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Annular cutaneous lesion

MedGen UID:
1391698
•Concept ID:
C4476833
•
Finding
HPO: HP:0025528

Definition

A lesion of the skin with a ring-like distribution. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnnular cutaneous lesion

Conditions with this feature

Proteasome-associated autoinflammatory syndrome 2
MedGen UID:
1648482
•Concept ID:
C4747989
•
Disease or Syndrome
Proteasome-associated autoinflammatory syndrome-2 (PRAAS2) is an autosomal dominant disorder with onset in early infancy. Affected individuals develop severe inflammatory neutrophilic dermatitis, autoimmunity, and variable immunodeficiency (summary by Poli et al., 2018). For a discussion of genetic heterogeneity of PRAAS, see PRAAS1 (256040).
See: Condition Record
Proteasome-associated autoinflammatory syndrome 2

Professional guidelines

PubMed

Annular Lesions: Diagnosis and Treatment.
Trayes KP, Savage K, Studdiford JS
Am Fam Physician 2018 Sep 1;98(5):283-291. PMID: 30216021
Clinical and histopathological differential diagnosis of eosinophilic pustular folliculitis.
Fujiyama T, Tokura Y
J Dermatol 2013 Jun;40(6):419-23. Epub 2013 Mar 12 doi: 10.1111/1346-8138.12125. PMID: 23488969
Differential diagnosis of annular lesions.
Hsu S, Le EH, Khoshevis MR
Am Fam Physician 2001 Jul 15;64(2):289-96. PMID: 11476274

Recent clinical studies

Etiology

Granulomatous annular diseases.
Uzuncakmak TK, Durdu M, Karadag AS
Clin Dermatol 2023 May-Jun;41(3):355-367. Epub 2023 Jul 17 doi: 10.1016/j.clindermatol.2023.07.004. PMID: 37467899
Annular vasculitic lesions.
Wang HY, Robson DC, Kim SJ
Clin Dermatol 2023 May-Jun;41(3):326-339. Epub 2023 Jul 8 doi: 10.1016/j.clindermatol.2023.07.002. PMID: 37423264
Papulosquamous annular diseases.
Aslan Kayıran M, Wang JV, Karadag AS
Clin Dermatol 2022 Sep-Oct;40(5):441-449. Epub 2022 Jan 1 doi: 10.1016/j.clindermatol.2021.12.007. PMID: 34979266
Suspected inflammatory rheumatic diseases in patients presenting with skin rashes.
Alves F, Gonçalo M
Best Pract Res Clin Rheumatol 2019 Aug;33(4):101440. Epub 2019 Oct 1 doi: 10.1016/j.berh.2019.101440. PMID: 31585842
Annular erythema in primary Sjogren's syndrome: description of 43 non-Asian cases.
Brito-Zerón P, Retamozo S, Akasbi M, Gandía M, Perez-De-Lis M, Soto-Cardenas MJ, Diaz-Lagares C, Kostov B, Bove A, Bosch X, Perez-Alvarez R, Siso A, Ramos-Casals M
Lupus 2014 Feb;23(2):166-75. Epub 2013 Dec 10 doi: 10.1177/0961203313515764. PMID: 24326481

Diagnosis

Granulomatous annular diseases.
Uzuncakmak TK, Durdu M, Karadag AS
Clin Dermatol 2023 May-Jun;41(3):355-367. Epub 2023 Jul 17 doi: 10.1016/j.clindermatol.2023.07.004. PMID: 37467899
Annular vasculitic lesions.
Wang HY, Robson DC, Kim SJ
Clin Dermatol 2023 May-Jun;41(3):326-339. Epub 2023 Jul 8 doi: 10.1016/j.clindermatol.2023.07.002. PMID: 37423264
Annular lichenoid diseases.
McNally MA, Farooq S, Brown AE, Rees A, Hsu S, Motaparthi K
Clin Dermatol 2022 Sep-Oct;40(5):466-479. Epub 2021 Dec 31 doi: 10.1016/j.clindermatol.2021.12.009. PMID: 34979268
Annular infectious dermatoses.
Liu WT, Sun PL, Bramono K, Ezmerli M, Yang CC, Chen W
Clin Dermatol 2022 Sep-Oct;40(5):427-440. Epub 2021 Dec 31 doi: 10.1016/j.clindermatol.2021.12.006. PMID: 34974106
Annular Lesions: Diagnosis and Treatment.
Trayes KP, Savage K, Studdiford JS
Am Fam Physician 2018 Sep 1;98(5):283-291. PMID: 30216021

