumour; zone of skin granular cell tumor; zone of skin granular cell tumour
SNOMED CT: Granular cell myoblastoma of skin (254763007); Abrikossoff's tumor of skin (254763007); Granular cell tumor of skin (254763007)
 
Monarch Initiative: MONDO:0002291

Definition

A granular cell tumor that involves the zone of skin. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCutaneous granular cell tumor

Professional guidelines

PubMed

Newly Diagnosed Sellar Tumors in Patients with Cancer: A Diagnostic Challenge and Management Dilemma.
Goulart CR, Upadhyay S, Ditzel Filho LFS, Beer-Furlan A, Carrau RL, Prevedello LM, Prevedello DM
World Neurosurg 2017 Oct;106:254-265. Epub 2017 Jun 30 doi: 10.1016/j.wneu.2017.06.139. PMID: 28673886
Guidelines for NHL: updates to the management of diffuse large B-cell lymphoma and new guidelines for primary cutaneous CD30+ T-cell lymphoproliferative disorders and T-cell large granular lymphocytic leukemia.
Zelenetz AD
J Natl Compr Canc Netw 2014 May;12(5 Suppl):797-800. doi: 10.6004/jnccn.2014.0193. PMID: 24853220
HMB-45 and Melan-A are useful in the differential diagnosis between granular cell tumor and malignant melanoma.
Gleason BC, Nascimento AF
Am J Dermatopathol 2007 Feb;29(1):22-7. doi: 10.1097/01.dad.0000249888.41884.6c. PMID: 17284958

Recent clinical studies

Etiology

Multifocal Cutaneous Granular Cell Tumor in Children: A Rare Entity.
El-Khalawany M, Rageh MA, Hassab-El-Naby HMM
Am J Dermatopathol 2022 Jan 1;44(1):7-16. doi: 10.1097/DAD.0000000000002088. PMID: 34783707
Granular Cell Tumor on the Chest of a 9-Year-Old Female: Case Report and a Retrospective Analysis.
Al-Dawsari NA, Amra N
J Cutan Med Surg 2015 May-Jun;19(3):328-30. Epub 2015 Mar 13 doi: 10.2310/7750.2014.14140. PMID: 25775653

Diagnosis

A rare case of cutaneous granular cell tumor with unusual Melan-A expression in a child.
Cheng NH, Smith D, Errickson C, Ashi S
J Cutan Pathol 2024 Jun;51(6):434-438. Epub 2024 Mar 25 doi: 10.1111/cup.14619. PMID: 38527927
Multifocal Cutaneous Granular Cell Tumor in Children: A Rare Entity.
El-Khalawany M, Rageh MA, Hassab-El-Naby HMM
Am J Dermatopathol 2022 Jan 1;44(1):7-16. doi: 10.1097/DAD.0000000000002088. PMID: 34783707
Cutaneous granular cell tumor clinically mimicking ectopic breast diagnosed on fine needle aspiration cytology.
Keloth T, Sreerekha J, Gochhait D, Kekade S, Siddaraju N, Sistla S
Diagn Cytopathol 2019 Apr;47(4):337-340. Epub 2018 Dec 18 doi: 10.1002/dc.24124. PMID: 30561159
Granular Cell Tumor on the Chest of a 9-Year-Old Female: Case Report and a Retrospective Analysis.
Al-Dawsari NA, Amra N
J Cutan Med Surg 2015 May-Jun;19(3):328-30. Epub 2015 Mar 13 doi: 10.2310/7750.2014.14140. PMID: 25775653
Cutaneous granular cell tumor with epidermal involvement: a potential mimic of melanocytic neoplasia.
Ray S, Jukic DM
J Cutan Pathol 2007 Feb;34(2):188-94. doi: 10.1111/j.1600-0560.2006.00598.x. PMID: 17244032

Supplemental Content

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