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Primary intralymphatic angioendothelioma

MedGen UID:
138037
Concept ID:
C0346087
Neoplastic Process
Synonyms: Dabska tumor; Dabska Tumor; Dabska tumour; Endovascular papillary angioendothelioma; Malignant Endothelial Papillary Angioendothelioma; malignant endothelial papillary angioendothelioma; Papillary Endovascular Angioendothelioma; papillary Endovascular angioendothelioma; Papillary intralymphatic angioendomethelioma; Papillary Intralymphatic Angioendothelioma; Papillary intralymphatic angioendothelioma; papillary intralymphatic angioendothelioma; pila; primary intralymphatic angioendothelioma
SNOMED CT: Dabska tumor (128768006); Endovascular papillary angioendothelioma (128768006); Papillary intralymphatic angioendomethelioma (128768006); Endovascular papillary angioendothelioma (1231180000); Dabska tumor (1231180000); Primary intralymphatic angioendothelioma (1231180000); Papillary intralymphatic angioendothelioma (128768006); Papillary intralymphatic angioendothelioma (1231180000)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0018714
Orphanet: ORPHA458768

Definition

A rare vascular tumour characterised by an ill-defined, slowly growing, asymptomatic cutaneous plaque or nodule mostly involving the limbs, in fewer cases the trunk. The tumour is composed of lymphatic-like channels with prominent intraluminal papillary tufts with hyaline cores lined by hobnail endothelial cells. It is locally aggressive, while metastasis is rare. Infants and children are much more often affected than adults. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPrimary intralymphatic angioendothelioma

Recent clinical studies

Etiology

Righi A, Sbaraglia M, Gambarotti M, Gibertoni D, Rovira MP, Benini S, Errani C, Brenca M, Maestro R, Dei Tos AP
Am J Surg Pathol 2020 Sep;44(9):1192-1203. doi: 10.1097/PAS.0000000000001487. PMID: 32271190
Albertini AF, Brousse N, Bodemer C, Calonje E, Fraitag S
Am J Dermatopathol 2011 Oct;33(7):e84-7. doi: 10.1097/DAD.0b013e31821b0a9f. PMID: 21915027

Diagnosis

Pozo-Kreilinger JJ, Pena-Burgos EM, Ortiz-Cruz EJ, Cordero-García JM, Barrientos Ruiz I, Tapia-Viñe M, Peleteiro-Pensado M, Bernabéu-Taboada D
Skeletal Radiol 2026 Jan;54(1):125-130. Epub 2024 Apr 15 doi: 10.1007/s00256-024-04674-8. PMID: 38619614
Righi A, Sbaraglia M, Gambarotti M, Gibertoni D, Rovira MP, Benini S, Errani C, Brenca M, Maestro R, Dei Tos AP
Am J Surg Pathol 2020 Sep;44(9):1192-1203. doi: 10.1097/PAS.0000000000001487. PMID: 32271190
Li B, Li Y, Tian XY, Li Z
Diagn Pathol 2013 Sep 24;8:160. doi: 10.1186/1746-1596-8-160. PMID: 24063649Free PMC Article
Albertini AF, Brousse N, Bodemer C, Calonje E, Fraitag S
Am J Dermatopathol 2011 Oct;33(7):e84-7. doi: 10.1097/DAD.0b013e31821b0a9f. PMID: 21915027

Therapy

Albertini AF, Brousse N, Bodemer C, Calonje E, Fraitag S
Am J Dermatopathol 2011 Oct;33(7):e84-7. doi: 10.1097/DAD.0b013e31821b0a9f. PMID: 21915027

Prognosis

Righi A, Sbaraglia M, Gambarotti M, Gibertoni D, Rovira MP, Benini S, Errani C, Brenca M, Maestro R, Dei Tos AP
Am J Surg Pathol 2020 Sep;44(9):1192-1203. doi: 10.1097/PAS.0000000000001487. PMID: 32271190
Li B, Li Y, Tian XY, Li Z
Diagn Pathol 2013 Sep 24;8:160. doi: 10.1186/1746-1596-8-160. PMID: 24063649Free PMC Article

Clinical prediction guides

Righi A, Sbaraglia M, Gambarotti M, Gibertoni D, Rovira MP, Benini S, Errani C, Brenca M, Maestro R, Dei Tos AP
Am J Surg Pathol 2020 Sep;44(9):1192-1203. doi: 10.1097/PAS.0000000000001487. PMID: 32271190
Li B, Li Y, Tian XY, Li Z
Diagn Pathol 2013 Sep 24;8:160. doi: 10.1186/1746-1596-8-160. PMID: 24063649Free PMC Article

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