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Avascular necrosis of the head of femur(ANFH)

MedGen UID:
140823
Concept ID:
C0410480
Pathologic Function
Synonyms: FEMORAL HEAD, ASEPTIC NECROSIS OF; FEMORAL HEAD, AVASCULAR NECROSIS OF; ISCHEMIC NECROSIS OF FEMORAL HEAD; OSTEONECROSIS OF FEMORAL HEAD
SNOMED CT: Avascular necrosis of head of femur (203476003); Aseptic necrosis of head of femur (203476003); Osteonecrosis of head of femur (203476003)
 
Related genes: TRPV4, COL2A1
 
OMIM®: 608805

Definition

Necrotic changes in the bone tissue of the femoral head due to interruption of blood supply. [from NCI]

Professional guidelines

PubMed

Shrivastava SK, Kailash
J Biosci 2005 Mar;30(2):269-75. doi: 10.1007/BF02703708. PMID: 15933416

Recent clinical studies

Etiology

Oni OO, Odeyemi AO, Olasinde YT, Odeyemi AO, Olufemi-Aworinde KJ, Abolarin AT, Ala OA
Am J Cardiol 2023 Sep 15;203:175-183. Epub 2023 Jul 25 doi: 10.1016/j.amjcard.2023.06.100. PMID: 37499597
Katchy AU, Anyaehie UE, Nwadinigwe CU, Eyichukwu GO
Niger J Clin Pract 2018 Apr;21(4):492-495. doi: 10.4103/njcp.njcp_182_17. PMID: 29607863
Weissinger M, Grübl A, Pöll G
Acta Chir Orthop Traumatol Cech 2011;78(5):410-5. PMID: 22094154

Diagnosis

Drummond K, Holmes NE
BMJ Case Rep 2024 Jan 16;17(1) doi: 10.1136/bcr-2023-257318. PMID: 38233006Free PMC Article
Downes A, Stanley C, Donnelly R, Murphy T
Surgeon 2023 Dec;21(6):e323-e327. Epub 2023 May 26 doi: 10.1016/j.surge.2023.05.002. PMID: 37244775
Iqbal B, Currie G
Radiography (Lond) 2022 May;28(2):560-564. Epub 2021 Dec 16 doi: 10.1016/j.radi.2021.11.012. PMID: 34922825

Therapy

AlOmran AS
Arch Orthop Trauma Surg 2023 Dec;143(12):7213-7218. Epub 2023 Jul 19 doi: 10.1007/s00402-023-04986-9. PMID: 37466724
Quaranta M, Miranda L, Oliva F, Aletto C, Maffulli N
Br Med Bull 2021 Mar 25;137(1):98-111. doi: 10.1093/bmb/ldaa044. PMID: 33454780
Katchy AU, Anyaehie UE, Nwadinigwe CU, Eyichukwu GO
Niger J Clin Pract 2018 Apr;21(4):492-495. doi: 10.4103/njcp.njcp_182_17. PMID: 29607863
Shrivastava SK, Kailash
J Biosci 2005 Mar;30(2):269-75. doi: 10.1007/BF02703708. PMID: 15933416
Shahane SA, Farhan MJ
Injury 1996 Nov;27(9):663-5. doi: 10.1016/s0020-1383(96)00109-x. PMID: 9039366

Prognosis

Oni OO, Odeyemi AO, Olasinde YT, Odeyemi AO, Olufemi-Aworinde KJ, Abolarin AT, Ala OA
Am J Cardiol 2023 Sep 15;203:175-183. Epub 2023 Jul 25 doi: 10.1016/j.amjcard.2023.06.100. PMID: 37499597
Katchy AU, Anyaehie UE, Nwadinigwe CU, Eyichukwu GO
Niger J Clin Pract 2018 Apr;21(4):492-495. doi: 10.4103/njcp.njcp_182_17. PMID: 29607863
Gupta V, Kaur M, Kundu ZS, Kaplia A, Singh D
Chin J Traumatol 2013;16(2):122-5. PMID: 23540904
Reigstad A
J Trauma 1980 Jul;20(7):603-6. doi: 10.1097/00005373-198007000-00010. PMID: 7392111
Rea E
Med J Zambia 1980 Aug-Sep;14(5):89-90. PMID: 7053010

Clinical prediction guides

AlOmran AS
Arch Orthop Trauma Surg 2023 Dec;143(12):7213-7218. Epub 2023 Jul 19 doi: 10.1007/s00402-023-04986-9. PMID: 37466724
Downes A, Stanley C, Donnelly R, Murphy T
Surgeon 2023 Dec;21(6):e323-e327. Epub 2023 May 26 doi: 10.1016/j.surge.2023.05.002. PMID: 37244775
Quaranta M, Miranda L, Oliva F, Aletto C, Maffulli N
Br Med Bull 2021 Mar 25;137(1):98-111. doi: 10.1093/bmb/ldaa044. PMID: 33454780
Katchy AU, Anyaehie UE, Nwadinigwe CU, Eyichukwu GO
Niger J Clin Pract 2018 Apr;21(4):492-495. doi: 10.4103/njcp.njcp_182_17. PMID: 29607863
Rea E
Med J Zambia 1980 Aug-Sep;14(5):89-90. PMID: 7053010

Recent systematic reviews

Quaranta M, Miranda L, Oliva F, Aletto C, Maffulli N
Br Med Bull 2021 Mar 25;137(1):98-111. doi: 10.1093/bmb/ldaa044. PMID: 33454780

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