Therapy

Sarcoidosis: A great imitator.
Karadağ AS, Parish LC
Clin Dermatol 2019 May-Jun;37(3):240-254. Epub 2019 Jan 15 doi: 10.1016/j.clindermatol.2019.01.005. PMID: 31178106
Atypical presentations of cutaneous leishmaniasis: A systematic review.
Meireles CB, Maia LC, Soares GC, Teodoro IPP, Gadelha MDSV, da Silva CGL, de Lima MAP
Acta Trop 2017 Aug;172:240-254. Epub 2017 May 17 doi: 10.1016/j.actatropica.2017.05.022. PMID: 28526427
A Review of Annular Eruptions in Children.
Todd PS, Orlowski T, Schumacher-Kim W
Pediatr Ann 2015 Aug;44(8):e199-204. doi: 10.3928/00904481-20150812-09. PMID: 26312594
Drug-induced lupus erythematosus.
Marzano AV, Tavecchio S, Menicanti C, Crosti C
G Ital Dermatol Venereol 2014 Jun;149(3):301-9. PMID: 24819757
Nodular secondary syphilis.
Dave S, Gopinath DV, Thappa DM
Dermatol Online J 2003 Feb;9(1):9. PMID: 12639467

Prognosis

Suspected inflammatory rheumatic diseases in patients presenting with skin rashes.
Alves F, Gonçalo M
Best Pract Res Clin Rheumatol 2019 Aug;33(4):101440. Epub 2019 Oct 1 doi: 10.1016/j.berh.2019.101440. PMID: 31585842
Sarcoidosis: A great imitator.
Karadağ AS, Parish LC
Clin Dermatol 2019 May-Jun;37(3):240-254. Epub 2019 Jan 15 doi: 10.1016/j.clindermatol.2019.01.005. PMID: 31178106
Etiology, diagnosis, and therapeutic management of granuloma annulare: an update.
Thornsberry LA, English JC 3rd
Am J Clin Dermatol 2013 Aug;14(4):279-90. doi: 10.1007/s40257-013-0029-5. PMID: 23696233
Syphilis: uncommon presentations in adults.
Dourmishev LA, Dourmishev AL
Clin Dermatol 2005 Nov-Dec;23(6):555-64. doi: 10.1016/j.clindermatol.2005.01.015. PMID: 16325063
Pimecrolimus-induced tinea incognito.
Crawford KM, Bostrom P, Russ B, Boyd J
Skinmed 2004 Nov-Dec;3(6):352-3. doi: 10.1111/j.1540-9740.2004.03796.x. PMID: 15538091

Clinical prediction guides

Acute Hemorrhagic Edema of Infancy: A Diagnostic Challenge for the General Pediatrician.
Leung AKC, Leong KF, Lam JM
Curr Pediatr Rev 2020;16(4):285-293. doi: 10.2174/1573396316666200727145039. PMID: 32718294
Bilateral Annular Isolated Choroidal Melanocytosis.
Heinze KD, Demirci H, Elner VM
Ophthalmic Surg Lasers Imaging Retina 2019 Mar 1;50(3):e74-e76. doi: 10.3928/23258160-20190301-15. PMID: 30893460
Noninfectious Penile Lesions.
Teichman JMH, Mannas M, Elston DM
Am Fam Physician 2018 Jan 15;97(2):102-110. PMID: 29365226
Drug-induced lupus erythematosus.
Marzano AV, Tavecchio S, Menicanti C, Crosti C
G Ital Dermatol Venereol 2014 Jun;149(3):301-9. PMID: 24819757
Granuloma annulare.
Goucha S, Khaled A, Kharfi M, Fazaa B, Zermani R, Ben Jilani S, Kamoun MR
G Ital Dermatol Venereol 2008 Dec;143(6):359-63. PMID: 19169208

Recent systematic reviews

Atypical presentations of cutaneous leishmaniasis: A systematic review.
Meireles CB, Maia LC, Soares GC, Teodoro IPP, Gadelha MDSV, da Silva CGL, de Lima MAP
Acta Trop 2017 Aug;172:240-254. Epub 2017 May 17 doi: 10.1016/j.actatropica.2017.05.022. PMID: 28526427

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