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Anomalous origin of the circumflex artery from the right sinus of Valsalva

MedGen UID:: 1393333
•Concept ID:: C4476815
•: Anatomical Abnormality

HPO:	HP:0025505

Definition

The circumflex coronary artery originates from the right aortic sinus of Valsalva. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAnomalous origin of the circumflex artery from the right sinus of Valsalva

Abnormal cardiovascular system morphology
- Abnormal vascular morphology
  - Abnormal blood vessel morphology
    - Abnormal systemic arterial morphology
      - Abnormal coronary artery morphology
        Abnormal coronary artery origin
        Anomalous origin of the circumflex artery from the right sinus of Valsalva
        Anomalous origin of the left circumflex artery from the right coronary artery

Recent clinical studies

Etiology

Clinical Outcomes in Adult Patients With an Anomalous Right Coronary Artery from the Left Sinus of Valsalva.

Warner ED, Gulati A, Halpern E, Fischman DL, Ruggiero NJ, Keith SW, Layser RB, McCarey M, Savage MP
Am J Cardiol 2023 Oct 1;204:122-129. Epub 2023 Aug 2 doi: 10.1016/j.amjcard.2023.07.066. PMID: 37541148

Anomalous origin of culprit coronary arteries in acute coronary syndromes.

Tyczyński P, Kukuła K, Pietrasik A, Bochenek T, Dębski A, Oleksiak A, Marona M, Lelek M, Stępińska J, Witkowski A
Cardiol J 2018;25(6):683-690. Epub 2017 Dec 14 doi: 10.5603/CJ.a2017.0142. PMID: 29240961

Anomalous origin of the coronary arteries in children: diagnostic role of three-dimensional coronary MR angiography.

Clemente A, Del Borrello M, Greco P, Mannella P, Di Gregorio F, Romano S, Morra A
Clin Imaging 2010 Sep-Oct;34(5):337-43. doi: 10.1016/j.clinimag.2009.08.030. PMID: 20813295

Anatomic variations and anomalies of the coronary arteries: 64-slice CT angiographic appearance.

Koşar P, Ergun E, Oztürk C, Koşar U
Diagn Interv Radiol 2009 Dec;15(4):275-83. Epub 2009 Dec 2 doi: 10.4261/1305-3825.DIR.2550-09.1. PMID: 19957241

Anomalous circumflex coronary artery: benign or predisposed to selective atherosclerosis.

Samarendra P, Kumari S, Hafeez M, Vasavada BC, Sacchi TJ
Angiology 2001 Aug;52(8):521-6. doi: 10.1177/000331970105200803. PMID: 11512690

See all (31)

Diagnosis

Clinical Outcomes in Adult Patients With an Anomalous Right Coronary Artery from the Left Sinus of Valsalva.

Anomalous origin of coronary artery from the opposite aortic sinus of Valsalva-a single center experience with a therapeutic conundrum.

Lanjewar CP, Kumar D, Sabnis GR, Jare M, Phutane M, Shah HC, Reddy S, Borgaonkar D, Thummar A, Kerkar PG
Indian Heart J 2021 May-Jun;73(3):289-294. Epub 2021 Apr 3 doi: 10.1016/j.ihj.2021.03.012. PMID: 34154744 Free PMC Article

Anomalous Origin of All Coronary Arteries from Right Sinus of Valsalva.

Bollempalli H, Divakaran VG, Kontak AC, Lee PC
Tex Heart Inst J 2020 Apr 1;47(2):170-172. doi: 10.14503/THIJ-18-6830. PMID: 32603455 Free PMC Article

Anomalous origin of culprit coronary arteries in acute coronary syndromes.

Anomalous origin of the left circumflex artery from the right sinus of valsalva: non-ST-segment elevation myocardial infarction.

Lee OH, Yoon GS, Choi SH, Shim HI, Baek YS, Shin SH, Kim DH, Woo SI, Park SD
Intern Med 2015;54(9):1053-6. Epub 2015 May 1 doi: 10.2169/internalmedicine.54.2956. PMID: 25948346

See all (54)

Therapy

Assessing the risk of an anomalous circumflex artery using balloon aortic valvuloplasty prior to transcatheter aortic valve replacement.

Tabachnick D, Obokhae B, Harrington K, Brown DL
Catheter Cardiovasc Interv 2020 Aug;96(2):497-499. Epub 2020 Jan 20 doi: 10.1002/ccd.28695. PMID: 31957913

Congenital anomalous aortic origins of the coronary arteries in adults: a Tunisian coronary arteriography study.

Ouali S, Neffeti E, Sendid K, Elghoul K, Remedi F, Boughzela E
Arch Cardiovasc Dis 2009 Mar;102(3):201-8. Epub 2009 Mar 17 doi: 10.1016/j.acvd.2009.01.001. PMID: 19375674

Imaging of congenital coronary anomalies with multislice computed tomography.

Deibler AR, Kuzo RS, Vöhringer M, Page EE, Safford RE, Patron JN, Lane GE, Morin RL, Gerber TC
Mayo Clin Proc 2004 Aug;79(8):1017-23. doi: 10.4065/79.8.1017. PMID: 15301329

Coronary artery anomalies: assessment with free-breathing three-dimensional coronary MR angiography.

Bunce NH, Lorenz CH, Keegan J, Lesser J, Reyes EM, Firmin DN, Pennell DJ
Radiology 2003 Apr;227(1):201-8. Epub 2003 Feb 11 doi: 10.1148/radiol.2271020316. PMID: 12601193

Percutaneous transluminal coronary angioplasty of anomalous left circumflex coronary artery.

Kimbiris D, Lo E, Iskandrian A
Cathet Cardiovasc Diagn 1987 Nov-Dec;13(6):407-10. doi: 10.1002/ccd.1810130610. PMID: 2961455

See all (5)

Prognosis

Clinical Outcomes in Adult Patients With an Anomalous Right Coronary Artery from the Left Sinus of Valsalva.

Anomalous origin of coronary artery from the opposite aortic sinus of Valsalva-a single center experience with a therapeutic conundrum.

Anomalous origin of culprit coronary arteries in acute coronary syndromes.

Anomalous origin of the left circumflex artery from the right sinus of valsalva: non-ST-segment elevation myocardial infarction.

Lee OH, Yoon GS, Choi SH, Shim HI, Baek YS, Shin SH, Kim DH, Woo SI, Park SD
Intern Med 2015;54(9):1053-6. Epub 2015 May 1 doi: 10.2169/internalmedicine.54.2956. PMID: 25948346

Identification, imaging, functional assessment and management of congenital coronary arterial abnormalities in children.

Friedman AH, Fogel MA, Stephens P Jr, Hellinger JC, Nykanen DG, Tweddell J, Feltes TF, Rome JJ
Cardiol Young 2007 Sep;17 Suppl 2:56-67. doi: 10.1017/S1047951107001163. PMID: 18039399

See all (60)

Clinical prediction guides

Variant origin of three main coronary ostia from the right sinus of Valsalva: report of a rare case.

Dimitrova IN, Gaydarski L, Landzhov B, Olewnik Ł, Zielinska N, Tubbs RS, Georgiev GP
Folia Morphol (Warsz) 2023;82(4):932-935. Epub 2022 Nov 17 doi: 10.5603/FM.a2022.0092. PMID: 36385427

Anomalous origin of coronary artery from the opposite aortic sinus of Valsalva-a single center experience with a therapeutic conundrum.

Anomalous origin of the coronary arteries in children: diagnostic role of three-dimensional coronary MR angiography.

Clemente A, Del Borrello M, Greco P, Mannella P, Di Gregorio F, Romano S, Morra A
Clin Imaging 2010 Sep-Oct;34(5):337-43. doi: 10.1016/j.clinimag.2009.08.030. PMID: 20813295

Visualization of anomalous origin and course of coronary arteries in 748 consecutive symptomatic patients by 64-slice computed tomography angiography.

von Ziegler F, Pilla M, McMullan L, Panse P, Leber AW, Wilke N, Becker A
BMC Cardiovasc Disord 2009 Dec 11;9:54. doi: 10.1186/1471-2261-9-54. PMID: 20003347 Free PMC Article

Anatomic variations and anomalies of the coronary arteries: 64-slice CT angiographic appearance.

Koşar P, Ergun E, Oztürk C, Koşar U
Diagn Interv Radiol 2009 Dec;15(4):275-83. Epub 2009 Dec 2 doi: 10.4261/1305-3825.DIR.2550-09.1. PMID: 19957241

See all (15)

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Anomalous origin of the circumflex artery from the right sinus of Valsalva

Definition

Term Hierarchy

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Supplemental Content

Table of contents

Clinical resources

Consumer resources

Reviews

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